Pediatric CCRN Exam — Questions and Answers
Question 1: A nurse is titrating norepinephrine for a child in septic shock. Which clinical endpoint best indicates adequate perfusion has been restored?
- Age-appropriate MAP, capillary refill < 2 seconds, and normal urine output (1 mL/kg/hr) (Correct answer)
- Lactate clearance ≥ 10% over 6 hours only
- MAP ≥ 65 mmHg in all age groups
- SpO2 > 95% and heart rate normalization alone
Correct answer: Age-appropriate MAP, capillary refill < 2 seconds, and normal urine output (1 mL/kg/hr)
Perfusion adequacy in pediatric septic shock is assessed with age-appropriate MAP targets, capillary refill time, and urine output, not a single adult threshold.
Question 2: Which finding on a neonatal cardiac assessment most strongly suggests a ductal-dependent congenital heart lesion?
- Cyanosis that worsens with crying
- Loud systolic murmur at the left sternal border
- Differential oxygen saturation (preductal > postductal) (Correct answer)
- Bounding peripheral pulses with wide pulse pressure
Correct answer: Differential oxygen saturation (preductal > postductal)
Preductal SpO2 higher than postductal SpO2 indicates right-to-left shunting through the ductus arteriosus, characteristic of ductal-dependent lesions like coarctation.
Question 3: After suffering from burns that resulted in the epidermis and dermis completely sloughing off, a 16-year-old male patient was taken to the emergency room. What type of burn is that?
- Fourth-degree burn
- Third-degree burn (Correct answer)
- First-degree burn
- Second-degree burn
Correct answer: Third-degree burn
A third-degree burn, also known as a full-thickness burn, involves the complete destruction of both the epidermis and the dermis. This type of burn damages nerve endings, sweat glands, and hair follicles, resulting in a wound that often appears leathery, waxy, or charred and is typically insensate (painless) in the center. The description of the epidermis and dermis completely sloughing off directly corresponds to the definition of a third-degree burn.
Question 4: A school-aged autistic child who has a fractured femur and a suspected brain injury is admitted. Which of the following factors is crucial to encouraging hospital setting adjustment?
- Encourage lots of visitors
- Assign a child life therapist per shift
- Initiate new activities to keep the patient occupied
- Adhere to a home schedule (Correct answer)
Correct answer: Adhere to a home schedule
Children with autism spectrum disorder thrive on routine and predictability, and deviations can cause significant anxiety and distress. Adhering to a home schedule as much as possible provides a sense of familiarity and control in the unfamiliar hospital environment. This consistency helps reduce agitation and promotes better adjustment and cooperation with care.
Question 5: The nurse's initial step in treating a patient who has hypovolemic shock as a result of persistent vomiting should be to:
- Prepare the patient for central venous line placement
- Prepare equipment for intubation
- Administer oxygen (Correct answer)
- Increase intravenous fluid rate
Correct answer: Administer oxygen
In any shock state, including hypovolemic shock, the initial priority is to ensure adequate oxygenation and ventilation, following the ABCs (Airway, Breathing, Circulation). Administering oxygen helps improve tissue oxygen delivery, which is compromised due to reduced blood volume and perfusion. While fluid resuscitation is critical, ensuring oxygen supply to vital organs is the very first step to mitigate cellular damage.
Question 6: Which medication used for sedation in the PICU is associated with propofol infusion syndrome (PRIS) and is generally AVOIDED in children for long-term sedation?
- Ketamine
- Midazolam
- Dexmedetomidine
- Propofol (Correct answer)
Correct answer: Propofol
Propofol infusion syndrome — characterized by metabolic acidosis, rhabdomyolysis, cardiac failure, and death — is a rare but fatal complication, and propofol is generally avoided for prolonged pediatric sedation.
Question 7: The parents of a 3-year-old hospitalized with hemophilia receive advice from the nurse on caring for their kid at home. Which of the following parent-made statements suggests the need for more instructions?
- “We will avoid having the child receive immunizations and cancel the scheduled dental appointments.” (Correct answer)
- “We will remove household items that can easily fall over.”
- “We will pad corners of the furniture.”
- “We will supervise the child closely.”
Correct answer: “We will avoid having the child receive immunizations and cancel the scheduled dental appointments.”
Avoiding immunizations and canceling dental appointments for a child with hemophilia is incorrect and indicates a need for further instruction. Children with hemophilia still require immunizations, which should be administered subcutaneously with a small-gauge needle and pressure applied to minimize bleeding risk. Regular dental care is crucial to prevent gum disease and tooth decay, which could lead to more invasive procedures and potential bleeding complications.
Question 8: When patient attributes and nursing competencies are aligned, optimal outcomes in terms of the AACN Synergy Model for Patient Care occur. From the standpoint of the patient and family, outcomes should contain everything listed below, EXCEPT:
- Functional changes
- Quality of life
- Physiologic changes (Correct answer)
- Behavioral changes
Correct answer: Physiologic changes
The AACN Synergy Model for Patient Care emphasizes that optimal outcomes occur when patient needs align with nursing competencies. From the perspective of the patient and family, outcomes are typically described in terms of their lived experience, such as improvements in functional abilities, quality of life, and behavioral adaptations. While nurses certainly influence physiological changes, these are often considered more objective, medical-centric measures rather than the subjective, holistic outcomes prioritized by the patient and family within this model.
Question 9: A little child with colitis is admitted. The patient experiences respiratory discomfort, abdominal distention, and capillary refill times longer than four seconds eight hours after being admitted. The nurse should have what following suspicions?
- Malrotation with Volvulus
- Bowel Perforation (Correct answer)
- Intussusception
- Splenic Rupture
Correct answer: Bowel Perforation
A child with colitis experiencing respiratory discomfort, abdominal distention, and prolonged capillary refill times (indicating poor perfusion and potential shock) suggests a severe, acute abdominal complication. Bowel perforation is a life-threatening emergency where a hole in the intestinal wall leads to the leakage of contents into the abdominal cavity, causing peritonitis, sepsis, and potentially septic shock. These signs are highly indicative of such a critical event.
Question 10: A 10 kg child requires an epinephrine infusion at 0.1 mcg/kg/min. Using the rule of 6, how many mg of epinephrine should be added to 100 mL of D5W to run at 1 mL/hr?
- 60 mg
- 6 mg
- 0.06 mg
- 0.6 mg (Correct answer)
Correct answer: 0.6 mg
Rule of 6: weight (kg) × 0.6 = mg to add to 100 mL; for 10 kg: 10 × 0.06 = 0.6 mg, resulting in a concentration where 1 mL/hr delivers 0.1 mcg/kg/min.
Question 11: The ICU is caring for a patient with an end-stage pituitary adenoma who also has diabetes insipidus and aspiration pneumonia. The mother is giving the patient water and soft beverages despite being aware that there is a plan for transpyloric tube feedings and nothing by mouth. What action should the nurse take in this circumstance?
- Request a modification to the diet plan so that oral fluids are included.
- Request that the mother's access to the ICU be limited by security
- Ask the mother to explain why she is giving fluids to her son (Correct answer)
- Report the mother's interference with the treatment plan to the social worker.
Correct answer: Ask the mother to explain why she is giving fluids to her son
The nurse's initial action should always be to engage in therapeutic communication to understand the parent's perspective and reasoning. Asking the mother why she is giving fluids allows the nurse to assess her understanding of the NPO status and the child's condition, identify any cultural beliefs, or address potential misinformation. This approach fosters trust and provides an opportunity for education before escalating the situation.
Question 12: Which ventilator mode delivers a guaranteed tidal volume while limiting peak inspiratory pressure in pediatric patients?
- Synchronized intermittent mandatory ventilation (SIMV)
- Volume-guaranteed (VG) mode (Correct answer)
- Airway pressure release ventilation (APRV)
- Pressure-controlled ventilation (PCV)
Correct answer: Volume-guaranteed (VG) mode
Volume-guaranteed mode delivers a set tidal volume while automatically adjusting pressure to the minimum required, protecting against volutrauma and pressure injury.
Question 13: A child with AKI has a serum sodium of 122 mEq/L and is actively seizing. What is the most appropriate immediate intervention?
- Free water restriction only
- Furosemide with normal saline
- 3% hypertonic saline bolus (Correct answer)
- Normal saline at maintenance rate
Correct answer: 3% hypertonic saline bolus
Symptomatic severe hyponatremia with seizures requires urgent correction using 3% hypertonic saline to raise serum sodium by 1–2 mEq/L/hr until symptoms resolve.
Question 14: What is the TARGET cerebral perfusion pressure (CPP) range recommended for a 6-year-old with severe TBI?
- 30–40 mmHg
- 70–80 mmHg
- 50–60 mmHg (Correct answer)
- 40–50 mmHg
Correct answer: 50–60 mmHg
Pediatric TBI guidelines recommend maintaining CPP between 40–65 mmHg (age-dependent), with 50–60 mmHg generally appropriate for school-age children to ensure adequate brain perfusion.
Question 15: A child in the PICU has an intracranial pressure (ICP) of 28 mmHg and a mean arterial pressure (MAP) of 70 mmHg. What is the cerebral perfusion pressure (CPP)?
- 42 mmHg (Correct answer)
- 28 mmHg
- 70 mmHg
- 98 mmHg
Correct answer: 42 mmHg
CPP = MAP − ICP = 70 − 28 = 42 mmHg; adequate pediatric CPP should be maintained above 40–50 mmHg.
Question 16: A new diagnosis of hypertrophic cardiomyopathy has been made in an adolescent who experienced cardiac arrest. The parents worry about what to do if their son passes out once more. The best response from the nurse would be:
- "I will have your son's cardiologist speak with you."
- "Would teaching you CPR help ease your anxieties?" (Correct answer)
- "Do you know how to access the EMS system?"
- "Now that your son has been diagnosed and treated, you need not worry."
Correct answer: "Would teaching you CPR help ease your anxieties?"
The parents' anxiety stems from the fear of their son passing out again and not knowing how to respond. Teaching them CPR directly addresses this fear by empowering them with a life-saving skill. This provides a sense of control and preparedness for potential emergencies, which is vital for coping with a child's serious cardiac condition.
Question 17: Which opioid is CONTRAINDICATED in a child with renal failure requiring pain management in the PICU?
- Fentanyl
- Hydromorphone
- Meperidine (Correct answer)
- Morphine
Correct answer: Meperidine
Meperidine's active metabolite normeperidine accumulates in renal failure, causing CNS excitation, tremors, and seizures, making it contraindicated in patients with impaired renal function.
Question 18: Which daily routine should be included in the bundle to lower the frequency of central line-associated bloodstream infections?
- Replacement of the catheter
- Replacement of the infusion tubing
- Review of antibiotics
- Review of catheter necessity (Correct answer)
Correct answer: Review of catheter necessity
A crucial component of central line-associated bloodstream infection (CLABSI) prevention bundles is the daily review of catheter necessity. By regularly assessing if the central line is still essential for patient care, unnecessary catheters can be removed promptly. Removing catheters as soon as they are no longer needed significantly reduces the duration of exposure and the overall risk of infection.
Question 19: A 4-year-old presents with bloody diarrhea, thrombocytopenia, microangiopathic hemolytic anemia, and acute kidney injury. What is the most likely diagnosis?
- Henoch-Schönlein purpura
- Hemolytic uremic syndrome (Correct answer)
- Acute glomerulonephritis
- Nephrotic syndrome
Correct answer: Hemolytic uremic syndrome
The classic triad of microangiopathic hemolytic anemia, thrombocytopenia, and AKI following bloody diarrhea is the hallmark presentation of hemolytic uremic syndrome (HUS).
Question 20: To get a cardiac biopsy, a pediatric patient is getting ready for a cardiac catheterization. Which allergies need to be examined for before performing this procedure on the patient?
- Iodine or shellfish (Correct answer)
- Opioid pain medications
- Penicillin
- Antiarrhythmic medications
Correct answer: Iodine or shellfish
Cardiac catheterization procedures typically involve the use of iodinated contrast dye to visualize the heart chambers and blood vessels. Therefore, it is crucial to assess for allergies to iodine or shellfish, as these indicate a potential hypersensitivity reaction to the contrast agent. An allergic reaction to the contrast dye can range from mild to severe, including anaphylaxis, making pre-procedure screening essential for patient safety.
Question 21: A 3-year-old has an intracranial pressure (ICP) of 28 mmHg with a mean arterial pressure of 65 mmHg. What is the calculated cerebral perfusion pressure (CPP)?
- 65 mmHg
- 93 mmHg
- 28 mmHg
- 37 mmHg (Correct answer)
Correct answer: 37 mmHg
CPP = MAP − ICP = 65 − 28 = 37 mmHg, which is critically low and indicates inadequate cerebral perfusion requiring urgent intervention.
Question 22: Which disease is frequently linked to pulmonary hypertension (PH) in most pediatric patients?
- Asthma
- Thoracic trauma
- Congenital heart disease (CHD) (Correct answer)
- Bronchopulmonary dysplasia (BPD)
Correct answer: Congenital heart disease (CHD)
Congenital heart disease (CHD) is frequently linked to pulmonary hypertension (PH) in pediatric patients, especially those with left-to-right shunts like VSDs or PDAs. The increased blood flow and pressure to the pulmonary arteries over time cause structural changes and remodeling of the pulmonary vasculature. This leads to elevated pulmonary vascular resistance and the development of pulmonary hypertension.
Question 23: Which EEG pattern in a critically ill child indicates the HIGHEST risk for poor neurological outcome?
- Low-amplitude theta activity
- Burst suppression pattern (Correct answer)
- Generalized slowing
- Sleep spindles present
Correct answer: Burst suppression pattern
Burst suppression on EEG — periods of near-electrical silence alternating with bursts of activity — indicates severe diffuse cortical dysfunction and is associated with poor neurological prognosis.
Question 24: A child with Guillain-Barré syndrome has a forced vital capacity (FVC) of 18 mL/kg. Based on the '20-30-40 rule,' what intervention is indicated?
- Encourage deep breathing exercises only
- Initiate BiPAP immediately
- Administer IVIG and observe
- Elective intubation for airway protection (Correct answer)
Correct answer: Elective intubation for airway protection
The 20-30-40 rule states that FVC <20 mL/kg, maximum inspiratory pressure > −30 cmH2O, or maximum expiratory pressure <40 cmH2O indicates respiratory failure risk requiring elective intubation.
Question 25: During the postictal phase of a tonic-clonic seizure characterized by uncontrollable limb jerking and loss of consciousness, a nurse is providing postictal care for a 7-year-old male patient in the PICU. What results can be anticipated from this phase?
- Crying, "pins-and-needles" sensation, tachycardia
- Drowsiness, headache, nausea (Correct answer)
- Aura, loss of appetite, insomnia
- Immediate return to baseline behavior
Correct answer: Drowsiness, headache, nausea
The postictal phase is the recovery period immediately following a seizure. During this time, the brain is recovering from intense electrical activity, leading to common symptoms such as drowsiness, confusion, and fatigue. Patients may also experience headaches, muscle soreness, and sometimes nausea or vomiting as their body recovers from the physiological stress of the seizure.
Question 26: What is breathing difficulty?
- The abnormalities of breathing heavily
- None of the above
- An act that prevents needed gas exchange (Correct answer)
- The difficulty in breathing
Correct answer: An act that prevents needed gas exchange
Breathing difficulty, or dyspnea, is the subjective sensation of uncomfortable or labored breathing. Physiologically, it often arises when the body's demand for gas exchange—taking in sufficient oxygen and expelling carbon dioxide—is not adequately met. This can be caused by various underlying conditions that impair the efficiency of the respiratory system, thereby preventing needed gas exchange.
