OGT Medications and Factors Affecting OGTT Results

Question 1

Which drug class is well-known for causing hyperglycemia that can produce a false-positive OGTT?

Accepted Answer

Corticosteroids

Answer

ACE inhibitors

Answer

Beta-blockers

Answer

Loop diuretics

Question 2

Which antihypertensive class can mask hypoglycemic symptoms and potentially confound OGTT interpretation?

Accepted Answer

Beta-blockers

Answer

ACE inhibitors

Answer

Calcium channel blockers

Answer

ARBs

Question 3

Thiazide diuretics affect OGTT results by:

Accepted Answer

Raising blood glucose by impairing insulin secretion and increasing insulin resistance

Answer

Lowering blood glucose through increased renal excretion

Answer

Having no effect on glucose metabolism

Answer

Stimulating GLP-1 release

Question 4

Niacin (nicotinic acid) at pharmacological doses used for dyslipidemia can affect OGTT by:

Accepted Answer

Raising plasma glucose through insulin resistance

Answer

Improving insulin sensitivity

Answer

Lowering fasting glucose

Answer

Having no metabolic effect

Question 5

Which immunosuppressant used in organ transplant patients commonly causes post-transplant diabetes and abnormal OGTT?

Accepted Answer

Cyclosporine

Answer

Methotrexate

Answer

Hydroxychloroquine

Answer

Azathioprine

Question 6

Antipsychotic medications such as olanzapine affect OGTT results primarily through:

Accepted Answer

Weight gain and insulin resistance

Answer

Direct pancreatic beta-cell stimulation

Answer

Increased renal glucose clearance

Answer

GLP-1 receptor blockade