ONCC Chemotherapy Administration and Safety

Question 1

When administering a vesicant chemotherapy agent via peripheral IV, how often should the nurse assess the site for signs of extravasation?

Accepted Answer

Every 30 minutes during infusion

Answer

Vesicants require assessment every 30 minutes during infusion because extravasation can cause severe tissue necrosis and must be caught immediately.

Question 2

A nurse is preparing to administer doxorubicin. Which piece of personal protective equipment (PPE) is MOST essential according to NIOSH hazardous drug handling guidelines?

Accepted Answer

Double chemotherapy-rated gloves and a closed-front gown

Answer

NIOSH guidelines for hazardous drug handling require double chemotherapy-rated gloves and a closed-front impermeable gown to minimize skin absorption and contamination.

Question 3

Which action is the FIRST priority when a chemotherapy extravasation is suspected?

Accepted Answer

Stop the infusion immediately and disconnect the IV tubing

Answer

Stopping the infusion immediately and disconnecting the IV tubing without removing the needle limits further tissue damage from the vesicant agent.

Question 4

A patient is ordered paclitaxel. Before administration, the nurse should premedicate with which combination to prevent hypersensitivity reactions?

Accepted Answer

Dexamethasone, diphenhydramine, and an H2 blocker

Answer

Paclitaxel requires premedication with a corticosteroid (dexamethasone), an antihistamine (diphenhydramine), and an H2 blocker to prevent the hypersensitivity reactions caused by the Cremophor EL vehicle.

Question 5

Which of the following is the correct approach for handling a chemotherapy spill on the floor?

Accepted Answer

Don PPE, use a spill kit, clean from the outside in, and dispose in a yellow hazardous waste container

Answer

Chemotherapy spills require PPE, a designated spill kit, cleaning from the outside inward to contain the spill, and disposal in an approved hazardous waste container.

ONCC - Oncology Nursing Certification Corporation Practice Test

ONCC - Oncology Nursing Certification Corporation Practice Test

ONCC Chemotherapy Administration and Safety