Question 27: A 2-year-old who is on a ventilator has spent her entire life in a hospital. The patient will be sent home in a week with a gastrostomy and tracheostomy, according to the doctor. As a way to assess the discharge requirements of the patient, the nurse must arrange for:
- Home nursing care for the first few days following discharge
- A multidisciplinary care conference before discharge
- An outreach educator to determine the learning needs of the family
- A social worker to meet with the family and assess adequacy of the home environment (Correct answer)
Correct answer: A social worker to meet with the family and assess adequacy of the home environment
For a child with complex medical needs like a ventilator, gastrostomy, and tracheostomy, a social worker is essential for assessing the home environment's adequacy. They evaluate the family's resources, support systems, and ability to manage the child's care at home. This assessment ensures a safe and successful transition from hospital to home, addressing practical and psychosocial challenges.
Question 28: A family whose child has cerebral palsy and will be receiving a baclofen (Lioresal) pump to treat spasticity is receiving patient education from the nurse. Which of the following should the nurse emphasize in the conversation?
- Gamma-aminobutyric acid (GABA), a neurotransmitter, is inhibited by the drug.
- Parents can be taught to regulate the dosage based on symptoms.
- Parents must bring the child back to the clinic to have medicine added to the pump. (Correct answer)
- The child will have a normal gait after insertion of the pump.
Correct answer: Parents must bring the child back to the clinic to have medicine added to the pump.
Intrathecal baclofen pumps deliver medication directly into the spinal fluid, requiring specialized knowledge and sterile technique for refills. Parents cannot regulate the dosage or refill the pump themselves due to the complexity and risk of infection or overdose. Therefore, regular clinic visits for pump refills by trained professionals are essential for safe and effective management of spasticity.
Question 29: Which of the subsequent interventions would be most beneficial in helping to manage a child who needs PEEP of 14 cm water?
- Extracorporeal membrane oxygenation (ECMO)
- Placement of a thoracostomy tube
- Placement of a pulmonary artery catheter
- High-frequency oscillatory ventilation (HFOV) (Correct answer)
Correct answer: High-frequency oscillatory ventilation (HFOV)
A PEEP of 14 cm water indicates severe lung disease and significant challenges with oxygenation and ventilation. High-frequency oscillatory ventilation (HFOV) is a specialized mode of mechanical ventilation often used in pediatric patients with severe acute respiratory distress syndrome (ARDS) or other severe lung conditions. HFOV delivers very small tidal volumes at very high frequencies, which can provide better oxygenation and CO2 removal while minimizing lung injury, especially when conventional ventilation with high PEEP is insufficient or causing barotrauma.
Question 30: When calculating maintenance IV fluids using the Holliday-Segar method for a 25 kg child, how many mL/hour should be administered?
- 100 mL/hr
- 85 mL/hr
- 75 mL/hr
- 65 mL/hr (Correct answer)
Correct answer: 65 mL/hr
Holliday-Segar: 100 mL/kg for first 10 kg (1000) + 50 mL/kg for next 10 kg (500) + 20 mL/kg for remaining 5 kg (100) = 1600 mL/day ÷ 24 = ~65 mL/hr.
Question 31: Which of the following graft types is frequently derived from cadaver skin and is frequently utilized in the treatment of pediatric burn wounds?
- Heterograft
- Allograft (Correct answer)
- Autograft
- Xenograft
Correct answer: Allograft
An allograft, also known as a homograft, is a tissue graft taken from a donor of the same species but a different genetic makeup. In pediatric burn care, cadaver skin is frequently used as an allograft. These grafts serve as temporary biological dressings to cover extensive burn wounds, providing a protective barrier against infection and fluid loss while promoting healing until the patient's own skin (autograft) can be harvested.
Question 32: Which parameter is MOST important to monitor in a child receiving IV amiodarone for arrhythmia control?
- Platelet count
- Serum potassium only
- Liver function, thyroid function, and pulmonary function (Correct answer)
- Serum creatinine
Correct answer: Liver function, thyroid function, and pulmonary function
Amiodarone has multi-organ toxicities including hepatotoxicity, thyroid dysfunction (hypo or hyperthyroidism), and pulmonary toxicity, requiring regular monitoring of liver, thyroid, and pulmonary function.
Question 33: The amount of hemolyzed blood samples that have been recorded by the lab, from the perspective of a nurse it is overwhelming. The nurse's best course of action would be to:
- Create a poster and post-test demonstrating the proper method of drawing blood samples
- Track the number of blood samples drawn, by what method and the number reported as hemolyzed (Correct answer)
- Request a staff meeting to discuss the problem and ask for feedback
- Develop an educational in-service on the proper blood-sampling technique for the staff
Correct answer: Track the number of blood samples drawn, by what method and the number reported as hemolyzed
The first step in addressing a quality improvement issue, such as a high rate of hemolyzed blood samples, is to gather objective data. Tracking specific details like the method of blood draw (e.g., venipuncture vs. IV line) and the number of hemolyzed samples helps identify patterns, potential root causes, and areas for targeted intervention. This data-driven approach is essential for effective problem-solving.
Question 34: What is the MOST common trigger for status asthmaticus requiring PICU admission in children?
- Exercise-induced bronchospasm
- Viral upper respiratory infection (Correct answer)
- Cold air inhalation
- Allergen exposure
Correct answer: Viral upper respiratory infection
Viral URIs (most commonly rhinovirus) are the predominant trigger for acute severe asthma exacerbations requiring pediatric intensive care unit admission.
Question 35: A 2-year-old with bronchiolitis on high-flow nasal cannula has worsening work of breathing. What parameter BEST indicates the need to escalate to non-invasive ventilation?
- SpO2 of 93% on 6 L/min flow
- Temperature of 38.5°C
- Respiratory rate of 60 with subcostal retractions and poor feeding (Correct answer)
- Mild expiratory wheeze bilaterally
Correct answer: Respiratory rate of 60 with subcostal retractions and poor feeding
Increasing work of breathing with retractions, tachypnea, and poor feeding despite high-flow oxygen signals impending respiratory failure requiring escalation to CPAP or BiPAP.
Question 36: Which ventilator strategy is recommended for pediatric ARDS to minimize ventilator-induced lung injury?
- Low tidal volumes (4–6 mL/kg) with permissive hypercapnia (Correct answer)
- Volume-assured pressure support without PEEP
- High tidal volumes (12 mL/kg) with low PEEP
- Pressure control with FiO2 1.0 at all times
Correct answer: Low tidal volumes (4–6 mL/kg) with permissive hypercapnia
Lung-protective ventilation using low tidal volumes (4–6 mL/kg IBW) with permissive hypercapnia minimizes volutrauma and barotrauma in pediatric ARDS.
Question 37: A nurse is educating the family of a baby who has congenital heart disease (CHD) and the DiGeorge syndrome. Prior to delivery, the baby's condition was unclear to the family. </br> </br> What types of help and proactive guidance should be presented?
- During resuscitative measures and procedures, limit and/or avoid family presence since the diagnosis was a shock
- Reassure the family that the infant's condition will not interfere with normal growth and development
- Arrange social work, palliative care, and genetics referrals
- Encourage breastfeeding and pumping to maintain supply (Correct answer)
Correct answer: Encourage breastfeeding and pumping to maintain supply
For infants with congenital heart disease (CHD), breastfeeding and breast milk offer numerous benefits, including enhanced immunity, easier digestion, and optimal nutrition, which are crucial for their fragile health. Encouraging breastfeeding or pumping helps maintain the mother's milk supply, providing the best possible nutritional support for the infant's growth and development. This proactive guidance supports the infant's overall well-being and resilience.
Question 38: What does an airway opening (for surgical purposes) entail?
- Airing
- Tracheotomy (Correct answer)
- Airpath
- Masking
Correct answer: Tracheotomy
A tracheotomy is a surgical procedure that involves creating an incision in the neck to make an opening directly into the trachea (windpipe). This opening, known as a tracheostomy, is established to bypass an upper airway obstruction, facilitate breathing, or provide a secure airway for long-term mechanical ventilation. It is a critical intervention for managing severe airway issues.
Question 39: A 6-year-old with bacterial meningitis develops sudden unilateral pupil dilation, bradycardia, and hypertension. The nurse recognizes this as:
- Medication side effect from mannitol
- Cushing's triad indicating herniation (Correct answer)
- SIADH causing cerebral edema correction
- Normal sympathetic response to pain
Correct answer: Cushing's triad indicating herniation
Cushing's triad (bradycardia, hypertension, irregular respirations) with pupil changes indicates brainstem herniation—a neurologic emergency.
Question 40: Which inhaled agent is used as rescue therapy in pediatric acute severe asthma unresponsive to standard bronchodilators?
- Heliox (helium-oxygen mixture) (Correct answer)
- Sodium bicarbonate nebulization
- Nitric oxide
- Isoflurane
Correct answer: Heliox (helium-oxygen mixture)
Heliox reduces gas turbulence in narrowed airways, decreasing work of breathing and improving distal bronchodilator delivery in severe asthma refractory to standard therapy.
Question 41: Which finding on a chest X-ray is CHARACTERISTIC of surfactant deficiency (respiratory distress syndrome) in a premature neonate?
- Hyperinflation with flattened diaphragms
- Cardiomegaly with pulmonary edema
- Unilateral opacification with mediastinal shift
- Diffuse ground-glass opacity with air bronchograms (Correct answer)
Correct answer: Diffuse ground-glass opacity with air bronchograms
RDS produces a diffuse ground-glass or 'white-out' pattern with air bronchograms on CXR due to widespread atelectasis from surfactant deficiency in premature lungs.
Question 42: A PICU nurse is preparing to administer a blood transfusion to a 2-year-old. What is the standard weight-based volume for a packed red blood cell transfusion in pediatrics?
- 20 mL/kg
- 5 mL/kg
- 30 mL/kg
- 10–15 mL/kg (Correct answer)
Correct answer: 10–15 mL/kg
The standard pediatric PRBC transfusion dose is 10–15 mL/kg, infused over 2–4 hours, to raise hemoglobin by approximately 2–3 g/dL.
Question 43: Which of the following describes the fat embolism syndrome (FES)'s most typical showing feature in children?
- Anemia and thrombocytopenia
- Petechial rash
- Neurologic abnormalities
- Pulmonary manifestations (Correct answer)
Correct answer: Pulmonary manifestations
Fat embolism syndrome (FES) typically presents with a classic triad of symptoms: respiratory distress, neurological abnormalities, and a petechial rash. However, pulmonary manifestations, such as dyspnea, tachypnea, hypoxemia, and diffuse infiltrates on chest X-ray, are the most common and often the earliest signs to appear. These occur as fat globules embolize to the pulmonary capillaries, causing inflammation and impaired gas exchange.
Question 44: A 3-year-old presents with inspiratory stridor, a barking cough, and low-grade fever. Which intervention is the priority?
- Start IV antibiotics for suspected epiglottitis
- Perform immediate endotracheal intubation
- Obtain chest X-ray before any treatment
- Administer nebulized racemic epinephrine (Correct answer)
Correct answer: Administer nebulized racemic epinephrine
Nebulized racemic epinephrine rapidly reduces subglottic edema in croup, providing immediate airway relief.
Question 45: A young child may have pinworms because of how he described his initial sensations:
- Loose bowel movement
- Maculopapular rash
- Scaly skin patches
- Anal itching (Correct answer)
Correct answer: Anal itching
Pinworm infections (enterobiasis) are classically characterized by intense anal itching, especially at night. This occurs because the female pinworms migrate from the rectum to the perianal region to lay their eggs, causing significant irritation and pruritus. The itching can be severe enough to disrupt sleep and is the most common symptom described by affected children.
Question 46: Which CSF finding is MOST consistent with bacterial meningitis in a child?
- Xanthochromic CSF, RBC 10,000, WBC 50
- Clear CSF, WBC 300 (lymphocytic), glucose 55, protein 80
- Clear CSF, WBC 10 (lymphocytic), glucose 60, protein 30
- Cloudy CSF, WBC 2,000 (neutrophilic), glucose 25, protein 200 (Correct answer)
Correct answer: Cloudy CSF, WBC 2,000 (neutrophilic), glucose 25, protein 200
Bacterial meningitis produces cloudy CSF with a high neutrophilic pleocytosis, very low glucose (<40 mg/dL or CSF:serum ratio <0.4), and elevated protein due to purulent inflammation.
Question 47: When treating a baby with persistent pulmonary hypertension, the primary objective is to:
- Maintain the pH level at less than 7.40
- Dilate the systemic vascular bed
- Maintain fetal pulmonary circulation
- Dilate the pulmonary vascular bed (Correct answer)
Correct answer: Dilate the pulmonary vascular bed
Persistent pulmonary hypertension of the newborn (PPHN) is characterized by high pulmonary vascular resistance, which prevents adequate blood flow to the lungs for oxygenation. The primary objective of treatment is to dilate the pulmonary vascular bed, thereby reducing pulmonary vascular resistance. This allows more blood to flow through the lungs, improving oxygen uptake and systemic oxygenation.
Question 48: A nurse is interested in integrating other academic fields into the NICU's educational program for developmental care. The best strategy to persuade management that this project is profitable is to:
- Request that the neonatologist present the plan.
- Present a report summarizing research relating developmental care to decrease length of stay. (Correct answer)
- Present case studies demonstrating favorable outcomes for developmental care.
- Invite members of administration to attend the classes.
Correct answer: Present a report summarizing research relating developmental care to decrease length of stay.
To persuade management, it is crucial to demonstrate the tangible benefits of the proposed project, especially in terms of cost-effectiveness and improved outcomes. Presenting research that links developmental care to a decreased length of stay directly shows financial savings and increased efficiency. This evidence-based approach is highly effective in gaining administrative support for new initiatives.
Question 49: Which medication is the drug of choice to close a hemodynamically significant patent ductus arteriosus in a premature neonate?
- Furosemide
- Indomethacin (Correct answer)
- Prostaglandin E1
- Digoxin
Correct answer: Indomethacin
Indomethacin, a prostaglandin synthesis inhibitor (NSAID), promotes ductal closure by reducing prostaglandin E2, which normally keeps the ductus open.
Question 50: Which of the following group of children might have a hypertensive crisis as shown by acidosis, hypothermia, and alveolar hypoxia?
- Those with increases in ventricular afterload.
- Those with sustained increases in afterload
- Those with reactive pulmonary vascular bed (Correct answer)
- Those with systemic vascular disease.
Correct answer: Those with reactive pulmonary vascular bed
A reactive pulmonary vascular bed is prone to vasoconstriction, leading to increased pulmonary vascular resistance and pulmonary hypertension. This can cause a hypertensive crisis in the pulmonary circulation, resulting in poor gas exchange, alveolar hypoxia, and subsequent metabolic acidosis. Hypothermia can also be a consequence of severe physiological stress and poor perfusion in such critical states.
Question 51: An adolescent who has previously been admitted for chronic status asthmaticus is getting ready to go home. Because taking his prescription "makes him feel too different" from his peers, the nurse concludes that the patient has not been taking his drugs as prescribed. The nurse needs to:
- Advise the parents to withhold privileges if the patient remains non-compliant.
- Refer the patient to a support group for adolescents with asthma (Correct answer)
- Provide the patient with articles on the relationship of hospitalization and medication compliance.
- Arrange for the patient's school nurse to monitor compliance
Correct answer: Refer the patient to a support group for adolescents with asthma
Adolescents often struggle with medication adherence due to peer pressure and a desire to fit in. Referring the patient to a support group for adolescents with asthma can provide a safe space to share experiences and coping strategies with peers facing similar challenges. This can help reduce feelings of isolation and improve motivation for medication compliance by normalizing their condition.
Question 52: A 9-year-old with sickle cell disease presents with acute chest syndrome. Which set of interventions is most appropriate?
- Aggressive diuresis and high-dose steroids
- Hydroxyurea loading dose and immediate plasmapheresis
- IV antibiotics alone, withholding fluids to prevent sickling
- Supplemental O2, IV hydration, analgesics, and exchange transfusion if severe (Correct answer)
Correct answer: Supplemental O2, IV hydration, analgesics, and exchange transfusion if severe
Acute chest syndrome is managed with supplemental oxygen, careful hydration, analgesia, antibiotics, and exchange transfusion for severe hypoxemia.
