Family Practice Exam Gastrointestinal Medicine

Question 1

Which of the following is the first-line treatment regimen for H. pylori eradication?

Accepted Answer

Triple therapy (PPI + amoxicillin + clarithromycin)

Answer

PPI monotherapy for 8 weeks

Answer

Bismuth quadruple therapy alone

Answer

Metronidazole monotherapy for 14 days

Question 2

A 45-year-old patient reports heartburn and regurgitation occurring at least twice weekly for 6 months. What is the most appropriate first-line pharmacological treatment?

Accepted Answer

Proton pump inhibitor (e.g., omeprazole)

Answer

H2 receptor antagonist (e.g., famotidine)

Answer

Calcium-based antacid

Answer

Surgical fundoplication referral

Question 3

According to Rome IV criteria, which of the following is NOT a diagnostic criterion for irritable bowel syndrome (IBS)?

Accepted Answer

Unintentional weight loss >10 lbs

Answer

Recurrent abdominal pain at least 1 day per week for 3 months

Answer

Pain related to defecation

Answer

Pain associated with a change in stool frequency or form

Question 4

Which antibody test is the preferred initial screening test for celiac disease in patients with adequate IgA levels?

Accepted Answer

Anti-tissue transglutaminase IgA (anti-tTG IgA)

Answer

Anti-gliadin IgG

Answer

Anti-endomysial IgM

Answer

Anti-deamidated gliadin peptide IgM

Question 5

A 62-year-old otherwise healthy patient is diagnosed with uncomplicated acute diverticulitis (no abscess, no perforation, mild symptoms). What is the most appropriate management?

Accepted Answer

Outpatient treatment with oral antibiotics and liquid diet

Answer

Emergent surgical consultation for resection

Answer

Intravenous antibiotics with hospital admission

Answer

Urgent colonoscopy within 24 hours

Question 6

According to current USPSTF guidelines, at what age should average-risk asymptomatic adults begin colorectal cancer screening?

Accepted Answer

45 years

Answer

50 years

Answer

40 years

Answer

55 years

Question 7

Which of the following is the most common etiology of peptic ulcer disease in the United States?

Accepted Answer

Helicobacter pylori infection

Answer

Chronic NSAID use

Answer

Zollinger-Ellison syndrome

Answer

Stress-related mucosal disease