CSR CSR Pharmacology & Drug-Nutrient Interactions in Renal Disease

Question 1

Which phosphate binder is calcium-based and commonly used to manage hyperphosphatemia in CKD patients?

Accepted Answer

Calcium acetate

Answer

Calcium acetate is a calcium-based phosphate binder used to control hyperphosphatemia in CKD patients.

Question 2

Which antihypertensive drug class can significantly increase serum potassium by reducing aldosterone secretion in CKD patients?

Accepted Answer

ACE inhibitors

Answer

ACE inhibitors reduce aldosterone secretion, leading to potassium retention and increased hyperkalemia risk in CKD.

Question 3

Sevelamer is preferred over calcium-based phosphate binders in CKD patients who have which condition?

Accepted Answer

Hypercalcemia or vascular calcification

Answer

Sevelamer is preferred when calcium-based binders may worsen hypercalcemia or contribute to vascular calcification.

Question 4

Which vitamin supplement requires active-form supplementation in CKD due to impaired renal 1-alpha hydroxylation?

Accepted Answer

Calcitriol (active vitamin D)

Answer

CKD impairs renal 1-alpha hydroxylation of vitamin D, requiring supplementation with its active form, calcitriol.

Question 5

Loop diuretics in CKD patients may increase risk of which electrolyte deficiency due to increased urinary losses?

Accepted Answer

Hypomagnesemia

Answer

Loop diuretics increase urinary magnesium excretion, predisposing CKD patients to hypomagnesemia.

(CSR) Board Certified Specialist in Renal Nutrition Practice Test