CCTC CCTC - Certified Clinical Transplant Coordinator Infection Prevention and Management Questions and Answers 2

Question 1

When BK viremia is detected on surveillance in a kidney transplant recipient, the standard first intervention is:

Accepted Answer

Reducing immunosuppression, typically by decreasing mycophenolate dose

Answer

Reduction of immunosuppression — most commonly decreasing or stopping mycophenolate — is the primary treatment for BK viremia to allow the immune system to control viral replication.

Question 2

Which live vaccine is CONTRAINDICATED in immunocompromised solid organ transplant recipients?

Accepted Answer

MMR (measles, mumps, rubella)

Answer

MMR is a live attenuated vaccine and is absolutely contraindicated post-transplant due to the risk of vaccine-strain infection in immunocompromised hosts.

Question 3

Annual inactivated influenza vaccination is recommended for transplant recipients primarily because:

Accepted Answer

Influenza infection can trigger acute rejection and cause severe disease in immunocompromised hosts

Answer

Influenza can cause severe illness, pneumonia, and may trigger immune activation leading to acute rejection in transplant recipients, making annual vaccination critical.

Question 4

A liver transplant recipient who received a TB-positive donor organ (via IGRA) requires post-transplant treatment. The preferred regimen for latent TB infection (LTBI) treatment in this setting is:

Accepted Answer

Isoniazid (INH) for 9 months with vitamin B6 supplementation

Answer

Isoniazid 9-month therapy with pyridoxine (B6) to prevent peripheral neuropathy is the standard LTBI treatment in transplant recipients, though timing and choice may vary by center.

Question 5

The MOST important preventive measure a transplant coordinator can reinforce to reduce surgical site infection (SSI) after transplant surgery is:

Accepted Answer

Strict hand hygiene and proper wound care as instructed by the surgical team

Answer

Hand hygiene and proper wound assessment/care are the most evidence-based interventions to prevent SSI and should be reinforced at every post-operative visit.

CCTC - Certified Clinical Transplant Coordinator Practice Test

CCTC - Certified Clinical Transplant Coordinator Practice Test

CCTC CCTC - Certified Clinical Transplant Coordinator Infection Prevention and Management Questions and Answers 2