Free ONCC Advanced Oncology Certified Nurse Practitioner Questions and Answers

Question 1

Which of the following cancers is the leading killer worldwide?

Accepted Answer

Lung

Answer

Stomach

Answer

Colorectal

Answer

Liver

Question 2

Which of the following cancer types has decreased the most in incidence during the previous decade?

Accepted Answer

Prostate

Answer

Lung

Answer

Female breast

Answer

Melanoma

Question 3

Which of the following races has the highest mortality due to cancer?

Accepted Answer

African American

Answer

Hispanic

Answer

Caucasian

Answer

Asian/Pacific Islanders

Question 4

According to a current theory of carcinogenesis, which of the following are not required to transform normal cells into malignant ones?

Accepted Answer

Apoptosis

Answer

A carcinogenic initiating agent

Answer

A promoter

Answer

Permanent DNA mutation

Question 5

The tumor suppressor gene p53:

Accepted Answer

when mutated, is associated with common human tumors, such as bladder, breast, colon, or lung.

Answer

is the least common mutated tumor suppressor gene found in human cancers.

Answer

when mutated, promotes apoptosis.

Answer

when mutated, carries out dna repair.

Question 6

Which pattern of cellular growth is characteristic of cancer cells?

Accepted Answer

Anaplasia

Answer

Hyperplasia

Answer

Metaplasia

Answer

Dysplasia

Question 7

Which of the following would confer the worst prognosis for female breast cancer?

Accepted Answer

Inflammatory histology

Answer

Lobular carcinoma in situ

Answer

1.0 cm tumor in left breast

Answer

Estrogen-positive receptors

Question 8

A 60-year-old man with a 40-pack-year history of cigarette smoking presents with a chronic cough but little sputum, a 10 lb weight loss, and generalized fatigue. The chest x-ray shows a possible perihilar mass but clear peripheral lung fields. Which of the following procedures would most likely provide a definite diagnosis of lung cancer?

Accepted Answer

Bronchoscopy with brush or needle biopsy

Answer

Sputum examination with cytology

Answer

CT exam of the chest

Answer

Transthoracic fine-needle biopsy

Question 9

According to the TNM (Tumor, Node, Metastases) staging system in widespread use, which of the following would be expected to have the highest stage and most likely the worst prognosis in a case of gastric cancer?

Accepted Answer

TINOM1

Answer

TINOMO

Answer

T2N2MO

Answer

TIN2MO

Question 10

Cancer of the uterine cervix:

Accepted Answer

is often associated with certain strains of HPV.

Answer

is usually an adenocarcinoma.

Answer

can be diagnosed by an abnormal Pap smear alone.

Answer

has increased in incidence in the United States over the past 50 years.