OGT Interpreting OGTT Results and Glucose Tolerance Classifications 3

Question 1

According to WHO criteria, what 2-hour OGTT plasma glucose value is diagnostic for diabetes mellitus?

Accepted Answer

≥200 mg/dL

Answer

Both the WHO and ADA use a 2-hour plasma glucose ≥200 mg/dL (11.1 mmol/L) after a 75g oral glucose load as the diagnostic threshold for diabetes mellitus.

Question 2

The IADPSG recommends diagnosing gestational diabetes when fasting glucose exceeds which value?

Accepted Answer

92 mg/dL

Answer

IADPSG criteria diagnose gestational diabetes when fasting plasma glucose is ≥92 mg/dL, lower than the traditional Carpenter-Coustan threshold of 95 mg/dL.

Question 3

A patient's 1-hour value during a 3-hour GDM OGTT is 195 mg/dL (Carpenter-Coustan threshold: 180 mg/dL). What does this single abnormal value indicate?

Accepted Answer

The finding is borderline; at least one more abnormal value is needed for diagnosis

Answer

In the Carpenter-Coustan system, one abnormal value is considered borderline; at least two of the four values must meet or exceed thresholds to diagnose gestational diabetes.

Question 4

When comparing ADA and WHO interpretation criteria for the standard 75g OGTT, which statement is correct?

Accepted Answer

Both use ≥200 mg/dL as the 2-hour diagnostic threshold for diabetes

Answer

Both the ADA and WHO use ≥200 mg/dL as the 2-hour plasma glucose threshold for diabetes diagnosis using the 75g OGTT.

Question 5

Isolated post-challenge hyperglycemia (elevated 2-hour OGTT with normal fasting glucose) is clinically significant because:

Accepted Answer

It independently predicts cardiovascular risk and progression to diabetes

Answer

Isolated post-challenge hyperglycemia independently predicts increased cardiovascular disease risk and future progression to type 2 diabetes, even when fasting glucose is normal.

OGT - Oral Glucose Tolerance Practice Test

OGT - Oral Glucose Tolerance Practice Test

OGT Interpreting OGTT Results and Glucose Tolerance Classifications 3