Laboratory Science Blood Banking and Transfusion Medicine 2

Question 1

Which Rh antigen is the most clinically significant and is the basis for Rh-positive/Rh-negative typing?

Accepted Answer

D antigen

Answer

The D antigen is the most immunogenic Rh antigen and determines whether a person is classified as Rh-positive or Rh-negative.

Question 2

What is the maximum allowable storage time for fresh frozen plasma (FFP) stored at -18°C or below?

Accepted Answer

1 year (12 months)

Answer

FFP stored at -18°C or below has a shelf life of 1 year; once thawed, it must be transfused within 24 hours.

Question 3

The weak D test is performed primarily to:

Accepted Answer

Detect weak expression of the D antigen in apparently Rh-negative individuals

Answer

Weak D testing identifies individuals with reduced or qualitatively different D antigen expression, preventing misclassification as Rh-negative.

Question 4

Leukoreduction of blood products is performed primarily to:

Accepted Answer

Reduce febrile non-hemolytic transfusion reactions and CMV transmission risk

Answer

Removing donor white blood cells reduces febrile non-hemolytic transfusion reactions caused by donor leukocyte antigens and cytokines, and decreases the risk of CMV transmission.

Question 5

What is the primary purpose of irradiating blood products before transfusion?

Accepted Answer

Prevent transfusion-associated graft-versus-host disease (TA-GvHD)

Answer

Irradiation inactivates donor T-lymphocytes, preventing them from engrafting and attacking tissues in immunocompromised recipients (TA-GvHD).

Laboratory Science Practice Test

Laboratory Science Practice Test

Laboratory Science Blood Banking and Transfusion Medicine 2