MBBS Pathology 1

Question 1

Which type of necrosis is characteristically seen in tuberculosis?

Accepted Answer

Caseous necrosis

Answer

Tuberculosis produces caseous necrosis, which appears cheese-like grossly and consists of amorphous pink granular material microscopically.

Question 2

Reed-Sternberg cells are pathognomonic of which condition?

Accepted Answer

Hodgkin lymphoma

Answer

Reed-Sternberg cells (large binucleated cells with prominent 'owl eye' nucleoli) are the hallmark of Hodgkin lymphoma.

Question 3

Which tumor marker is elevated in hepatocellular carcinoma?

Accepted Answer

Alpha-fetoprotein (AFP)

Answer

AFP is elevated in approximately 70% of hepatocellular carcinoma cases and is also elevated in yolk sac tumors.

Question 4

What is the most common cause of right heart failure in the United States?

Accepted Answer

Left heart failure

Answer

Left heart failure leading to pulmonary hypertension and right ventricular pressure overload is the most common cause of right heart failure.

Question 5

Amyloid deposits in systemic amyloidosis are identified with which stain?

Accepted Answer

Congo red with apple-green birefringence under polarized light

Answer

Congo red stain identifies amyloid deposits, which show characteristic apple-green birefringence under polarized light microscopy.

MBBS - Bachelor of Medicine and Bachelor of Surgery Practice Test