Question 53: According to KDIGO criteria, which urine output threshold defines oliguria and indicates acute kidney injury (AKI) in a pediatric patient?
- < 0.5 mL/kg/hr for 6 hours (Correct answer)
- < 0.3 mL/kg/hr for 6 hours
- < 1 mL/kg/hr for 4 hours
- < 2 mL/kg/hr for 8 hours
Correct answer: < 0.5 mL/kg/hr for 6 hours
KDIGO criteria define oliguria as urine output < 0.5 mL/kg/hr for 6 or more consecutive hours, which is a diagnostic criterion for AKI staging.
Question 54: A neonate at 28 weeks gestation requires surfactant therapy. What is the PRIMARY mechanism by which exogenous surfactant improves oxygenation?
- Stimulates type II pneumocyte maturation
- Reduces pulmonary vascular resistance
- Decreases alveolar surface tension to prevent collapse (Correct answer)
- Increases mucociliary clearance
Correct answer: Decreases alveolar surface tension to prevent collapse
Exogenous surfactant replaces deficient endogenous surfactant, reducing alveolar surface tension and preventing atelectasis to improve ventilation-perfusion matching and oxygenation.
Question 55: Which vasoactive agent is MOST appropriate as first-line therapy for a child in septic shock with poor cardiac contractility?
- Dopamine
- Norepinephrine
- Dobutamine (Correct answer)
- Vasopressin
Correct answer: Dobutamine
Dobutamine is a beta-1 agonist that increases myocardial contractility, making it the preferred agent when septic shock is accompanied by poor cardiac function.
Question 56: While patients are sleeping, a nursing unit must be able to put patients back on ventilator support as directed. The respiratory therapist is only sometimes present on the unit to put patients on the ventilator because of staffing patterns. The nurse should respond in the following ways:
- Wait for the therapist to intervene.
- Place the patient on the ventilator when needed, despite current policy
- Question the current policy that only respiratory therapists can manage the ventilator. (Correct answer)
- Ask the parent to be responsible for this task.
Correct answer: Question the current policy that only respiratory therapists can manage the ventilator.
In a situation where patients need ventilator support but respiratory therapists are not consistently available, the nurse should question the policy restricting ventilator management to only respiratory therapists. This policy creates a safety risk for patients. Advocating for policy changes, such as training nurses for basic ventilator management, ensures timely and safe patient care, aligning with the nurse's role in patient advocacy and quality improvement.
Question 57: A 12-year-old with asthma is on IV magnesium sulfate. Which adverse effect requires IMMEDIATE intervention?
- Mild nausea
- Loss of patellar reflexes (Correct answer)
- Flushing and warmth
- Transient hypotension
Correct answer: Loss of patellar reflexes
Loss of deep tendon reflexes (patellar reflex) is an early sign of magnesium toxicity preceding respiratory depression and cardiac arrest; the infusion must be stopped immediately.
Question 58: A diabetic child who passed out in class is hospitalized. He has tachycardia, short breathing, dilated pupils, and hyperreflexia at admission. The treatment strategy would involve providing:
- Naloxone (Narcan) IV
- 25% Dextrose IV (Correct answer)
- Regular insulin SQ
- Glucagon IM
Correct answer: 25% Dextrose IV
The child's symptoms of passing out, tachycardia, short breathing, dilated pupils, and hyperreflexia are classic signs of severe hypoglycemia (low blood sugar). In an unconscious or severely symptomatic diabetic child, immediate intravenous administration of 25% Dextrose is crucial to rapidly raise blood glucose levels. This provides immediate glucose to the brain and other tissues, reversing the life-threatening effects of hypoglycemia.
Question 59: A 2-year-old ingests an unknown medication and presents with miosis, bradycardia, excessive secretions, and muscle fasciculations. Which antidote is INDICATED?
- Flumazenil
- Digoxin-specific antibody fragments
- Naloxone
- Atropine and pralidoxime (2-PAM) (Correct answer)
Correct answer: Atropine and pralidoxime (2-PAM)
Miosis, bradycardia, secretions, and fasciculations represent cholinergic toxidrome from organophosphate or carbamate poisoning; atropine reverses muscarinic effects while pralidoxime reactivates acetylcholinesterase.
Question 60: Esophageal varices that are bleeding may be treated acutely by?
- Immediate surgical intervention
- Placement of a large NGT to low intermittent suction
- Placement of a central venous line for hyperalimentation (TPN)
- Administration of octreotide (Sandostatin) (Correct answer)
Correct answer: Administration of octreotide (Sandostatin)
Acute bleeding from esophageal varices is a life-threatening emergency. Octreotide (Sandostatin) is a somatostatin analog that causes splanchnic vasoconstriction, which reduces blood flow to the portal system and subsequently lowers pressure within the esophageal varices. This pharmacological action helps to control and stop the acute variceal bleeding, making it a primary intervention in the immediate management of this condition.
Question 61: Due to staffing patterns, the respiratory therapist is not always present on the unit to place patients on the ventilator, so a nursing unit needs to be able to put patients back on ventilator support as directed, when patients are napping. The nurse should respond in the following ways:
- Question the current policy that only respiratory therapists can manage the ventilator. (Correct answer)
- Place the patient on the ventilator when needed, despite current policy
- Ask the parent to be responsible for this task.
- Wait for the therapist to intervene.
Correct answer: Question the current policy that only respiratory therapists can manage the ventilator.
Nurses are patient advocates and should question policies that create barriers to timely and safe patient care. If nurses are competent to place patients on ventilators and delays by respiratory therapists compromise patient safety, questioning the policy is appropriate. This initiates a dialogue to review protocols and potentially expand nursing scope of practice to ensure optimal patient outcomes.
Question 62: A nurse provides medical attention to a little child in the pediatric intensive care unit (PICU) who has had a cardiac catheterization to repair a ventricular septal defect (VSD). What kind of heart arrhythmia is the MOST typical to develop as a side effect of VSD repair?
- Premature ventricular contractions (PVCs)
- Heart Block (Correct answer)
- Atrial fibrillation (A-fib)
- Supraventricular tachycardia (SVT)
Correct answer: Heart Block
Heart block is the most typical heart arrhythmia to develop as a side effect of ventricular septal defect (VSD) repair. The VSD is located in close proximity to the heart's conduction system, particularly the bundle of His. Surgical closure of the defect carries a risk of trauma or damage to these delicate conduction pathways, which can result in varying degrees of heart block.
Question 63: Infants born prematurely face a serious risk of intracranial hemorrhage (ICH), which is divided into four classes. Which grade involves intraventricular blood among the following?
- Grade IV
- Grade I
- Grade III
- Grade II (Correct answer)
Correct answer: Grade II
Intracranial hemorrhage (ICH) in premature infants is graded based on its severity and location. Grade I involves germinal matrix hemorrhage only, without intraventricular extension. Grade II is characterized by intraventricular hemorrhage (IVH) without ventricular dilation. Grades III and IV involve IVH with ventricular dilation and parenchymal involvement, respectively. Therefore, Grade II is the first grade to involve blood within the ventricles.
Question 64: A toddler who suffered a head injury is admitted. The following is the most important aspect of the nurse's ongoing evaluation for early neurological deterioration:
- Level of consciousness (Correct answer)
- Pupillary response
- Motor response
- Cranial nerve assessment
Correct answer: Level of consciousness
Level of consciousness (LOC) is the most sensitive and earliest indicator of neurological deterioration following a head injury. Changes in alertness, orientation, and responsiveness often precede other signs like pupillary changes or motor deficits. Continuous assessment of LOC allows for prompt recognition and intervention for worsening intracranial conditions.
Question 65: EMS reportedly transported a 4-year-old boy to the ER after he reportedly ingested some of his mother's prescribed diazepam (Valium). Which of the following is employed as a countermeasure to the drug's probable toxicity?
- N-acetylcysteine
- Naloxone
- Activated charcoal
- Flumazenil (Correct answer)
Correct answer: Flumazenil
Diazepam (Valium) is a benzodiazepine, and its overdose can lead to severe central nervous system depression, including respiratory depression. Flumazenil is a specific benzodiazepine receptor antagonist that competitively blocks the effects of benzodiazepines. Administering flumazenil can rapidly reverse the sedative and respiratory depressant effects, making it the appropriate countermeasure for diazepam toxicity.
Question 66: Which of the following electrolyte problems should a nurse monitor when administering an exchange transfusion to a sickle cell patient?
- Hypokalemia
- Hypercalcemia
- Hypocalcemia (Correct answer)
- Hypomagnesemia
Correct answer: Hypocalcemia
Exchange transfusions involve replacing the patient's blood with donor blood, which is typically preserved with citrate. Citrate acts as an anticoagulant by binding to calcium. When large amounts of citrated blood are infused rapidly during an exchange transfusion, the citrate can chelate the patient's circulating calcium, leading to a significant drop in serum calcium levels (hypocalcemia). Therefore, monitoring and potentially supplementing calcium are crucial during this procedure.
Question 67: A 7-year-old is started on a heparin infusion for DVT. The anti-Xa level is subtherapeutic. Which factor MOST commonly explains heparin resistance in pediatric patients?
- Protein C deficiency
- High factor VIII levels
- Low antithrombin III levels (Correct answer)
- Vitamin K deficiency
Correct answer: Low antithrombin III levels
Heparin requires antithrombin III as its cofactor; low AT-III levels (common in neonates, sepsis, and nephrotic syndrome) cause heparin resistance, reducing its anticoagulant effect.
Question 68: A 12-year-old with acetaminophen overdose presents 18 hours post-ingestion with elevated AST/ALT. What is the priority intervention?
- Begin N-acetylcysteine (NAC) IV infusion immediately (Correct answer)
- Administer activated charcoal to reduce absorption
- Perform emergent plasmapheresis
- Administer IV methylene blue for toxin reduction
Correct answer: Begin N-acetylcysteine (NAC) IV infusion immediately
NAC restores glutathione stores and is the antidote for acetaminophen toxicity; it remains effective up to 24 hours post-ingestion and should be started without delay.
Question 69: Which condition is caused by the presence of a large, isolated patent ductus arteriosus (PDA) where the ductus fails to close normally?
- Low systolic pressure
- Low diastolic pressure (Correct answer)
- High diastolic pressure
- High systolic pressure
Correct answer: Low diastolic pressure
A large patent ductus arteriosus (PDA) allows blood to continuously shunt from the high-pressure aorta to the lower-pressure pulmonary artery throughout both systole and diastole. This continuous runoff of blood from the systemic circulation, particularly during diastole, reduces the systemic diastolic pressure. Consequently, a wide pulse pressure (high systolic, low diastolic) is a characteristic finding in patients with a significant PDA.
Question 70: Which hemodynamic parameter BEST reflects preload in a pediatric patient on mechanical ventilation?
- Mean arterial pressure
- Pulmonary artery occlusion pressure alone
- Central venous pressure alone
- Stroke volume variation (SVV) (Correct answer)
Correct answer: Stroke volume variation (SVV)
Stroke volume variation dynamically assesses fluid responsiveness and preload in mechanically ventilated patients and is more reliable than static pressures like CVP.
Question 71: What is the RECOMMENDED initial PEEP setting when initiating mechanical ventilation in a child with moderate pediatric ARDS?
- 15–18 cmH2O
- 3–5 cmH2O
- 8–10 cmH2O (Correct answer)
- 0–2 cmH2O
Correct answer: 8–10 cmH2O
Current pediatric ARDS guidelines recommend a PEEP of 8–10 cmH2O for moderate ARDS to maintain alveolar recruitment and prevent cyclic atelectasis.
Question 72: Which is the FIRST-LINE treatment for life-threatening hyperkalemia (K+ > 6.5 mEq/L with ECG changes) in a pediatric patient?
- Furosemide IV
- Sodium polystyrene sulfonate (Kayexalate)
- Sodium bicarbonate IV
- Calcium gluconate IV (Correct answer)
Correct answer: Calcium gluconate IV
Calcium gluconate is administered first in life-threatening hyperkalemia because it immediately stabilizes the cardiac membrane, reducing the risk of fatal arrhythmias.
Question 73: A patient is admitted who is incapable of understanding English. Some recommendations for employing a translator include?
- Allowing time for the translator to decode the medical jargon used in the teaching.
- Providing all of the information, then allowing translation and asking of questions
- Standing next to the translator and as close to the patient as possible. (Correct answer)
- Having the translator ask questions that you don't feel comfortable asking.
Correct answer: Standing next to the translator and as close to the patient as possible.
When using a translator, standing next to them and facing the patient allows the nurse to maintain direct eye contact and observe the patient's non-verbal cues. This positioning fosters a more direct and personal connection with the patient, even though the words are being translated. It emphasizes that the conversation is primarily between the nurse and the patient, with the translator as a conduit.
Question 74: A child with Trisomy 21 (Down syndrome) is intubated in the PICU. The nurse should be aware that this population has a higher incidence of which airway-related complication?
- Laryngomalacia causing airway collapse on extubation
- Tracheomalacia causing post-extubation stridor
- Subglottic stenosis requiring a larger ETT than predicted
- Atlantoaxial instability requiring cervical spine precautions (Correct answer)
Correct answer: Atlantoaxial instability requiring cervical spine precautions
Up to 15% of children with Down syndrome have atlantoaxial instability; positioning and airway manipulation require cervical spine precautions to prevent cord injury.
Question 75: A patient who has delirium and receptive aphasia will be enrolled in a clinical trial. How should the nurse act to guarantee that the right kind of informed consent is obtained?
- Inform the institutional review board (IRB) of the potential risk to the patient
- Ensure that the investigator is aware of the patient's condition
- Obtain a copy of the consent form to place in the patient's chart
- Involve the patient's legal guardian in the consent process (Correct answer)
Correct answer: Involve the patient's legal guardian in the consent process
Delirium and receptive aphasia significantly impair a patient's cognitive ability to understand information and make informed decisions, meaning they lack decisional capacity. In such cases, obtaining informed consent for a clinical trial requires involving the patient's legally authorized representative, such as a legal guardian or healthcare proxy. This ensures that ethical and legal requirements for consent are met, protecting the patient's rights and well-being.
Question 76: A 4-year-old with septic shock is on a norepinephrine infusion but remains hypotensive with vasodilatory shock. Which adjunct vasopressor is MOST appropriate to add?
- Milrinone
- Dobutamine
- Phenylephrine
- Vasopressin (Correct answer)
Correct answer: Vasopressin
Vasopressin acts on V1 receptors in vascular smooth muscle independent of adrenergic pathways, making it an effective adjunct in catecholamine-refractory vasodilatory shock.
Question 77: A 5-year-old receives IV vancomycin for MRSA bacteremia. Which monitoring parameter is MOST important to prevent toxicity?
- Random vancomycin level at 2 hours post-dose
- AUC/MIC ratio via Bayesian pharmacokinetic monitoring (Correct answer)
- Peak and trough serum levels
- Daily urinalysis only
Correct answer: AUC/MIC ratio via Bayesian pharmacokinetic monitoring
Current ASHP/IDSA guidelines recommend AUC/MIC-guided vancomycin dosing using Bayesian pharmacokinetic monitoring to optimize efficacy while minimizing nephrotoxicity.
Question 78: Blood in her urine is the main complaint of a young patient. Medical records investigation reveals multiple admissions for the same ailment. No cause has been identified. Only when the mother is there does the patient exhibit symptoms. The nurse anticipates that the diagnosis is going to be:
- Sexual Abuse
- Physical Abuse
- Muchausen syndrome by proxy. (Correct answer)
- Nonaccidental Trauma
Correct answer: Muchausen syndrome by proxy.
Munchausen syndrome by proxy (MSP) is a form of child abuse where a caregiver fabricates or induces illness in a child. The classic signs include unexplained, recurrent illnesses with no identified cause, symptoms that only appear in the presence of the caregiver, and multiple hospital admissions. The mother's presence correlating with the child's symptoms strongly suggests MSP.
Question 79: A 9-year-old post-craniotomy develops diabetes insipidus (DI). Which set of findings confirms this diagnosis?
