EDAIC Coagulation and Transfusion Medicine 2

Question 1

A trauma patient receives 10 units of packed red blood cells. Which electrolyte abnormality is most expected from massive transfusion?

Accepted Answer

Hyperkalemia

Answer

Stored red blood cells release potassium over time, leading to hyperkalemia with massive transfusion.

Question 2

Which test best reflects the extrinsic coagulation pathway?

Accepted Answer

Prothrombin time (PT)

Answer

Prothrombin time (PT) measures the extrinsic pathway (tissue factor/Factor VII) and common pathway.

Question 3

A patient on warfarin requires emergency reversal. Which agent provides the most rapid and complete reversal?

Accepted Answer

4-factor prothrombin complex concentrate (4F-PCC)

Answer

4-factor PCC provides immediate reversal of vitamin K antagonists with a smaller volume and faster effect than FFP.

Question 4

In heparin-induced thrombocytopenia (HIT), which anticoagulant is preferred for ongoing anticoagulation?

Accepted Answer

Argatroban

Answer

Argatroban is a direct thrombin inhibitor not derived from heparin and is safe to use in HIT.

Question 5

Which component of the massive transfusion protocol is primarily given to replace fibrinogen?

Accepted Answer

Cryoprecipitate

Answer

Cryoprecipitate is rich in fibrinogen, Factor VIII, von Willebrand factor, and Factor XIII.

EDAIC - European Diploma in Anesthesiology and Intensive Care Practice Test