IBD IBD Nutrition and Lifestyle 2

Question 1

Cigarette smoking in Crohn's disease has which effect on disease course compared to UC?

Accepted Answer

Smoking worsens Crohn's disease (increases flares, need for surgery) while being paradoxically protective in UC

Answer

Smoking doubles the risk of Crohn's disease relapse, increases hospitalization and surgical rates, and worsens disease course — the opposite of its paradoxical protective effect in UC.

Question 2

Exercise in IBD patients with quiescent disease has been shown to have which effect?

Accepted Answer

Has anti-inflammatory effects, reduces fatigue, improves quality of life, and may reduce relapse risk

Answer

Regular moderate exercise has anti-inflammatory systemic effects, reduces IBD-related fatigue, improves psychological wellbeing, and emerging evidence suggests it may reduce relapse rates.

Question 3

Zinc deficiency is particularly common in Crohn's disease and manifests clinically with which symptom cluster?

Accepted Answer

Acrodermatitis enteropathica-like rash, poor wound healing, and impaired immune function

Answer

Zinc deficiency in Crohn's causes perioral and acral dermatitis (acrodermatitis enteropathica), impaired wound healing, taste/smell alterations, and immune dysfunction.

Question 4

Folate supplementation is particularly important for IBD patients on which medication to prevent macrocytic anemia?

Accepted Answer

Methotrexate

Answer

Methotrexate is a folate antagonist used in Crohn's disease; concurrent folic acid supplementation (1 mg/day) prevents methotrexate-related macrocytic anemia, mucositis, and hepatotoxicity.

Question 5

The specific carbohydrate diet (SCD) in IBD is based on which theoretical mechanism?

Accepted Answer

Restricting complex carbohydrates to starve pathogenic bacteria and improve gut dysbiosis

Answer

SCD restricts disaccharides, polysaccharides, and processed sugars theoretically used by pathogenic bacteria, aiming to restore a healthier gut microbiome composition.

IBD - Inflammatory Bowel Disease Practice Test

IBD - Inflammatory Bowel Disease Practice Test

IBD IBD Nutrition and Lifestyle 2