General Surgery Board Review General Surgery Board Review MCQ 3 — Questions and Answers
Question 1: A 40-year-old woman has a thyroid nodule measuring 1.8 cm with microcalcifications and irregular margins on ultrasound. FNA shows papillary thyroid carcinoma. What is the most appropriate surgical treatment?
- Lobectomy only
- Total thyroidectomy (Correct answer)
- Total thyroidectomy with prophylactic central neck dissection
- Observation with repeat ultrasound
Correct answer: Total thyroidectomy
Total thyroidectomy is recommended for papillary thyroid carcinoma greater than 1 cm, allowing RAI therapy and simplifying surveillance with thyroglobulin monitoring.
Question 2: During a Whipple procedure, which of the following anastomoses is NOT performed?
- Pancreaticojejunostomy
- Hepaticojejunostomy
- Gastrojejunostomy
- Choledochoduodenostomy (Correct answer)
Correct answer: Choledochoduodenostomy
The Whipple (pancreaticoduodenectomy) includes pancreaticojejunostomy, hepaticojejunostomy, and gastrojejunostomy; the common bile duct is anastomosed to the jejunum, not the duodenum, which is resected.
Question 3: Which nutritional marker best reflects acute changes in a surgical patient's nutritional status over a 2- to 3-day period?
- Albumin
- Prealbumin (transthyretin) (Correct answer)
- Transferrin
- Total lymphocyte count
Correct answer: Prealbumin (transthyretin)
Prealbumin has a half-life of 2-3 days, making it the best short-term marker for acute nutritional changes, unlike albumin which has a 20-day half-life.
Question 4: A patient with a suspected sigmoid volvulus is hemodynamically stable without signs of peritonitis. What is the first-line treatment?
- Emergency sigmoid colectomy
- Flexible sigmoidoscopy with rectal tube decompression (Correct answer)
- CT-guided drainage
- Colonoscopy and surgical resection at the same sitting
Correct answer: Flexible sigmoidoscopy with rectal tube decompression
Flexible sigmoidoscopy with rectal tube placement achieves decompression in 70-90% of sigmoid volvulus cases and is the first-line treatment in stable patients without peritonitis.
Question 5: Which of the following is an absolute contraindication to laparoscopic appendectomy?
- Morbid obesity
- Prior lower abdominal surgery
- Uncorrected coagulopathy (Correct answer)
- Pregnancy in the third trimester
Correct answer: Uncorrected coagulopathy
Uncorrected coagulopathy is an absolute contraindication to any laparoscopic surgery due to uncontrollable bleeding risk; the other options are relative contraindications.
Question 6: A 65-year-old man has a 3 cm solitary liver lesion discovered incidentally. He has known cirrhosis and elevated AFP of 450 ng/mL. What is the most likely diagnosis?
- Hepatic hemangioma
- Hepatocellular carcinoma (Correct answer)
- Metastatic colorectal cancer
- Focal nodular hyperplasia
Correct answer: Hepatocellular carcinoma
A > 2 cm liver lesion with classic arterial enhancement on imaging in a cirrhotic patient plus elevated AFP is diagnostic of hepatocellular carcinoma by AASLD criteria.
Question 7: Which of the following findings on colonoscopy in a patient with ulcerative colitis is an indication for prophylactic proctocolectomy?
- Pseudopolyps
- Loss of haustra
- High-grade dysplasia confirmed on repeat biopsy (Correct answer)
- Backwash ileitis
Correct answer: High-grade dysplasia confirmed on repeat biopsy
High-grade dysplasia confirmed by expert pathology on repeat colonoscopy in ulcerative colitis warrants proctocolectomy due to the high risk of synchronous or future colorectal cancer.
A 40-year-old woman has a thyroid nodule measuring 1.8 cm with microcalcifications and irregular margins on ultrasound.
FNA shows papillary thyroid carcinoma.
What is the most appropriate surgical treatment?