Pharmacy Compounding 3

Question 1

Which USP chapter governs sterile compounding in pharmacies?

Accepted Answer

USP <797>

Answer

USP <795>

Answer

USP <800>

Answer

USP <1151>

Question 2

An ISO 5 environment is required for which step during sterile compounding?

Accepted Answer

Critical site manipulation during compounding

Answer

Labeling the final product

Answer

Cleaning the anteroom

Answer

Donning PPE in the buffer room

Question 3

Which type of ointment base is most appropriate when the goal is to maximize drug penetration through the skin?

Accepted Answer

Hydrocarbon (oleaginous) base

Answer

Absorption base

Answer

Water-removable (o/w emulsion) base

Answer

Water-soluble base

Question 4

A prescription requires compounding a suppository. Which base melts at body temperature and is most commonly used for rectal suppositories?

Accepted Answer

Cocoa butter (theobroma oil)

Answer

Polyethylene glycol (PEG)

Answer

Glycerin-gelatin base

Answer

Hydroxypropyl methylcellulose

Question 5

When compounding a solution, which factor most directly affects the rate of dissolution of a solid drug?

Accepted Answer

Particle size of the drug

Answer

Color of the container

Answer

Humidity of the compounding area

Answer

Atmospheric pressure

Question 6

Section 503A of the FDCA exempts compounding pharmacies from FDA approval requirements provided they compound:

Accepted Answer

Based on valid prescriptions for individual identified patients

Answer

In large batches for office use only

Answer

Only OTC drug ingredients

Answer

Only veterinary preparations

Question 7

Which physicochemical property determines whether a drug can be incorporated into a water-soluble suppository base like PEG?

Accepted Answer

Drug solubility in the base

Answer

Molecular weight only

Answer

Melting point of the drug

Answer

Color and taste of the drug