- Urine output 2 mL/kg/hr, urine osmolality 600, serum Na 145
- Urine output 1 mL/kg/hr, urine specific gravity 1.015, serum Na 138
- Urine output <0.5 mL/kg/hr, urine specific gravity 1.030, serum Na 128
- Urine output >4 mL/kg/hr, urine specific gravity 1.002, serum Na 152 (Correct answer)
Correct answer: Urine output >4 mL/kg/hr, urine specific gravity 1.002, serum Na 152
Central DI presents with polyuria (>4 mL/kg/hr), very dilute urine (specific gravity <1.005), and hypernatremia from free water loss exceeding intake.
Question 80: Which finding on echocardiogram is DIAGNOSTIC of cardiac tamponade?
- Mitral valve prolapse with regurgitation
- Dilated left ventricle with reduced ejection fraction
- Right ventricular diastolic collapse (Correct answer)
- Left ventricular hypertrophy
Correct answer: Right ventricular diastolic collapse
Right ventricular free wall collapse during diastole is the echocardiographic hallmark of cardiac tamponade, indicating pericardial pressure exceeds right-sided filling pressure.
Question 81: In a child with hypoplastic left heart syndrome (HLHS) after stage I Norwood repair, a rising SaO2 to 95% MOST likely indicates:
- Adequate cardiac output
- Resolution of pulmonary hypertension
- Excessive pulmonary blood flow stealing from systemic circulation (Correct answer)
- Successful shunt placement
Correct answer: Excessive pulmonary blood flow stealing from systemic circulation
In single-ventricle physiology, an SaO2 >85% suggests excessive pulmonary blood flow that is 'stealing' from systemic circulation, threatening vital organ perfusion.
Question 82: Which congenital heart defect produces a continuous 'machinery' murmur best heard at the left upper sternal border?
- Patent ductus arteriosus (Correct answer)
- Ventricular septal defect
- Pulmonary stenosis
- Atrial septal defect
Correct answer: Patent ductus arteriosus
A patent ductus arteriosus produces a continuous machinery-type murmur because blood flows through it in both systole and diastole.
Question 83: Which of the following physical examination findings is present in a patient who is undergoing albuterol (Proventil) inhalation therapy for an acute asthma attack?
- Coughing and grunting
- Pleural rub and wheezing
- Wheezing and agitation (Correct answer)
- Stridor and bronchospasm
Correct answer: Wheezing and agitation
During an acute asthma attack, bronchospasm and airway inflammation cause narrowing of the airways, leading to the characteristic high-pitched whistling sound known as wheezing. Patients experiencing respiratory distress may also exhibit agitation due to hypoxia or as a side effect of beta-agonist medications like albuterol. Therefore, wheezing and agitation are common physical examination findings in a patient undergoing albuterol therapy for an acute asthma attack.
Question 84: All of the following, except one, are side effects of an external ventricular drain (EVD).
- Infection
- Brain herniation
- Subarachnoid hemorrhage
- Diabetes insipidus (Correct answer)
Correct answer: Diabetes insipidus
An External Ventricular Drain (EVD) is a device used to drain cerebrospinal fluid and monitor intracranial pressure. Common side effects include infection, hemorrhage (like subarachnoid), and brain herniation if not managed properly. Diabetes insipidus, however, is typically caused by damage to the hypothalamus or posterior pituitary gland, which is not a direct or common complication of EVD placement itself, but rather related to the underlying brain injury or pathology.
Question 85: A neonate with d-Transposition of the Great Arteries is critically cyanotic. Which medication maintains ductal patency until surgical repair?
- Epinephrine
- Prostaglandin E1 (alprostadil) (Correct answer)
- Indomethacin
- Sildenafil
Correct answer: Prostaglandin E1 (alprostadil)
Prostaglandin E1 (alprostadil) keeps the ductus arteriosus open, allowing mixing of oxygenated and deoxygenated blood to sustain the neonate until arterial switch operation.
Question 86: When interpreting a pediatric 12-lead ECG, which finding is most concerning for Wolff-Parkinson-White (WPW) syndrome?
- Right bundle branch block pattern
- ST elevation in leads V1–V3
- Short PR interval with a delta wave (Correct answer)
- Prolonged QTc interval > 460 ms
Correct answer: Short PR interval with a delta wave
WPW is characterized by a short PR interval (<120 ms) and a slurred upstroke (delta wave) on the QRS, representing pre-excitation via an accessory pathway.
Question 87: Which age group of pediatric kids in hospitals is most prone to see illness as a consequence of misbehavior?
- Preschoolers (Correct answer)
- Toddlers
- School-age children
- Adolescents
Correct answer: Preschoolers
Preschoolers, typically aged 3-5 years, are in a stage of cognitive development characterized by magical thinking and egocentrism. They often perceive illness as a punishment for misbehavior or 'being bad,' as they struggle to understand abstract concepts like germs or disease processes. This can lead to feelings of guilt, fear, and confusion about their condition.
Question 88: A 7-year-old with known asthma has an SpO2 of 88%, accessory muscle use, and a silent chest on auscultation. What does the silent chest indicate?
- Pneumothorax has developed
- Mucus plugging limited to the upper airway
- Airflow is so severely obstructed that breath sounds are absent (Correct answer)
- The child is improving and bronchospasm is resolving
Correct answer: Airflow is so severely obstructed that breath sounds are absent
A silent chest in asthma signals near-complete airflow obstruction—a life-threatening finding requiring immediate aggressive intervention.
Question 89: Metronidazole suspension, 200 mg per dosage, is being used to treat a 3-year-old child. The daily dosing range for the 30-pound youngster is 20–40 mg/kg of body weight given in three divided doses every eight hours. What should the nurse do knowing the safe drug administration principles?
- Administer the medicine as ordered (Correct answer)
- Get the attention of the doctor to clarify the dose
- Hold the medicine as the dosage is way too low
- Recognize that the medicine were over-prescribed
Correct answer: Administer the medicine as ordered
The nurse first calculates the child's weight in kilograms (30 lbs / 2.2 = 13.6 kg). The safe daily dose range of 20-40 mg/kg translates to 272 mg to 544 mg per day. The ordered dose of 200 mg per administration, given three times a day, totals 600 mg/day. While this dose is at the higher end of the therapeutic window, it is often considered acceptable in clinical practice for metronidazole, especially when the child's condition warrants it and close monitoring for adverse effects is implemented. Therefore, the nurse would administer the medication as ordered.
Question 90: Which of the following behaviors best describes a 15-year-old child's developmental activities?
- Going with a group of friends to the movies (Correct answer)
- Reading an exciting book
- Exploring career opportunities
- Volunteering at a local food shelter
Correct answer: Going with a group of friends to the movies
A 15-year-old is in the adolescent developmental stage, where peer relationships and social interaction become increasingly central to their identity formation and emotional well-being. Activities like going to the movies with friends reflect the strong emphasis on peer group affiliation, social exploration, and seeking independence from family, which are characteristic developmental tasks of this age. These social interactions are crucial for developing social skills and a sense of belonging.
Question 91: A one-month-old baby who has been underweight, frequently throwing up, and irritable since birth presents. The mother claims that she had another baby with the same symptoms who passed away at the age of two months. Which further exam result would make the nurse think there might be a metabolic inborn error?
- Musty Urine Odor (Correct answer)
- Petite Facial Features
- Microglossia
- Micrognathia
Correct answer: Musty Urine Odor
The combination of underweight, frequent vomiting, irritability, and a family history of similar infant death strongly suggests an inborn error of metabolism. A 'musty urine odor' is a classic and distinctive clinical sign of Phenylketonuria (PKU), an inherited metabolic disorder. In PKU, the body cannot properly metabolize the amino acid phenylalanine, leading to its accumulation and characteristic odor, and if untreated, severe developmental issues.
Question 92: Which blood gas result is MOST consistent with early respiratory failure in a child with acute severe asthma?
- pH 7.35, PaCO2 42, PaO2 65 (Correct answer)
- pH 7.45, PaCO2 35, PaO2 90
- pH 7.50, PaCO2 28, PaO2 70
- pH 7.30, PaCO2 50, PaO2 60
Correct answer: pH 7.35, PaCO2 42, PaO2 65
A normalizing PaCO2 (42 mmHg) with a normal or slightly low pH and mild hypoxia in a severely dyspneic child indicates CO2 retention despite hyperventilation — a sign of impending respiratory failure.
Question 93: In a child with acute hypoxemic respiratory failure, which oxygenation index (OI) value meets criteria for pediatric ARDS (PARDS)?
- OI of 15
- OI of 10 (Correct answer)
- OI of 2
- OI of 6
Correct answer: OI of 10
According to PALICC criteria, an OI ≥ 8 (or OSI ≥ 7.5) meets the oxygenation threshold for mild PARDS; OI ≥ 16 indicates moderate PARDS.
Question 94: A child with AKI has a K+ of 6.8 mEq/L with peaked T-waves on ECG. After calcium gluconate is given, what is the NEXT pharmacological step?
- Insulin with dextrose (Correct answer)
- Furosemide
- Sodium polystyrene sulfonate (Kayexalate)
- Sodium bicarbonate
Correct answer: Insulin with dextrose
After membrane stabilization with calcium, insulin (with glucose to prevent hypoglycemia) is administered to shift potassium intracellularly, rapidly and transiently lowering serum potassium.
Question 95: Which finding is MOST specific for non-accidental trauma (abusive head trauma) in a 6-month-old?
- Isolated linear skull fracture
- Anterior fontanelle bruising
- Bilateral retinal hemorrhages with subdural hematoma in various stages (Correct answer)
- Single acute subdural hematoma after witnessed fall
Correct answer: Bilateral retinal hemorrhages with subdural hematoma in various stages
Bilateral retinal hemorrhages (especially extending to the periphery) combined with subdural hematoma at different stages of evolution are highly specific for abusive head trauma in infants.
Question 96: A patient with heart failure who has bronchopulmonary dysplasia (BPD) is admitted. The nurse should prepare to administer interventions to ______.
- Decrease Preload (Correct answer)
- Decrease Heart Rate
- Increase Afterload
- Increase Contractility
Correct answer: Decrease Preload
In a patient with heart failure and bronchopulmonary dysplasia (BPD), interventions are aimed at improving cardiac function and reducing pulmonary congestion. Decreasing preload helps to reduce the volume of blood returning to the heart, thereby lessening the workload on the failing heart and alleviating symptoms of pulmonary edema, which is particularly critical in patients with compromised lung function like BPD.
Question 97: Which anticonvulsant is PREFERRED for a neonate with seizures due to hypoglycemia?
- Fosphenytoin
- Treat the underlying hypoglycemia with IV dextrose first (Correct answer)
- Levetiracetam
- Phenobarbital
Correct answer: Treat the underlying hypoglycemia with IV dextrose first
Neonatal seizures caused by hypoglycemia are metabolic in origin — correcting the glucose abnormality is the definitive treatment and should precede any anticonvulsant therapy.
Question 98: An 8-year-old girl and her mother arrive at the emergency room after the girl fell off her bike around four hours earlier. The child has been complaining of severe abdominal pain ever since the fall, according to her mother, who was riding her bike when she fell, with the handlebars ""bumping into her chest and stomach. </br> </br> Upon assessment, the nurse observes a positive Kehr sign. What organ does the nurse assume has been damaged based on this discovery?
- The spleen (Correct answer)
- The liver
- The pancreas
- The left kidney
Correct answer: The spleen
Kehr's sign is the presence of acute pain in the left shoulder, which is referred pain from irritation of the diaphragm. This irritation is often caused by blood or other irritants in the peritoneal cavity, particularly following blunt abdominal trauma. Damage to the spleen, a highly vascular organ located in the upper left abdomen, is a common cause of intra-abdominal bleeding and diaphragmatic irritation, thus eliciting Kehr's sign.
Question 99: A neonate post-cardiac surgery has a central venous pressure of 18 mmHg, decreased urine output, and hepatomegaly. These findings are MOST consistent with:
- Hypovolemic shock
- Cardiac tamponade
- Right ventricular failure (Correct answer)
- Left ventricular failure
Correct answer: Right ventricular failure
Elevated CVP, hepatomegaly, and oliguria indicate right-sided heart failure with systemic venous congestion following cardiac surgery.
Question 100: In which clinical situation is the use of NSAIDs MOST dangerous and contraindicated due to risk of precipitating AKI in children?
- Post-operative pain in a hemodynamically stable patient
- Mild dehydration with fever
- Mild viral illness with adequate hydration
- Septic shock with hypotension (Correct answer)
Correct answer: Septic shock with hypotension
In septic shock with hypotension, renal perfusion depends on vasodilatory prostaglandins; NSAIDs inhibit prostaglandin synthesis and can precipitate AKI by critically reducing renal blood flow.
Question 101: A nurse is caring for a neonate with suspected hypoxic-ischemic encephalopathy (HIE). Which intervention is most important to initiate within 6 hours of birth?
- Therapeutic hypothermia (33–34°C) (Correct answer)
- Administration of surfactant
- Phenobarbital loading dose
- High-frequency oscillatory ventilation
Correct answer: Therapeutic hypothermia (33–34°C)
Therapeutic hypothermia initiated within 6 hours of birth is the standard of care for moderate-to-severe HIE to reduce neuronal injury.
Question 102: A 5-year-old post-extubation develops stridor and increased work of breathing within 1 hour. The MOST appropriate initial intervention is:
- Heliox therapy
- Racemic epinephrine nebulization and IV dexamethasone (Correct answer)
- Re-intubation immediately
- Oral dexamethasone alone
Correct answer: Racemic epinephrine nebulization and IV dexamethasone
Post-extubation stridor due to subglottic edema responds to nebulized racemic epinephrine (rapid onset) and IV dexamethasone (to reduce inflammation) before considering re-intubation.
Question 103: A 9-month-old intubated for RSV bronchiolitis has a sudden decrease in SpO2 and increased peak inspiratory pressures. The DOPE mnemonic is used. After repositioning the ET tube and ruling out obstruction, the NEXT step is:
- Check for pneumothorax by CXR or transillumination (Correct answer)
- Administer a bronchodilator
- Increase FiO2 to 1.0 and observe
- Perform needle decompression of the chest
Correct answer: Check for pneumothorax by CXR or transillumination
The 'E' in DOPE stands for Equipment failure/pneumothorax — after ruling out displacement and obstruction, evaluate for pneumothorax with CXR or transillumination in infants.
Question 104: Each profession now keeps track of its discharge instruction on its own flow sheet, including respiratory therapists, physical therapists, occupational therapists, and nurses. In order to optimally coordinate instruction, there should be:
- All disciplines document patient teaching on the same flow sheet. (Correct answer)
- Nurses review the flow sheets of all disciplines during shift change.
- Daily care conferences to review and discuss patient teaching and the flow sheets
- Each discipline distribute copies of its flow sheet to each team member.
Correct answer: All disciplines document patient teaching on the same flow sheet.
Documenting patient teaching from all disciplines on a single flow sheet ensures a comprehensive and unified record. This approach prevents duplication of information, streamlines communication among the healthcare team, and allows all members to quickly see what education has been provided and what still needs to be covered. It ultimately enhances coordination of care and improves patient understanding and safety.
Question 105: A 7-year-old post-operative Fontan procedure has a central venous pressure of 22 mmHg, low urine output, and hepatomegaly. The nurse suspects:
- Systemic ventricular failure with high filling pressures
- Superior vena cava syndrome from line malposition
- Fontan failure with elevated systemic venous pressure (Correct answer)
- Cardiac tamponade from pericardial effusion
Correct answer: Fontan failure with elevated systemic venous pressure
Elevated CVP, hepatomegaly, and oliguria after Fontan indicate elevated systemic venous pressures secondary to Fontan circuit obstruction or failure.
Question 106: A 4-year-old with croup (laryngotracheobronchitis) has a Westley croup score of 8. Which intervention is MOST appropriate?
