NCS Neurologic Pathophysiology

Question 1

Which neurotransmitter imbalance is primarily implicated in the pathophysiology of schizophrenia?

Accepted Answer

Excessive dopamine

Answer

Excessive serotonin

Answer

Deficient dopamine

Answer

Deficient norepinephrine

Question 2

In Huntington's disease, which of the following is the primary genetic mutation responsible for the condition?

Accepted Answer

Mutation in the HTT gene causing CAG repeat expansion

Answer

Mutation in the APP gene causing amyloid-beta deposition

Answer

Mutation in the PSEN1 gene causing tau hyperphosphorylation

Answer

Mutation in the SOD1 gene causing oxidative stress

Question 3

Which type of stroke is caused by the rupture of a blood vessel in the brain?

Accepted Answer

Hemorrhagic stroke

Answer

Ischemic stroke

Answer

Transient ischemic attack (TIA)

Answer

Subdural hematoma

Question 4

In multiple sclerosis (MS), which of the following is the primary pathophysiological process?

Accepted Answer

Demyelination of the central nervous system

Answer

Cortical neuron apoptosis

Answer

Autoimmune destruction of peripheral nerves

Answer

Excessive dopamine release in the basal ganglia

Question 5

Which neurodegenerative disease is primarily associated with the accumulation of amyloid-beta plaques and tau tangles in the brain?

Accepted Answer

Alzheimer's Disease

Answer

Multiple Sclerosis

Answer

Amyotrophic Lateral Sclerosis

Answer

Huntington’s Disease