HT Histology Laboratory Management 3

Question 1

A histotechnician is asked to dispose of used formalin fixative. Which regulation primarily governs proper disposal of this chemical?

Accepted Answer

Resource Conservation and Recovery Act (RCRA) as a hazardous waste

Answer

Formalin is regulated as a hazardous waste under RCRA, requiring proper manifesting and disposal through licensed hazardous waste contractors.

Question 2

Under CAP accreditation standards, how frequently must a histology laboratory perform and document calibration of its microtome blade-thickness settings?

Accepted Answer

According to manufacturer recommendations and laboratory policy, with documentation

Answer

CAP requires calibration per manufacturer recommendations and laboratory-defined policy, with records maintained; there is no universal mandated daily requirement.

Question 3

Which type of quality control material is MOST appropriate for monitoring day-to-day staining consistency in an H&E protocol?

Accepted Answer

Multi-tissue control block containing a variety of tissue types

Answer

A multi-tissue control block allows simultaneous assessment of staining characteristics across multiple tissue types, providing the broadest quality check for H&E.

Question 4

When developing a laboratory's chemical hygiene plan, which element is MANDATORY under OSHA's Laboratory Standard (29 CFR 1910.1450)?

Accepted Answer

Designation of a chemical hygiene officer

Answer

OSHA's Laboratory Standard requires that laboratories designate a chemical hygiene officer responsible for implementing and overseeing the chemical hygiene plan.

Question 5

A laboratory is adopting a new immunohistochemistry antibody clone. Which validation step determines the optimal antibody dilution?

Accepted Answer

Titration across multiple dilutions on known positive and negative tissues

Answer

Titration using serial dilutions on known positive and negative tissues identifies the dilution that provides optimal signal-to-noise ratio for the specific lab's conditions.

(HT) Histotechnician Certification Practice Test

(HT) Histotechnician Certification Practice Test

HT Histology Laboratory Management 3