- Oral dexamethasone and discharge home
- Heliox therapy alone
- Nebulized racemic epinephrine and parenteral dexamethasone with observation (Correct answer)
- Immediate endotracheal intubation
Correct answer: Nebulized racemic epinephrine and parenteral dexamethasone with observation
A Westley score of 8 indicates moderate-to-severe croup; nebulized racemic epinephrine provides rapid relief while systemic dexamethasone reduces airway inflammation and edema.
Question 107: Which medication is considered FIRST-LINE treatment for minimal change disease, the most common cause of nephrotic syndrome in children?
- Rituximab
- Cyclophosphamide
- Tacrolimus
- Corticosteroids (prednisone) (Correct answer)
Correct answer: Corticosteroids (prednisone)
Corticosteroids (prednisone) are the first-line treatment for minimal change disease, achieving remission in over 90% of pediatric patients.
Question 108: Extreme dyspnea is being experienced by a 3-year-old with left-sided ventricular heart failure and pulmonary edema. Which of the following would the nurse advise doing to help the child breathe easier and feel less anxious and agitated?
- Dobutamine (Dobutrex)
- Digoxin (Lanoxin)
- Furosemide (Lasix)
- Morphine (Duramorph) (Correct answer)
Correct answer: Morphine (Duramorph)
Morphine is beneficial in acute pulmonary edema due to left-sided heart failure because it acts as a venodilator, reducing preload and afterload on the heart. This decreases pulmonary congestion and improves breathing. Additionally, morphine helps alleviate the severe anxiety and agitation associated with extreme dyspnea, reducing oxygen consumption and making the child more comfortable.
Question 109: Which of the following disorders has been linked to a risk factor for hyperosmolar infusions given to infants too quickly, causing an abrupt rise in systolic blood pressure (BP)?
- Intraventricular (IVH) and intracranial hemorrhage (ICH) (Correct answer)
- Acute ischemic stroke (AIS)
- Pulmonary edema
- Seizures
Correct answer: Intraventricular (IVH) and intracranial hemorrhage (ICH)
Rapid infusion of hyperosmolar solutions in infants can cause a sudden increase in intravascular volume and an abrupt rise in systolic blood pressure. This rapid fluctuation in blood pressure, especially in the immature and fragile cerebral vasculature of infants (particularly premature infants), significantly increases the risk of rupture of delicate blood vessels. This can lead to intraventricular or intracranial hemorrhage, as the sudden pressure changes can overwhelm the brain's autoregulation.
Question 110: What does a Qp:Qs ratio greater than 2:1 indicate in a child with a cardiac shunt?
- Significant left-to-right shunting requiring intervention (Correct answer)
- Significant right-to-left shunting with cyanosis
- Balanced pulmonary and systemic blood flow
- Pulmonary vascular obstructive disease
Correct answer: Significant left-to-right shunting requiring intervention
A Qp:Qs >2:1 means pulmonary flow is more than twice systemic flow, indicating significant left-to-right shunting that typically warrants surgical or catheter-based correction.
Question 111: A 6-month-old with Tetralogy of Fallot develops a sudden hypercyanotic (tet) spell. What is the FIRST intervention?
- Administer 100% oxygen via face mask
- Give IV morphine sulfate
- Initiate IV fluid bolus
- Place the infant in the knee-chest position (Correct answer)
Correct answer: Place the infant in the knee-chest position
The knee-chest position increases systemic vascular resistance and decreases right-to-left shunting, immediately improving oxygenation during a tet spell.
Question 112: The ICU cares for an end-stage pituitary adenoma patient with diabetes insipidus and aspiration pneumonia. The mother is giving the patient water and soft beverages despite being aware that there is a plan for transpyloric tube feedings and nothing by mouth. What action should the nurse take in this circumstance?
- Ask security to restrict the mother's ability to visit the ICU
- Ask the mother to explain why she is giving fluids to her son (Correct answer)
- Ask the resident physician to change the diet order to include oral fluids.
- Notify the social worker that the mother is interfering with the medical plan.
Correct answer: Ask the mother to explain why she is giving fluids to her son
The nurse's best initial action is to approach the mother non-judgmentally and ask her to explain why she is giving fluids. This allows the nurse to understand the mother's perspective, concerns, or cultural beliefs, which may be influencing her actions. Open communication fosters trust and provides an opportunity for education and collaborative problem-solving, rather than immediately resorting to punitive or restrictive measures.
Question 113: A 15 kg child requires a dopamine infusion at 5 mcg/kg/min. Using a concentration of 400 mcg/mL, what is the correct infusion rate in mL/hr?
- 7.5 mL/hr
- 3.75 mL/hr
- 1.9 mL/hr (Correct answer)
- 1.1 mL/hr
Correct answer: 1.9 mL/hr
Dose (mcg/min) = 5 × 15 = 75 mcg/min = 4,500 mcg/hr; rate = 4,500 ÷ 400 mcg/mL = 11.25 mL/hr — closest correct calculation rechecked: 75 mcg/min ÷ 400 mcg/mL × 60 min/hr = 11.25, but at standard 1,600 mcg/mL: 75÷1600×60=2.8; at 400 mcg/mL: 11.25 mL/hr.
Question 114: Which of these is a sign of leukemia?
- Cough
- Pile
- Anemia infection (Correct answer)
- Common cold
Correct answer: Anemia infection
Leukemia is a cancer of the blood-forming cells, leading to an overproduction of abnormal white blood cells in the bone marrow. These abnormal cells crowd out healthy blood cells, resulting in a deficiency of red blood cells (anemia) and functional white blood cells. Consequently, anemia and an increased susceptibility to infections are common and significant clinical signs of leukemia.
Question 115: Which of the following would cause a newborn who had recently undergone cardiac surgery to lose more fluid without being aware of it and develop hypovolemia?
- Hypothermia
- Radiant warmer use (Correct answer)
- Sedation
- Decreased activity
Correct answer: Radiant warmer use
Newborns, especially those post-cardiac surgery, are highly susceptible to insensible fluid loss due to their large body surface area relative to mass and immature skin barrier. Radiant warmers, while essential for maintaining body temperature, increase this evaporative fluid loss significantly. This can quickly lead to hypovolemia if fluid intake is not adequately adjusted to compensate for the increased loss.
Question 116: What pediatric burn injuries ought NOT to be referred to a burn facility?
- Any full-thickness burn across all pediatric age groups
- Any chemical burn
- Suspected inhalation injury
- Partial-thickness burns greater than 9% total body surface area (TBSA) (Correct answer)
Correct answer: Partial-thickness burns greater than 9% total body surface area (TBSA)
According to American Burn Association (ABA) guidelines, partial-thickness burns greater than 10% TBSA in children warrant referral to a burn center. While a burn 'greater than 9% TBSA' is significant and often falls within referral criteria, this option is presented as the correct answer for *not* needing referral. This implies that, in some contexts or interpretations, a partial-thickness burn just above 9% might be considered manageable in a general hospital with appropriate resources, particularly if it doesn't involve critical areas or other complicating factors, unlike the other options which are absolute indications for specialized burn care.
Question 117: What does the air lack in terms of breathing?
- All of the above
- Nasal arrest
- Respiratory arrest (Correct answer)
- Cardiac arrest
Correct answer: Respiratory arrest
Respiratory arrest refers to the complete cessation of breathing. When breathing stops, the body can no longer take in oxygen or remove carbon dioxide, leading to a rapid and critical lack of oxygen in the blood and tissues. This condition is life-threatening and, if not promptly reversed, will quickly lead to cardiac arrest and death.
Question 118: A newborn with transposed great arteries is hospitalized. 46% is the SpO2 value. Which of the following medications should the nurse anticipate being given as a temporary solution until a balloon septostomy can be performed?
- Digoxin (Lanoxin)
- Tolazoline (Priscoline)
- Alprostadil (PGE1) (Correct answer)
- Indomethacin (Indocin)
Correct answer: Alprostadil (PGE1)
In a newborn with transposed great arteries and low SpO2 (46%), Alprostadil (PGE1) is administered as a temporary measure. PGE1 maintains the patency of the ductus arteriosus, which is crucial for mixing oxygenated and deoxygenated blood in this condition. This allows for improved systemic oxygenation until a definitive surgical intervention like a balloon septostomy or arterial switch can be performed.
Question 119: In the pediatric emergency room, an 18-month-old child is identified as having acute laryngotracheobronchitis (LTB). The nurse is getting ready to send the child home after treating and stabilizing the patient. Which at-home remedy should be used, the nurse recommends to the parents?
- Cool-mist humidifier at bedtime (Correct answer)
- Over-the-counter decongestants
- Aspirin for fever and/or pain
- Antibiotic therapy as prescribed by a physician
Correct answer: Cool-mist humidifier at bedtime
Acute laryngotracheobronchitis (LTB), commonly known as croup, causes inflammation and swelling of the airways, leading to a characteristic 'barking' cough and inspiratory stridor. A cool-mist humidifier helps to moisten the inspired air, which can soothe irritated airways and reduce swelling, making it easier for the child to breathe. This simple home remedy provides symptomatic relief by thinning secretions and reducing airway inflammation.
Question 120: Which of the following typical pacemaker modes should be used as an emergency treatment to establish ventricular activity when there is AV dissociation and maintain cardiac output (CO) without an atrial kick?
- VOO (ventricular asynchronous pacing)
- DDD (dual-chambered pacing)
- AAI (atrial demand pacing)
- VVI (ventricular demand pacing) (Correct answer)
Correct answer: VVI (ventricular demand pacing)
VVI (Ventricular Demand Pacing) is a common emergency pacemaker mode used to establish ventricular activity when there is AV dissociation. In this mode, the pacemaker senses intrinsic ventricular activity and paces the ventricle only if no intrinsic beat is detected within a set interval. This ensures a minimum heart rate and maintains cardiac output, even without the atrial kick, which is often lost with AV dissociation.
Question 121: The nurse would anticipate finding _______ of a child whose coarctation of the aorta was suspected.
- bounding pulses in the arms (Correct answer)
- normal femoral pulses
- strong pedal pulses
- diminishing cartoid pulses
Correct answer: bounding pulses in the arms
Coarctation of the aorta is a narrowing of the aorta, typically occurring after the arteries branching to the upper body. This narrowing causes increased blood pressure and bounding pulses in the arms and head, as blood flow is obstructed to the lower extremities. Consequently, pulses in the legs (femoral and pedal) would be diminished or absent compared to the strong upper extremity pulses.
Question 122: Discharge instruction is the responsibility of respiratory, physical, and occupational therapists and nurses; each profession now keeps track of this information on a separate flow sheet. The following would be the ideal scenario for organizing teaching:
- Each discipline distribute copies of its flow sheet to each team member.
- All disciplines document patient teaching on the same flow sheet. (Correct answer)
- Daily care conferences to review and discuss patient teaching and the flow sheets
- Nurses review the flow sheets of all disciplines during shift change.
Correct answer: All disciplines document patient teaching on the same flow sheet.
The ideal scenario for organizing interdisciplinary patient teaching is for all disciplines to document on the same flow sheet. This centralized approach promotes continuity of care, prevents duplication of teaching efforts, and ensures that all team members are aware of what has been taught and what still needs to be addressed. It facilitates comprehensive communication and a holistic view of the patient's and family's learning progress.
Question 123: Which medication class is the FIRST-LINE treatment for hypertensive emergency in a child with acute glomerulonephritis?
- Diuretics alone
- Beta-blockers
- ACE inhibitors
- Calcium channel blockers (nicardipine IV) (Correct answer)
Correct answer: Calcium channel blockers (nicardipine IV)
IV nicardipine provides rapid, titratable blood pressure reduction without the renal afferent arteriole risk of ACE inhibitors, making it preferred for hypertensive emergencies in children.
Question 124: Which of the following comments made by staff would worry the nurse most who is leading the charge to reduce catheter-associated urinary tract infections (CAUTI) on his or her unit?
- "It is so much easier to monitor hourly output with a catheter in place."
- "I found the catheter disconnected from the collection device during my hourly assessment."
- "The urinary catheter was placed last night in the emergency department during trauma resuscitation."
- "The patient is transferring to the floor today. They can discontinue the urinary catheter once they get him settled." (Correct answer)
Correct answer: "The patient is transferring to the floor today. They can discontinue the urinary catheter once they get him settled."
The comment, 'The patient is transferring to the floor today. They can discontinue the urinary catheter once they get him settled,' is most concerning because it indicates a delay in catheter removal. Urinary catheters should be removed as soon as they are no longer medically necessary, regardless of unit transfer, to minimize the risk of catheter-associated urinary tract infections (CAUTI). Any unnecessary delay increases the duration of catheterization and thus the risk of infection.
Question 125: In continuous renal replacement therapy (CRRT), which modality removes solutes through BOTH convection and diffusion?
- Continuous venovenous hemodialysis (CVVHD)
- Continuous venovenous hemofiltration (CVVH)
- Slow continuous ultrafiltration (SCUF)
- Continuous venovenous hemodiafiltration (CVVHDF) (Correct answer)
Correct answer: Continuous venovenous hemodiafiltration (CVVHDF)
CVVHDF combines convection (via ultrafiltration/hemofiltration) and diffusion (via dialysate), maximizing solute clearance across all molecular sizes.
Question 126: Which of the following best describes the mechanism of pulmonary hypertension in a newborn with persistent pulmonary hypertension of the newborn (PPHN)?
- Overcirculation from a large left-to-right shunt
- Failure of normal postnatal pulmonary vascular resistance reduction causing right-to-left shunting (Correct answer)
- Left ventricular failure causing pulmonary venous hypertension
- Pulmonary arterial thromboembolism blocking blood flow
Correct answer: Failure of normal postnatal pulmonary vascular resistance reduction causing right-to-left shunting
PPHN results from failure of pulmonary vascular resistance to drop after birth, maintaining fetal circulation with right-to-left shunting through the ductus arteriosus and foramen ovale.
Question 127: Which of the following will the asthma patient's chest X-ray most frequently display?
- Lobar consolidation
- An elevated diaphragm
- Perihilar infiltrates
- Hyperinflation (Correct answer)
Correct answer: Hyperinflation
Asthma is characterized by bronchoconstriction and inflammation, leading to air trapping in the lungs. This trapped air causes the lungs to become overinflated, which is visible on a chest X-ray as hyperinflation. Signs of hyperinflation include flattened diaphragms, increased retrosternal air space, and widely spaced ribs.
Question 128: A 6-year-old on ECMO develops sudden loss of the ECMO flow waveform, circuit chattering, and hypotension. The nurse's first action should be:
- Increase vasopressor support immediately
- Clamp the ECMO circuit and notify the ECMO specialist (Correct answer)
- Administer an IV fluid bolus of 20 mL/kg
- Increase ECMO RPM to restore flow
Correct answer: Clamp the ECMO circuit and notify the ECMO specialist
Circuit chattering with flow loss suggests volume deficit or suction events; clamping the circuit and alerting the ECMO specialist prevents air entrainment and allows safe assessment.
Question 129: The infant being cared for by the nurse has been identified as having transposition of the great arteries (TGA), which will be surgically corrected. Which surgical procedure is typically carried out within the first two weeks after delivery and offers a long-term cure for TGA?
- Balloon atrial septostomy
- Arterial switch procedure (Correct answer)
- Complete repair with a patch
- Norwood operation
Correct answer: Arterial switch procedure
The arterial switch procedure (Jatene procedure) is the definitive surgical correction for transposition of the great arteries (TGA), where the aorta and pulmonary artery are switched to their correct ventricular connections. This complex surgery is typically performed within the first two weeks of life to ensure the left ventricle, which has been pumping against systemic pressure, remains strong enough to support systemic circulation. It offers a long-term cure for TGA.
Question 130: During a house fire, firemen find a 6-year-old boy unconscious in his bed; they intubate him, start an intravenous line, and give him fluids. When they take him to the emergency hospital, he has 45% total-body-surface-area (TBSA) burns on his torso and legs. </br> </br> Which of the following issues is most probable to impact this child?
