A patient with refractory chronic migraine is being considered for occipital nerve stimulation (ONS). What is the theoretical basis for its analgesic effect?
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A
Direct stimulation of the trigeminal nucleus caudalis via convergent pathways
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B
Suppression of cortical spreading depression at the occipital cortex
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C
Activation of the hypothalamic pain modulation center
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D
Blockade of C2 afferents entering the cervical cord