NBRC Pharmacology and Therapeutics

Question 1

Which bronchodilator class acts primarily on beta-2 adrenergic receptors to cause bronchodilation?

Accepted Answer

Short-acting beta-2 agonists

Answer

Short-acting muscarinic antagonists

Answer

Methylxanthines

Answer

Leukotriene modifiers

Question 2

What is the primary mechanism of action of ipratropium bromide?

Accepted Answer

Muscarinic receptor blockade

Answer

Beta-2 receptor stimulation

Answer

Mast cell stabilization

Answer

Phosphodiesterase inhibition

Question 3

A patient with status asthmaticus is receiving continuous albuterol nebulization. Which adverse effect must be monitored most closely?

Accepted Answer

Hypokalemia

Answer

Hypernatremia

Answer

Metabolic acidosis

Answer

Hyperglycemia

Question 4

Which inhaled corticosteroid is most commonly used as maintenance therapy for persistent asthma?

Accepted Answer

Fluticasone

Answer

Prednisone

Answer

Methylprednisolone

Answer

Hydrocortisone

Question 5

What is the therapeutic serum level range for theophylline in adults?

Accepted Answer

10–20 mcg/mL

Answer

1–5 mcg/mL

Answer

5–10 mcg/mL

Answer

20–30 mcg/mL

Question 6

Dornase alfa (Pulmozyme) is primarily indicated for which condition?

Accepted Answer

Cystic fibrosis

Answer

Asthma exacerbations

Answer

COPD with chronic bronchitis

Answer

Pulmonary hypertension

Question 7

Which medication is classified as a long-acting beta-2 agonist (LABA)?

Accepted Answer

Salmeterol

Answer

Albuterol

Answer

Levalbuterol

Answer

Metaproterenol