Medical Laboratory Technician Exam Medical Laboratory Technician Hematology and Coagulation Questions and Answers 2

Question 1

A patient's blood smear shows hypersegmented neutrophils with macro-ovalocytes. Which vitamin deficiency is most likely responsible for these findings?

Accepted Answer

Vitamin B12 or folate deficiency

Answer

Hypersegmented neutrophils and macro-ovalocytes are hallmark findings of megaloblastic anemia caused by vitamin B12 or folate deficiency.

Question 2

Which coagulation pathway is assessed by the activated partial thromboplastin time (aPTT)?

Accepted Answer

Intrinsic and common pathways

Answer

The aPTT evaluates factors in the intrinsic pathway (XII, XI, IX, VIII) and the common pathway (X, V, II, fibrinogen).

Question 3

What is the expected reticulocyte count pattern in a patient with aplastic anemia?

Accepted Answer

Decreased reticulocyte count

Answer

Aplastic anemia involves bone marrow failure, resulting in decreased production of all cell lines including reticulocytes.

Question 4

A prolonged thrombin time (TT) that corrects with a mixing study most likely indicates which condition?

Accepted Answer

Factor deficiency

Answer

Correction with a mixing study indicates a factor deficiency rather than an inhibitor, as the normal plasma supplies the missing factor.

Question 5

Which hemoglobin electrophoresis pattern is characteristic of sickle cell trait (HbAS)?

Accepted Answer

HbA greater than HbS with normal HbA2

Answer

In sickle cell trait, HbA predominates over HbS (typically 55-60% HbA and 35-40% HbS) with normal HbA2 levels.

Medical Laboratory Technician Exam Practice Test

Medical Laboratory Technician Exam Practice Test

Medical Laboratory Technician Exam Medical Laboratory Technician Hematology and Coagulation Questions and Answers 2