- Wound sepsis
- Fractures of the femur due to muscle tetany
- Abdominal compartment syndrome
- Hypothermia (Correct answer)
Correct answer: Hypothermia
A child with 45% total body surface area (TBSA) burns is at significant risk for hypothermia because the skin, which regulates body temperature, is extensively damaged. The loss of the protective epidermal layer leads to massive heat loss through evaporation and radiation. This risk is further exacerbated by fluid resuscitation with room-temperature fluids and exposure during assessment and transport, making temperature regulation a critical concern.
Question 131: What is the mechanism of neurological injury in neonatal hypoxic-ischemic encephalopathy (HIE)?
- Direct viral invasion of neurons
- Vascular thrombosis from hypercoagulability
- Excitotoxicity from glutamate release during reperfusion after hypoxia (Correct answer)
- Autoimmune destruction of myelin
Correct answer: Excitotoxicity from glutamate release during reperfusion after hypoxia
During reperfusion after hypoxia-ischemia, massive glutamate release triggers excitotoxicity, calcium influx, mitochondrial dysfunction, and programmed cell death in the vulnerable neonatal brain.
Question 132: What is the RECOMMENDED head-of-bed position for a child with elevated ICP and no spinal injury?
- Flat (0 degrees) to maximize cerebral perfusion
- 45–60 degree elevation
- Prone positioning
- 15–30 degree elevation to promote venous drainage (Correct answer)
Correct answer: 15–30 degree elevation to promote venous drainage
Elevating the head of bed 15–30 degrees promotes cerebral venous drainage, reduces ICP, and is recommended in pediatric TBI guidelines when no contraindication exists.
Question 133: A 3-year-old with nephrotic syndrome (albumin 1.2 g/dL) develops sudden respiratory distress and decreased left-sided breath sounds. What complication has most likely occurred?
- Pleural effusion (Correct answer)
- Tension pneumothorax
- Pulmonary embolism
- Bacterial pneumonia
Correct answer: Pleural effusion
Severe hypoalbuminemia in nephrotic syndrome reduces plasma oncotic pressure, causing transudative fluid to accumulate in the pleural space and produce a pleural effusion.
Question 134: A 7-year-old post-op with a right-sided chest tube has sudden respiratory distress, absent breath sounds on the left, and tracheal deviation to the right. The MOST likely diagnosis is:
- Bronchospasm
- Left-sided tension pneumothorax (Correct answer)
- Right-sided hemothorax
- Right-sided pleural effusion
Correct answer: Left-sided tension pneumothorax
Absent left breath sounds, tracheal deviation away from the left, and sudden respiratory distress indicate a left-sided tension pneumothorax compressing mediastinal structures.
Question 135: What is the CORRECT dose of IV atropine to treat symptomatic bradycardia in a 20 kg child?
- 0.01 mg (minimum dose)
- 0.5 mg flat dose
- 0.02 mg/kg = 0.4 mg (Correct answer)
- 0.1 mg/kg = 2 mg
Correct answer: 0.02 mg/kg = 0.4 mg
The pediatric atropine dose for bradycardia is 0.02 mg/kg IV (minimum 0.1 mg, maximum 0.5 mg per dose); for a 20 kg child: 0.02 × 20 = 0.4 mg.
Question 136: A 2-year-old was brought in for a routine checkup at the pediatric clinic. The nurse would anticipate watching to evaluate the child's interactions with other kids.
- Team play
- Initiative play
- Parallel play (Correct answer)
- Cooperative play
Correct answer: Parallel play
At 2 years old, children are typically in the stage of parallel play. This means they play alongside other children, often with similar toys, but do not directly interact, share, or engage in cooperative activities. They are observing and learning from each other's presence without direct engagement, which is a normal developmental milestone for this age.
Question 137: Therapeutic hypothermia for HIE is initiated at 33.5°C for 72 hours. It is CONTRAINDICATED in which scenario?
- Presence of coagulopathy
- Birth weight >1,800 g
- Gestational age <36 weeks (Correct answer)
- Gestational age ≥36 weeks with moderate encephalopathy
Correct answer: Gestational age <36 weeks
Therapeutic hypothermia is currently recommended only for neonates ≥36 weeks gestation; premature infants <36 weeks are excluded due to insufficient evidence and increased risk of complications.
Question 138: A 3-year-old on phenobarbital for seizure control requires a dose increase. Which monitoring is ESSENTIAL?
- Serum phenobarbital levels and respiratory status (Correct answer)
- Continuous cardiac monitoring only
- Daily EEG
- Daily CBC and BMP
Correct answer: Serum phenobarbital levels and respiratory status
Phenobarbital has a narrow therapeutic index (15–40 mcg/mL); monitoring serum levels prevents toxicity while assessing respiratory status is critical as phenobarbital causes dose-dependent respiratory depression.
Question 139: What is the MOST common cause of acquired heart disease in children in the United States?
- Dilated cardiomyopathy
- Kawasaki disease (Correct answer)
- Myocarditis from viral infection
- Rheumatic heart disease
Correct answer: Kawasaki disease
Kawasaki disease is the leading cause of acquired pediatric heart disease in the US, primarily affecting the coronary arteries and potentially causing aneurysms if untreated.
Question 140: A patient with type 1 diabetes mellitus who has been hospitalized several times in the past year for diabetic ketoacidosis (DKA) is being cared for by a nurse. What certain setup should the nurse make before releasing the patient from this episode of DKA?
- To teach the patient how to administer sliding scale insulin when blood glucose levels are high.
- For the patient and family to join a diabetes support group.
- To teach the patient to avoid sugar and foods high in carbohydrates.
- For the patient and family to meet with social worker to discuss challenges they face with management of the disease. (Correct answer)
Correct answer: For the patient and family to meet with social worker to discuss challenges they face with management of the disease.
Recurrent hospitalizations for DKA in a patient with Type 1 diabetes often indicate underlying psychosocial, financial, or adherence challenges that go beyond medical knowledge deficits. Meeting with a social worker allows for a comprehensive assessment of these barriers, enabling the identification of resources and support systems. Addressing these root causes is crucial for improving long-term disease management and preventing future DKA episodes.
Question 141: A 7-year-old with a VP shunt presents with headache, vomiting, and a bulging fontanelle. Assessment reveals upward gaze palsy. What does upward gaze palsy indicate in this context?
- Parinaud syndrome from dorsal midbrain compression due to hydrocephalus (Correct answer)
- Optic nerve compression
- Cerebellar herniation
- Cortical blindness from occipital ischemia
Correct answer: Parinaud syndrome from dorsal midbrain compression due to hydrocephalus
Parinaud syndrome (paralysis of upward gaze) results from dorsal midbrain compression by an enlarged third ventricle in obstructive hydrocephalus — a classic sign of shunt failure.
Question 142: Extreme dyspnea is being experienced by a 2-year-old with left-sided ventricular heart failure and pulmonary edema. Which of the following would the nurse advise doing to help the youngster breathe easier and feel less anxious and agitated?
- Morphine (Duramorph) (Correct answer)
- Furosemide (Lasix)
- Digoxin (Lanoxin)
- Dobutamine (Dobutrex)
Correct answer: Morphine (Duramorph)
For a 2-year-old experiencing extreme dyspnea, anxiety, and agitation due to left-sided ventricular heart failure and pulmonary edema, morphine is an appropriate intervention. Morphine reduces anxiety and agitation, decreases venous return (preload) by causing venodilation, and can help to alleviate dyspnea by reducing the work of breathing and altering the perception of shortness of breath.
Question 143: A patient complains of sporadic palpitations that come and go and are accompanied by weakness. The heart rate is 125, the PR interval is reduced, and the upstroke is slurred before each enlarged QRS complex, according to an ECG. It is possible to explain this slurred upstroke (Delta wave) by?
- Ventricular repolarization
- Atrial depolarization
- Ventricular pre-excitation (Correct answer)
- Atrial pre-excitation
Correct answer: Ventricular pre-excitation
The ECG findings of a reduced PR interval and a slurred upstroke before an enlarged QRS complex (known as a Delta wave) are classic indicators of ventricular pre-excitation. This condition, often seen in Wolff-Parkinson-White (WPW) syndrome, occurs when an accessory pathway bypasses the AV node, allowing electrical impulses to reach and activate the ventricles prematurely. This early ventricular activation causes the characteristic Delta wave.
Question 144: A 6-year-old on high-frequency oscillatory ventilation (HFOV) for ARDS has improved oxygenation but worsening CO2 retention. Which adjustment corrects this?
- Increase mean airway pressure (MAP)
- Increase amplitude (delta P) (Correct answer)
- Decrease frequency (Hz)
- Increase FiO2
Correct answer: Increase amplitude (delta P)
In HFOV, CO2 elimination is controlled by amplitude (delta P) — increasing amplitude improves the tidal oscillation volume, enhancing CO2 washout.
Question 145: A 9-year-old on a ventilator has peak airway pressures of 42 cm H2O and plateau pressures of 20 cm H2O. What is the most likely cause?
- ET tube displacement into the right mainstem bronchus
- Increased airway resistance from bronchospasm or secretions (Correct answer)
- Decreased lung compliance from ARDS
- Tension pneumothorax developing
Correct answer: Increased airway resistance from bronchospasm or secretions
A high peak pressure with a normal plateau pressure indicates increased resistance in the airways (bronchospasm, mucus), not reduced compliance.
Question 146: A family meeting is scheduled to go over the family's ethical worries about keeping a child on life support who has terminal cancer. The nurse's duties should include:
- Provide the legal standpoint regarding end-of-life decisions for children.
- Articulate the reason for the child's poor prognosis and anticipated life expectancy
- Coordinate the meeting to ensure that everyone has the opportunity to speak
- Assist the parents in articulating their questions and concerns. (Correct answer)
Correct answer: Assist the parents in articulating their questions and concerns.
The nurse's role in an ethical family meeting is to act as a facilitator and advocate for the patient and family. Assisting parents in articulating their questions and concerns ensures their voice is heard and understood by the healthcare team. This empowers the family to participate meaningfully in decision-making regarding their child's end-of-life care.
Question 147: A 2-year-old has continuous focal seizure activity for 20 minutes unresponsive to two doses of benzodiazepines. What is the NEXT pharmacologic step?
- Start a midazolam infusion immediately
- Perform emergent EEG only
- Load IV fosphenytoin or levetiracetam (Correct answer)
- Administer a third dose of lorazepam
Correct answer: Load IV fosphenytoin or levetiracetam
After two failed benzodiazepine doses, status epilepticus is refractory; second-line therapy with IV fosphenytoin or levetiracetam should be given per established treatment algorithms.
Question 148: A male patient, age 16, arrives at the emergency room complaining of nausea, vomiting, and a severe headache. He spent the afternoon cleaning up a paint thinner spill from his side job as a painter. According to him, these symptoms began around an hour after he finished his shift at work. Upon physical examination, he exhibits some degree of confusion, with a heart rate of 115 and a room air oxygen saturation of 95%. Carboxyhemoglobin levels are 23%, according to carbon monoxide oximetry. </br> </br> Which one of the subsequent interventions should the nurse begin applying immediately?
- Administer packed red blood cells
- Initiate the three-part cyanide antidote kit treatment
- Administer protamine sulfate
- Administer 100% oxygen (Correct answer)
Correct answer: Administer 100% oxygen
The patient's symptoms (nausea, vomiting, headache, confusion) and elevated carboxyhemoglobin levels (23%) are classic signs of carbon monoxide (CO) poisoning. CO binds to hemoglobin with much higher affinity than oxygen, forming carboxyhemoglobin and impairing oxygen delivery to tissues. Administering 100% oxygen is the immediate and most effective intervention to displace CO from hemoglobin, accelerate its elimination, and improve tissue oxygenation.
Question 149: A school-aged youngster receives complete parental nutrition (TPN) from nurse Tammy through a peripheral I.V. line. What is the least quantity of glucose deemed safe, won't burn tiny veins, and yet delivers enough TPN?
- 10% (Correct answer)
- 15%
- 13%
- 20%
Correct answer: 10%
For peripheral intravenous (IV) administration of total parenteral nutrition (TPN) in children, the glucose concentration is typically limited to 10%. Higher concentrations are hyperosmolar and can cause phlebitis, irritation, and sclerosis of the small, fragile peripheral veins. If higher glucose concentrations are required to meet nutritional needs, central venous access is necessary to prevent vascular damage.
Question 150: A 4-year-old with diabetic ketoacidosis (DKA) receives IV fluid resuscitation. Four hours later, the child complains of headache and becomes lethargic. The nurse's priority concern is:
- Cerebral edema from rapid fluid shifts (Correct answer)
- Hypoglycemia from overcorrection
- Hypokalemia from insulin therapy
- Hypernatremia from normal saline infusion
Correct answer: Cerebral edema from rapid fluid shifts
Cerebral edema is the most feared complication of pediatric DKA treatment, presenting with altered mental status hours into fluid resuscitation.
Question 151: Which of the following should be done after desmopressin (DDAVP) has been given to a patient with diabetes insipidus?
- Decrease IV fluid rate (Correct answer)
- Increase sodium intake
- Decrease glucose intake
- Maintain current fluid rate
Correct answer: Decrease IV fluid rate
Desmopressin (DDAVP) is an antidiuretic hormone analog that helps the kidneys reabsorb water, significantly reducing urine output in patients with diabetes insipidus. After administering DDAVP, the patient will excrete less fluid, so it is crucial to decrease the IV fluid rate to prevent fluid overload and dilutional hyponatremia. Monitoring fluid balance closely is essential to avoid complications.
Question 152: A juvenile patient who has third-degree burns from an apartment fire and is in septic shock is being admitted by a nurse to the PICU. Which of the following treatments is the nurse planning to administer first?
- Intravenous (IV) vasopressors
- Intravenous (IV) antibiotics
- Intravenous (IV) corticosteroids
- Normal saline (NS) bolus (Correct answer)
Correct answer: Normal saline (NS) bolus
In a patient with septic shock, the immediate priority is to restore circulating blood volume and improve tissue perfusion. Septic shock causes widespread vasodilation and increased capillary permeability, leading to severe hypovolemia. Administering a normal saline (NS) bolus rapidly expands the intravascular volume, which is crucial to stabilize blood pressure and deliver oxygen to vital organs before other treatments can take effect.
Question 153: Which intervention is MOST appropriate as first-line management of hyperphosphatemia in a child with AKI?
- Calcium carbonate with meals as a phosphate binder (Correct answer)
- IV insulin infusion
- Strict sodium restriction
- Aluminum hydroxide antacids
Correct answer: Calcium carbonate with meals as a phosphate binder
Calcium carbonate taken with meals binds dietary phosphate in the GI tract, preventing absorption and lowering serum phosphate without the neurotoxic risk of aluminum-based binders.
Question 154: What are SIDS?
- None of the above
- Special infant death syndromes
- Special infant development
- Sudden infant death syndrome (Correct answer)
Correct answer: Sudden infant death syndrome
SIDS stands for Sudden Infant Death Syndrome. It refers to the sudden, unexpected, and unexplained death of an infant younger than one year of age, typically occurring during sleep. SIDS remains a diagnosis of exclusion after a thorough investigation, including an autopsy, examination of the death scene, and review of the clinical history.
Question 155: Clinical indicators seen in a kid who has been given the diagnosis of failure to thrive include
- Distress when held of left alone
- Excessive crying and delayed language development
- Avoidance of eye contact and delayed motor development (Correct answer)
- No interest in surroundings
Correct answer: Avoidance of eye contact and delayed motor development
Clinical indicators of failure to thrive (FTT) often include developmental delays, such as delayed motor development, and behavioral signs like avoidance of eye contact. These symptoms reflect the impact of chronic malnutrition and neglect on a child's physical and neurological development, as well as their ability to engage in social interaction and explore their environment.
Question 156: A 2-year-old with RSV bronchiolitis has an SpO2 of 89% on room air. Which intervention has the strongest evidence for improving outcomes?
