Pharmacy Drug Interactions 2

Question 1

A patient on warfarin starts taking aspirin. What is the primary concern?

Accepted Answer

Increased risk of bleeding

Answer

Decreased anticoagulation effect

Answer

Reduced pain relief

Answer

Elevated blood pressure

Question 2

Which drug, when combined with an SSRI, can cause serotonin syndrome?

Accepted Answer

Tramadol

Answer

Metformin

Answer

Lisinopril

Answer

Metoprolol

Question 3

Grapefruit juice is known to inhibit which enzyme, causing elevated plasma levels of many drugs?

Accepted Answer

CYP3A4

Answer

CYP1A2

Answer

CYP2D6

Answer

CYP2C9

Question 4

Concurrent use of an ACE inhibitor and a potassium-sparing diuretic increases the risk of:

Accepted Answer

Hyperkalemia

Answer

Hypokalemia

Answer

Hyponatremia

Answer

Hypernatremia

Question 5

Ciprofloxacin should not be taken within 2 hours of antacids containing aluminum or magnesium because:

Accepted Answer

Cations chelate ciprofloxacin, reducing absorption

Answer

The combination causes severe GI bleeding

Answer

Ciprofloxacin becomes toxic in alkaline pH

Answer

The interaction causes QT prolongation

Question 6

What type of drug interaction occurs when two drugs with similar CNS depressant effects are combined?

Accepted Answer

Additive/synergistic effect

Answer

Antagonism

Answer

Induction

Answer

Chelation