A principle holds: 'Scientific claims should be accepted only when independently replicated.' A journal editor rejects a paper reporting a novel drug interaction. Which statement, if true, most directly justifies the rejection under this principle?
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A
The drug interaction would be commercially inconvenient for pharmaceutical companies.
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B
No other laboratory has reported this interaction despite studying the same drug combination.
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C
The paper's authors lack prestigious institutional affiliations.
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D
The interaction contradicts a well-established theory in pharmacology.