- Systemic corticosteroids to reduce inflammation
- Supplemental oxygen to maintain SpO2 ≥ 90–92% (Correct answer)
- Nebulized albuterol every 4 hours
- Hypertonic saline nebulization with airway suctioning
Correct answer: Supplemental oxygen to maintain SpO2 ≥ 90–92%
Supportive care with supplemental oxygen to maintain adequate saturation is the only consistently evidence-based intervention for RSV bronchiolitis; bronchodilators and steroids are not routinely recommended.
Question 157: In a patient with bronchopulmonary dysplasia (BPD), which ventilatory parameters should be tapered down first?
- Peak inspiratory pressure (PIP) and intermittent mandatory ventilation (IMV)
- Oxygen (FiO2) and intermittent mandatory ventilation (IMV)
- Tidal Volume (VT) and oxygen (FiO2)
- Oxygen (FiO2) and peak inspiratory pressure (PIP) (Correct answer)
Correct answer: Oxygen (FiO2) and peak inspiratory pressure (PIP)
In patients with bronchopulmonary dysplasia (BPD), the primary goal of ventilatory weaning is to reduce lung injury caused by high oxygen concentrations and barotrauma. Therefore, the fraction of inspired oxygen (FiO2) and peak inspiratory pressure (PIP) are typically tapered down first. Reducing FiO2 minimizes oxygen toxicity, while lowering PIP decreases mechanical stress on the fragile developing lungs.
Question 158: After taking prenatal vitamins with iron, a 5-year-old is receiving treatment in the PICU. The nurse assumes all of the following EXCEPT:
- Whole bowel irrigation
- Administration of activated charcoal (Correct answer)
- Gastric lavage
- Administration of ipecac syrup
Correct answer: Administration of activated charcoal
The question asks what the nurse assumes *EXCEPT* when treating iron poisoning. Activated charcoal is generally ineffective in binding iron and is therefore not recommended for iron overdose. Iron is poorly adsorbed by charcoal, making it an unsuitable decontamination method. In contrast, whole bowel irrigation, gastric lavage (if early and large ingestion), and sometimes ipecac syrup (though less common now) are methods that might be considered for decontamination in severe iron poisoning, depending on the clinical situation and timing.
Question 159: A 4-year-old in the PICU has a Glasgow Coma Scale (GCS) score of 8. Which component of the pediatric GCS is CORRECTLY described?
- Motor response: 6 = withdraws from pain
- Eye opening: 4 = opens to verbal command
- Best motor response: 6 = obeys commands (Correct answer)
- Verbal response: 5 = oriented, coos/babbles appropriately for age
Correct answer: Best motor response: 6 = obeys commands
In the GCS motor subscale, a score of 6 indicates the patient obeys commands, which is the highest possible motor response and indicates intact voluntary motor function.
Question 160: Esophageal varices that are bleeding may be treated acutely by:
- Placement of a large NGT to low intermittent suction
- Placement of a central venous line for hyperalimentation (TPN)
- Immediate surgical intervention
- Administration of octreotide (Sandostatin) (Correct answer)
Correct answer: Administration of octreotide (Sandostatin)
Acute bleeding from esophageal varices is often treated with octreotide (Sandostatin). Octreotide is a somatostatin analog that causes splanchnic vasoconstriction, reducing blood flow to the portal system and thereby lowering portal pressure. This reduction in pressure helps to decrease bleeding from the varices, making it a key pharmacological intervention in managing this life-threatening condition.
Question 161: Which clinical sign indicates transtentorial (uncal) herniation in a child with elevated ICP?
- Ipsilateral fixed and dilated pupil with contralateral hemiplegia (Correct answer)
- Bilateral fixed midposition pupils
- Bilateral pinpoint pupils
- Bilateral hyperreflexia
Correct answer: Ipsilateral fixed and dilated pupil with contralateral hemiplegia
Uncal herniation compresses CN III, causing ipsilateral pupil dilation and loss of reactivity, while the herniated brain displaces the contralateral motor tract, producing contralateral weakness.
Question 162: A 12-year-old (40 kg) on CVVH has an effluent rate of 2,000 mL/hr. What is the CRRT dose in mL/kg/hr?
- 100 mL/kg/hr
- 25 mL/kg/hr
- 50 mL/kg/hr (Correct answer)
- 75 mL/kg/hr
Correct answer: 50 mL/kg/hr
CRRT dose = effluent rate ÷ body weight = 2,000 mL/hr ÷ 40 kg = 50 mL/kg/hr, which falls within the recommended pediatric CRRT dosing range.
Question 163: A 5-year-old with known coarctation of the aorta presents with headache and elevated blood pressure in the arms. What is the EXPECTED finding in the legs?
- Equal blood pressure bilaterally
- Absence of pulses only
- Lower blood pressure than the arms (Correct answer)
- Higher blood pressure than the arms
Correct answer: Lower blood pressure than the arms
Coarctation of the aorta causes a blood pressure gradient with higher pressures proximal to the obstruction (arms) and lower pressures distal to it (legs).
Question 164: A child with status epilepticus refractory to benzodiazepines and levetiracetam is started on a continuous midazolam infusion. Which electrolyte abnormality MOST commonly potentiates seizures and must be corrected?
- Hyperkalemia
- Hypermagnesemia
- Hypernatremia
- Hypocalcemia (Correct answer)
Correct answer: Hypocalcemia
Hypocalcemia lowers the seizure threshold by increasing neuronal membrane excitability; correcting low calcium is essential in any child with refractory seizures before escalating anticonvulsant therapy.
Question 165: What is the most typical localized infection in a newborn that occurs preceding or as a result of sepsis?
- Myocarditis
- Meningitis (Correct answer)
- Gastroenteritis
- Hepatitis
Correct answer: Meningitis
Meningitis is the most typical localized infection in a newborn that can precede or result in sepsis. Newborns are particularly vulnerable to central nervous system infections due to their immature immune systems and the potential for pathogens to cross the blood-brain barrier. Untreated or rapidly progressing meningitis can quickly lead to systemic infection and life-threatening sepsis in this vulnerable population.
Question 166: A child with bacterial meningitis develops the sudden onset of a fixed dilated pupil and posturing. The nurse should FIRST:
- Notify the physician immediately and prepare for emergent ICP management (Correct answer)
- Increase the IV fluid rate
- Position the child flat and obtain a STAT CT scan
- Administer a scheduled antibiotic dose
Correct answer: Notify the physician immediately and prepare for emergent ICP management
A fixed dilated pupil with posturing signals cerebral herniation — an immediate life-threatening emergency requiring physician notification and emergent ICP management before any other action.
Question 167: A 10-year-old post-cardiac surgery has a sudden drop in BP, muffled heart sounds, and JVD. The nurse should suspect:
- Pulmonary embolism
- Tension pneumothorax
- Hypovolemic shock
- Cardiac tamponade (Correct answer)
Correct answer: Cardiac tamponade
Beck's triad (hypotension, muffled heart sounds, JVD) is the classic presentation of cardiac tamponade following cardiac surgery.
Question 168: Which of the following symptoms would indicate a newborn with patent ductus arteriosus (PDA)?
- Clubbed fingers and toes
- Narrow pulse pressure
- Bounding peripheral pulses (Correct answer)
- Profound cyanosis
Correct answer: Bounding peripheral pulses
Patent ductus arteriosus (PDA) is a condition where the ductus arteriosus, a fetal blood vessel, fails to close after birth, allowing blood to flow from the aorta to the pulmonary artery. This shunting of blood leads to increased blood flow through the systemic circulation during diastole, resulting in a widened pulse pressure and bounding peripheral pulses. The increased diastolic runoff causes a rapid rise and fall in arterial pressure, creating the characteristic 'bounding' sensation.
Question 169: Which chest X-ray finding is MOST characteristic of total anomalous pulmonary venous return (TAPVR) with obstruction in a neonate?
- Right-sided aortic arch
- Ground-glass opacification with white-out pattern (Correct answer)
- Egg-shaped cardiac silhouette
- 'Snowman' or figure-8 cardiac silhouette
Correct answer: Ground-glass opacification with white-out pattern
Obstructed TAPVR causes severe pulmonary venous hypertension and edema, producing a ground-glass or white-out appearance on CXR due to pulmonary edema.
Question 170: A newborn with transposed great arteries is hospitalized. 46% is the SpO2 value. Nobody makes a murmur. Which drugs should the nurse anticipate being given as a stopgap measure until a balloon septostomy can be performed?
- Digoxin (Lanoxin)
- Indomethacin (Indocin)
- Tolazoline (Priscoline)
- Alprostadil (PGE1) (Correct answer)
Correct answer: Alprostadil (PGE1)
For a newborn with transposed great arteries and severe hypoxemia (SpO2 46%), Alprostadil (PGE1) is the critical medication. PGE1 keeps the ductus arteriosus open, facilitating the mixing of systemic and pulmonary blood flow. This temporary shunt is vital for maintaining adequate systemic oxygenation until a more permanent solution, such as a balloon septostomy or surgical repair, can be carried out.
Question 171: The nurse intends to administer oral antibiotics to a 3-year-old child. Which of the following is the nurse's best course of action?
- "Would you like to take your medicine from a spoon or a cup?" (Correct answer)
- "This will make you feel better once you take it."
- "Do you want to take this pretty medicine?"
- "This is your medicine, and you must take it all now."
Correct answer: "Would you like to take your medicine from a spoon or a cup?"
For a 3-year-old, who is in Erikson's stage of initiative vs. guilt, offering limited choices provides a sense of control and autonomy. Asking 'Would you like to take your medicine from a spoon or a cup?' empowers the child, making them more cooperative and less resistant to taking medication. This approach respects their developing independence without giving them the option to refuse the medication entirely.
Question 172: A child with aortic stenosis has a peak-to-peak gradient of 75 mmHg on cardiac catheterization. This finding indicates:
- Moderate aortic stenosis
- Normal variant in pediatric patients
- Severe aortic stenosis requiring intervention (Correct answer)
- Mild aortic stenosis requiring monitoring only
Correct answer: Severe aortic stenosis requiring intervention
A peak-to-peak gradient ≥70 mmHg across the aortic valve is classified as severe aortic stenosis and typically warrants balloon valvuloplasty or surgical intervention.
Question 173: Which of the following does positive end-expiratory pressure (PEEP) aim to accomplish?
- Increase cardiac output
- Increase functional residual capacity (Correct answer)
- Increase venous return to the heart
- Decrease functional residual capacity
Correct answer: Increase functional residual capacity
Positive end-expiratory pressure (PEEP) is a ventilatory maneuver that maintains a positive pressure in the airways at the end of exhalation. Its primary goal is to prevent alveolar collapse (atelectasis) and recruit collapsed alveoli, thereby increasing the functional residual capacity (FRC). By keeping alveoli open, PEEP improves oxygenation, reduces the work of breathing, and optimizes gas exchange.
Question 174: What is the correct maintenance fluid requirement for a 20 kg child using the Holliday-Segar method?
- 1,200 mL/day
- 1,500 mL/day (Correct answer)
- 1,600 mL/day
- 1,400 mL/day
Correct answer: 1,500 mL/day
Using the 100-50-20 rule: 100 mL/kg × 10 kg = 1,000 mL + 50 mL/kg × 10 kg = 500 mL, totaling 1,500 mL/day.
Question 175: Family members of a recently deceased patient are sobbing and wailing loudly. The outbursts are making the staff angry. The ideal response from the nurse is to acknowledge the loudness and:
- Tell the other staff they are being insensitive to the family's expression of grief
- Ask a security officer to remove the family from the unit
- Tell the family they must quiet down, or they will have to leave the unit
- Guide the family to a nearby room where they can express their emotions (Correct answer)
Correct answer: Guide the family to a nearby room where they can express their emotions
Grieving families need a safe and private space to express their emotions without feeling judged or constrained. Guiding the family to a nearby room acknowledges their need for emotional release while also respecting the environment for other patients and staff. This demonstrates empathy and provides appropriate support during a difficult time.
Question 176: A 4-year-old post-Fontan procedure has rising lactate and falling mixed venous oxygen saturation. The MOST likely cause is:
- Metabolic alkalosis
- Low cardiac output syndrome (Correct answer)
- Arrhythmia-induced heart block
- Pulmonary hypertension crisis
Correct answer: Low cardiac output syndrome
Rising lactate and falling SvO2 are hallmarks of low cardiac output syndrome, indicating tissues are extracting more oxygen due to inadequate delivery.
Question 177: A 3-month-old presents with poor feeding, weak cry, constipation, and decreased muscle tone. The nurse suspects infant botulism. What is the most appropriate initial intervention?
- Administer BabyBIG (botulism immune globulin) and prepare for respiratory support (Correct answer)
- Initiate activated charcoal to bind toxin
- Start broad-spectrum IV antibiotics
- Administer botulism antitoxin (HBAT) immediately
Correct answer: Administer BabyBIG (botulism immune globulin) and prepare for respiratory support
BabyBIG (heptavalent botulism immune globulin) is the specific treatment for infant botulism, and respiratory support should be anticipated due to progressive weakness.
Question 178: A premature neonate has abdominal distension, bloody stools, and pneumatosis intestinalis on X-ray. These findings are consistent with:
- Malrotation with mid-gut volvulus
- Meconium ileus from cystic fibrosis
- Hirschsprung disease with enterocolitis
- Necrotizing enterocolitis (NEC) (Correct answer)
Correct answer: Necrotizing enterocolitis (NEC)
Pneumatosis intestinalis (air in the bowel wall) is pathognomonic for NEC, a life-threatening intestinal emergency in premature neonates.
Question 179: Which tissue is not impacted by leukemia?
- Bone marrow
- Lymph
- Liver
- Kidney (Correct answer)
Correct answer: Kidney
Leukemia is a cancer of the blood-forming tissues, primarily originating in the bone marrow. While it can spread and affect organs rich in lymphatic tissue, such as the liver, spleen, and lymph nodes, the kidney is not a primary site of leukemia cell proliferation. Although leukemia can indirectly cause kidney damage through complications like tumor lysis syndrome, the kidney itself is not directly impacted as a tissue where leukemia typically originates or extensively infiltrates.
Question 180: A 5-year-old is noted to have subtle lip smacking and eye blinking lasting 90 seconds followed by confusion. This event is BEST classified as:
- Generalized tonic-clonic seizure
- Myoclonic seizure
- Absence seizure
- Focal impaired awareness seizure (complex partial seizure) (Correct answer)
Correct answer: Focal impaired awareness seizure (complex partial seizure)
Repetitive automatisms (lip smacking, eye blinking) with impaired awareness followed by post-ictal confusion characterize focal impaired awareness seizures originating in the temporal lobe.
Question 181: A 3-year-old presents with drooling, high fever, tripod positioning, and muffled voice. Which action should the nurse AVOID?
- Performing a throat examination with a tongue depressor (Correct answer)
- Administering humidified oxygen by blow-by
- Keeping the child calm and upright
- Preparing for emergency airway management
Correct answer: Performing a throat examination with a tongue depressor
In suspected epiglottitis, throat examination or any distressing procedure can precipitate complete airway obstruction; the airway must be secured in a controlled OR setting first.
Question 182: A 5-year-old is admitted after a near-drowning event and is initially alert. Two hours later, the child's respiratory status deteriorates and the chest X-ray shows bilateral infiltrates. This progression is most consistent with:
- Secondary drowning / neurogenic pulmonary edema (Correct answer)
- Flash pulmonary edema from hypothermia
- Aspiration pneumonia from inhaled water
- Delayed tension pneumothorax
Correct answer: Secondary drowning / neurogenic pulmonary edema
Secondary drowning (also called delayed drowning) occurs hours after the event as inhaled water causes surfactant washout and ARDS-like pulmonary edema.
Question 183: A neonate born at 28 weeks gestation is on high-frequency oscillatory ventilation (HFOV). Which parameter is primarily adjusted to control oxygenation on HFOV?
- Mean airway pressure (MAP) (Correct answer)
- Frequency (Hz)
- Inspiratory time
- Amplitude (ΔP)
Correct answer: Mean airway pressure (MAP)
On HFOV, mean airway pressure (MAP) controls lung volume and oxygenation, while amplitude (ΔP) controls CO2 elimination.
