IBD IBD Complications and Extraintestinal Manifestations 2

Question 1

IBD-related uveitis (anterior uveitis) is potentially sight-threatening and requires which urgent management?

Accepted Answer

Urgent ophthalmology referral and topical corticosteroid eye drops

Answer

Anterior uveitis can cause permanent vision loss if untreated; urgent ophthalmology evaluation and topical steroids (with mydriatics) are required, independent of IBD disease activity.

Question 2

Short bowel syndrome (SBS) is a major risk in Crohn's disease after repeated intestinal resections when less than how much small bowel remains?

Accepted Answer

<200 cm

Answer

SBS typically occurs when less than 200 cm of functional small bowel remains, leading to malabsorption, electrolyte imbalances, and often dependence on parenteral nutrition.

Question 3

Which IBD complication presents with absolute right lower quadrant tenderness, fever, and CT showing a mesenteric mass with trapped bowel loops in Crohn's disease?

Accepted Answer

Intra-abdominal abscess

Answer

Intra-abdominal abscesses in Crohn's form from penetrating transmural inflammation creating mesenteric phlegmons or frank abscesses, requiring drainage and antibiotics before definitive surgery.

Question 4

Oxalate kidney stones in Crohn's disease result from which pathophysiological mechanism?

Accepted Answer

Increased intestinal oxalate absorption due to fat malabsorption binding calcium

Answer

Fat malabsorption causes luminal calcium to bind free fatty acids (saponification) rather than oxalate, leaving free oxalate available for hyperabsorption and renal deposition.

Question 5

Anemia in IBD is most commonly due to which combination of causes?

Accepted Answer

Iron deficiency anemia (chronic blood loss, malabsorption) and anemia of chronic inflammation

Answer

IBD anemia most commonly results from iron deficiency (chronic GI blood loss, impaired duodenal absorption) combined with anemia of chronic inflammation (hepcidin-mediated iron sequestration).

IBD - Inflammatory Bowel Disease Practice Test

IBD - Inflammatory Bowel Disease Practice Test

IBD IBD Complications and Extraintestinal Manifestations 2