Family Practice Exam Gastrointestinal Medicine 1

Question 1

Which of the following is the first-line treatment regimen for H. pylori eradication?

Accepted Answer

Triple therapy (PPI + amoxicillin + clarithromycin)

Answer

Triple therapy with a PPI, amoxicillin, and clarithromycin for 14 days is the standard first-line regimen for H. pylori eradication in areas with low clarithromycin resistance.

Question 2

A 45-year-old patient reports heartburn and regurgitation occurring at least twice weekly for 6 months. What is the most appropriate first-line pharmacological treatment?

Accepted Answer

Proton pump inhibitor (e.g., omeprazole)

Answer

PPIs provide superior acid suppression compared to H2 blockers and are the first-line pharmacological therapy for chronic GERD.

Question 3

According to Rome IV criteria, which of the following is NOT a diagnostic criterion for irritable bowel syndrome (IBS)?

Accepted Answer

Unintentional weight loss >10 lbs

Answer

Unintentional weight loss is a red-flag symptom suggesting organic disease and is not part of the Rome IV IBS criteria; its presence warrants further workup.

Question 4

Which antibody test is the preferred initial screening test for celiac disease in patients with adequate IgA levels?

Accepted Answer

Anti-tissue transglutaminase IgA (anti-tTG IgA)

Answer

Anti-tTG IgA is the single best screening test for celiac disease due to its high sensitivity (>95%) and specificity (~95%) and is recommended by all major guidelines.

Question 5

A 62-year-old otherwise healthy patient is diagnosed with uncomplicated acute diverticulitis (no abscess, no perforation, mild symptoms). What is the most appropriate management?

Accepted Answer

Outpatient treatment with oral antibiotics and liquid diet

Answer

Uncomplicated diverticulitis in immunocompetent patients with mild symptoms can be safely managed outpatient with oral antibiotics and dietary modification.

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Family Practice Exam Practice Test

Family Practice Exam Gastrointestinal Medicine 1