A neonate with suspected sepsis has cultures drawn and empiric antibiotics are started. Blood culture results at 48 hours show no growth. The neonate has been clinically improving. The BEST course of action is:
-
A
Continue antibiotics for the full 14-day course regardless
-
B
Discontinue antibiotics if clinical status is good and CRP trending down
-
C
Switch to oral antibiotics and discharge home
-
D
Repeat blood cultures daily until negative x3