CSR CSR Pharmacology & Drug-Nutrient Interactions in Renal Disease

Question 1

Which phosphate binder is calcium-based and commonly used to manage hyperphosphatemia in CKD patients?

Accepted Answer

Calcium acetate

Answer

Sevelamer carbonate

Answer

Lanthanum carbonate

Answer

Sucroferric oxyhydroxide

Question 2

Which antihypertensive drug class can significantly increase serum potassium by reducing aldosterone secretion in CKD patients?

Accepted Answer

ACE inhibitors

Answer

Calcium channel blockers

Answer

Loop diuretics

Answer

Thiazide diuretics

Question 3

Sevelamer is preferred over calcium-based phosphate binders in CKD patients who have which condition?

Accepted Answer

Hypercalcemia or vascular calcification

Answer

Hypocalcemia

Answer

Hypomagnesemia

Answer

Iron deficiency anemia

Question 4

Which vitamin supplement requires active-form supplementation in CKD due to impaired renal 1-alpha hydroxylation?

Accepted Answer

Calcitriol (active vitamin D)

Answer

Vitamin C

Answer

Vitamin B12

Answer

Vitamin E

Question 5

Loop diuretics in CKD patients may increase risk of which electrolyte deficiency due to increased urinary losses?

Accepted Answer

Hypomagnesemia

Answer

Hyperkalemia

Answer

Hyperphosphatemia

Answer

Hypercalcemia

Question 6

Erythropoiesis-stimulating agents (ESAs) used for anemia in CKD require adequate stores of which nutrient for efficacy?

Accepted Answer

Iron

Answer

Calcitriol

Answer

Zinc

Answer

Folate