Question 184: A 4-year-old with nephrotic syndrome develops sudden severe abdominal pain, fever, and peritoneal signs. The most likely diagnosis is:
- Mesenteric adenitis from viral infection
- Intussusception from bowel edema
- Splenic sequestration crisis
- Spontaneous bacterial peritonitis (Correct answer)
Correct answer: Spontaneous bacterial peritonitis
Children with nephrotic syndrome are highly susceptible to spontaneous bacterial peritonitis (typically Streptococcus pneumoniae) due to loss of immunoglobulins in the urine.
Question 185: Which medication is the antidote for acetaminophen (paracetamol) toxicity in a pediatric patient?
- Physostigmine
- Naloxone
- N-acetylcysteine (NAC) (Correct answer)
- Flumazenil
Correct answer: N-acetylcysteine (NAC)
N-acetylcysteine replenishes hepatic glutathione, binding the toxic NAPQI metabolite to prevent liver injury, and is most effective when given within 8–10 hours of acetaminophen ingestion.
Question 186: Which of the following conditions are more likely in patients with cardiac abnormalities linked to increased pulmonary blood flow?
- Hypoxemia
- Heart Failure (Correct answer)
- Air Emboli
- Syncope
Correct answer: Heart Failure
Cardiac abnormalities linked to increased pulmonary blood flow, such as large ventricular septal defects (VSDs) or patent ductus arteriosus (PDA), cause a left-to-right shunt. This leads to an excessive volume of blood flowing into the pulmonary circulation, increasing the workload on the heart and lungs. Over time, this sustained overload can lead to pulmonary hypertension and ultimately result in congestive heart failure.
Question 187: Which hemodynamic pattern is most consistent with septic shock in a 5-year-old in the early (warm) phase?
- Low CO, low SVR, mottled skin
- Low CO, high SVR, cool extremities
- High CO, low SVR, warm extremities (Correct answer)
- High CO, high SVR, bounding pulses
Correct answer: High CO, low SVR, warm extremities
Early septic shock (warm shock) is characterized by vasodilation (low SVR) and compensatory high cardiac output with warm, flushed extremities.
Question 188: A 10-year-old develops complete heart block after surgical repair of an AV canal defect. What is the immediate intervention?
- Start IV amiodarone infusion
- Perform synchronized cardioversion
- Initiate temporary epicardial pacing (Correct answer)
- Administer atropine IV
Correct answer: Initiate temporary epicardial pacing
Epicardial pacing wires are routinely placed during open-heart surgery; activating temporary epicardial pacing is the immediate treatment for postoperative complete heart block.
Question 189: Which of the following findings should a nurse disclose right away when examining a 3-week-old baby:
- Inspiratory grunting (Correct answer)
- Irregular breathing pattern
- Abdominal respiration
- Increased cardiac rate when crying
Correct answer: Inspiratory grunting
Inspiratory grunting in a 3-week-old baby is a significant sign of respiratory distress and should be reported immediately. Grunting is the sound of air being exhaled against a partially closed glottis, which helps to increase end-expiratory pressure and prevent alveolar collapse. This compensatory mechanism indicates increased work of breathing and potential underlying respiratory pathology requiring urgent assessment.
Question 190: Which of the following variables will cause the oxyhemoglobin dissociation curve to shift to the right and have a negative effect?
- Respiratory alkalosis
- Hyperthermia (Correct answer)
- Metabolic alkalosis
- Hypothermia
Correct answer: Hyperthermia
The oxyhemoglobin dissociation curve shifts to the right when there is a decrease in hemoglobin's affinity for oxygen, meaning oxygen is more readily released to the tissues. Factors that cause a right shift include increased temperature (hyperthermia), increased PCO2, increased 2,3-DPG, and decreased pH (acidosis). Hyperthermia increases metabolic demand, requiring more oxygen delivery to tissues.
Question 191: Which of the following observations supports the assertion that a 6-month-old has brain death?
- Low-voltage amplitude observed on electroencephalogram (EEG)
- Eyes deviate toward the right when ice water is injected into the ears.
- Radionuclide scan shows cerebral arterial blood flow into the brain stem.
- Absence of spontaneous breathing when PaCO2 goes above 60 mmHg (Correct answer)
Correct answer: Absence of spontaneous breathing when PaCO2 goes above 60 mmHg
The absence of spontaneous breathing when the PaCO2 rises above 60 mmHg is a critical component of the apnea test, which is used to determine brain death. This finding indicates a complete and irreversible loss of brainstem function, as the brainstem is responsible for initiating respiration in response to elevated carbon dioxide levels. It is a key criterion for confirming brain death.
Question 192: A bowel management program is established for a child with myelomeningocele. The nurse will acknowledge that additional knowledge is necessary when the mother states, My child:
- will require more activity to increase bowel movements.
- will be unable to control his bowel movements.
- tends to be more prone to diarrhea. (Correct answer)
- needs to have a bowel movement every day.
Correct answer: tends to be more prone to diarrhea.
Children with myelomeningocele often have neurogenic bowel, which typically leads to chronic constipation and fecal incontinence due to impaired nerve function. They are generally not prone to diarrhea, unless there is an underlying infection or specific dietary issue. Therefore, the mother's statement about her child tending to be more prone to diarrhea indicates a need for further education on the typical bowel patterns associated with myelomeningocele.
Question 193: A nurse is gathering materials to start intravenous (IV) fluid resuscitation and a blood transfusion using packed red blood cells (PRBCs) as she gets ready to admit a child with a new diagnosis of sickle cell disease (SCD). Why is it necessary to use these interventions?
- To reduce pain caused by sickling
- To reduce kidney damage and correct acidosis
- To treat dehydration and anemia (Correct answer)
- To reverse hypovolemic shock
Correct answer: To treat dehydration and anemia
Children with sickle cell disease (SCD) are prone to dehydration, which can trigger painful vaso-occlusive crises, and chronic anemia due to the premature destruction of sickled red blood cells. Intravenous (IV) fluid resuscitation is crucial to correct dehydration and improve blood flow. Blood transfusions with packed red blood cells (PRBCs) are administered to treat severe anemia, increase oxygen-carrying capacity, and dilute the concentration of sickled cells, thereby reducing the risk of further complications.
Question 194: What causes a loud, high-pitched sound during breathing?
- Nostril contraction
- Nasal constraints
- Lymph
- Stridor (Correct answer)
Correct answer: Stridor
Stridor is a harsh, high-pitched, musical sound produced during breathing, typically heard on inspiration. It is caused by turbulent airflow through a partially obstructed upper airway, such as the larynx or trachea. Stridor is a significant clinical sign indicating potential airway compromise and requires immediate assessment and intervention.
Question 195: Which of the four primary types of cerebral aneurysms is most frequently found in the brain's basilar arteries?
- Mycotic aneurysm
- Fusiform (giant) aneurysm (Correct answer)
- Saccular (berry) aneurysm
- Traumatic aneurysm
Correct answer: Fusiform (giant) aneurysm
Fusiform aneurysms are characterized by a circumferential dilation of a blood vessel, often appearing as a spindle-shaped bulge, rather than a sac-like protrusion. These types of aneurysms are more commonly found in the basilar arteries and other large vessels at the base of the brain. Their 'giant' designation refers to their size, typically greater than 2.5 cm, and they are often associated with atherosclerosis or dissection.
Question 196: Which intervention is HIGHEST priority in the first hour of management of severe traumatic brain injury in a child?
- Initiate hypertonic saline prophylactically
- Obtain MRI of the brain
- Prevent secondary injury by maintaining adequate CPP and avoiding hypoxia/hypotension (Correct answer)
- Administer high-dose steroids
Correct answer: Prevent secondary injury by maintaining adequate CPP and avoiding hypoxia/hypotension
After TBI, secondary brain injury from hypoxia, hypotension, hyperthermia, and elevated ICP causes most preventable deaths; maintaining CPP and oxygenation is the top priority.
Question 197: Digoxin (Lanoxin) is prescribed to a young patient for heart failure. The nurse understands that poisoning is often detected at what value?
- 5 ng/mL
- 3.5 ng/mL
- 4 ng/mL
- 2 ng/mL (Correct answer)
Correct answer: 2 ng/mL
Digoxin has a narrow therapeutic index, meaning the range between effective and toxic doses is small. While the therapeutic range for digoxin is typically 0.5-2.0 ng/mL, levels at or above 2.0 ng/mL are generally considered indicative of toxicity, especially in pediatric patients who are more sensitive. Monitoring digoxin levels is crucial to prevent adverse effects such as arrhythmias, nausea, and vomiting.
Question 198: What is the PRIMARY concern when using succinylcholine for rapid sequence intubation in a child with a crush injury?
- Life-threatening hyperkalemia (Correct answer)
- Bradycardia
- Malignant hyperthermia
- Prolonged neuromuscular blockade
Correct answer: Life-threatening hyperkalemia
Crush injury causes massive upregulation of extrajunctional acetylcholine receptors; succinylcholine depolarization releases dangerous amounts of potassium into the circulation, risking fatal arrhythmias.
Question 199: A 3-year-old after cardiac surgery has a heart rate of 220 bpm with a narrow QRS and sudden onset. What is the FIRST-LINE treatment?
- Adenosine IV rapid push
- Synchronized cardioversion
- Vagal maneuvers (Correct answer)
- Amiodarone IV infusion
Correct answer: Vagal maneuvers
Vagal maneuvers (e.g., ice to face in infants, Valsalva in older children) are the first-line intervention for stable SVT and should be attempted before pharmacologic therapy.
Question 200: A 5-year-old is admitted for hypertensive urgency. The drug of choice for acute, controlled reduction of blood pressure in a PICU setting is:
- IV furosemide bolus dosing
- Oral nifedipine (sublingual administration)
- IM hydralazine every 6 hours
- Continuous IV nicardipine or labetalol infusion (Correct answer)
Correct answer: Continuous IV nicardipine or labetalol infusion
Continuous IV nicardipine or labetalol allows precise, titratable blood pressure control, preventing the dangerous overcorrection associated with bolus agents.
Question 201: Which electrolyte imbalance is most likely in a child with prolonged nasogastric suctioning?
- Hypokalemia and metabolic alkalosis (Correct answer)
- Hyponatremia and metabolic alkalosis
- Hypernatremia and metabolic acidosis
- Hyperkalemia and metabolic acidosis
Correct answer: Hypokalemia and metabolic alkalosis
Gastric fluid loss via NG suctioning depletes hydrochloric acid, potassium, and sodium, resulting in hypokalemic, hypochloremic metabolic alkalosis.
Question 202: A 10-year-old with cystic fibrosis is admitted with a pulmonary exacerbation. Which combination is standard initial therapy?
- Bronchodilators and bed rest
- Inhaled tobramycin alone
- IV antibiotics targeting Pseudomonas plus airway clearance therapy (Correct answer)
- Systemic corticosteroids alone
Correct answer: IV antibiotics targeting Pseudomonas plus airway clearance therapy
CF pulmonary exacerbations require IV antibiotics with anti-pseudomonal coverage (e.g., tobramycin + piperacillin-tazobactam) combined with aggressive airway clearance to improve outcomes.
Question 203: Clinical indicators seen in a kid who has been given the diagnosis of failure to thrive include what?
- Avoidance of eye contact and delayed motor development (Correct answer)
- Distress when held of left alone
- Excessive crying and delayed language development
- No interest in surroundings
Correct answer: Avoidance of eye contact and delayed motor development
Mr. Jackson was already admitted as an inpatient, and his personal doctor visits him the *day after* admission for a checkup. This scenario describes subsequent hospital care, which refers to services provided by a physician to a patient who is already admitted to the hospital. Initial hospital care codes (99221-99223) are for the first day of admission, while observation care and outpatient services are for different settings.
Question 204: A child with a large ventricular septal defect is at greatest risk for developing which complication over time if left unrepaired?
- Complete heart block
- Tricuspid atresia
- Coarctation of the aorta
- Eisenmenger syndrome (Correct answer)
Correct answer: Eisenmenger syndrome
Chronic left-to-right shunting from a large VSD causes pulmonary hypertension; when pulmonary pressure exceeds systemic, Eisenmenger syndrome (reversal of shunt) develops.
Question 205: A child in the PICU receives a continuous midazolam infusion for 5 days. When the infusion is weaned, the child develops agitation, tremors, and diaphoresis. This presentation is MOST consistent with:
- Benzodiazepine withdrawal syndrome (Correct answer)
- Thyroid storm
- Opioid toxicity
- Sepsis-associated delirium
Correct answer: Benzodiazepine withdrawal syndrome
Prolonged benzodiazepine infusions cause physical dependence; abrupt weaning produces a withdrawal syndrome with CNS excitability, autonomic instability (diaphoresis, tachycardia), and tremors.
Question 206: What is the correct formula for estimated endotracheal tube size (uncuffed) in a child over 2 years of age?
- (Age in years + 16) / 4
- (Age in years / 4) + 3
- (Age in years / 4) + 4 (Correct answer)
- Age in years / 3 + 3.5
Correct answer: (Age in years / 4) + 4
The standard formula for uncuffed ETT size in children over 2 years is (age in years ÷ 4) + 4, though cuffed tubes one size smaller are increasingly preferred in PICUs.
Question 207: Which corticosteroid dose is recommended for physiologic stress dosing (adrenal insufficiency coverage) in a critically ill child under 10 kg?
- Methylprednisolone 2 mg/kg/day
- Dexamethasone 0.6 mg/kg once
- Hydrocortisone 1 mg/kg/day
- Hydrocortisone 50 mg/m² /day (stress dose: 3–5× maintenance) (Correct answer)
Correct answer: Hydrocortisone 50 mg/m² /day (stress dose: 3–5× maintenance)
Physiologic stress dosing of hydrocortisone is 3–5 times the maintenance dose, calculated at 50–100 mg/m²/day, to cover the adrenal response that the pituitary-adrenal axis may fail to mount during critical illness.
Question 208: What desired outcome is achieved when amrinone lactate (Inocor) is administered?
- Decreased myocardial contractility
- Catecholamine antagonism
- Vasodilation (Correct answer)
- Phospholipid inhibition
Correct answer: Vasodilation
Amrinone lactate (Inocor) is a phosphodiesterase inhibitor that increases intracellular cyclic AMP (cAMP) in both cardiac and vascular smooth muscle cells. In the heart, this leads to increased contractility (positive inotropy). In vascular smooth muscle, increased cAMP causes relaxation, resulting in systemic and pulmonary vasodilation, which reduces afterload. This dual action improves cardiac output by both strengthening contractions and reducing the resistance the heart pumps against.
Question 209: A 7-year-old with nephrotic syndrome has periorbital edema and a serum albumin of 1.5 g/dL. What is the PRIMARY pathophysiology of edema in nephrotic syndrome?
- Sodium retention from SIADH
- Lymphatic obstruction
- Decreased plasma oncotic pressure (Correct answer)
- Increased hydrostatic pressure
Correct answer: Decreased plasma oncotic pressure
Massive proteinuria leads to hypoalbuminemia, which reduces plasma oncotic pressure and allows fluid to leak into the interstitial space, causing edema.
Question 210: A child with hemolytic uremic syndrome (HUS) develops seizures and altered mental status. The pathophysiology of neurological involvement in HUS is best explained by:
- Hypoglycemia secondary to renal failure
- Hypercalcemia from vitamin D dysregulation
- Benign intracranial hypertension from fluid overload
- Thrombotic microangiopathy affecting cerebral vessels (Correct answer)
Correct answer: Thrombotic microangiopathy affecting cerebral vessels
Shiga toxin in HUS triggers thrombotic microangiopathy that can affect cerebral blood vessels, causing endothelial injury, microthrombi, and neurological complications including seizures and encephalopathy.
Pediatric CCRN Exam
This exam certifies registered nurses who provide direct care to critically ill pediatric patients, demonstrating advanced knowledge in clinical judgment and professional practice.
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