DDS Oral Pathology and Oral Medicine

Question 1

Which odontogenic cyst is most commonly associated with an impacted mandibular third molar?

Accepted Answer

Dentigerous cyst

Answer

The dentigerous (follicular) cyst forms by fluid accumulation between the crown of an impacted tooth and its reduced enamel epithelium, most frequently around mandibular third molars.

Question 2

The term 'leukoplakia' in oral pathology refers to:

Accepted Answer

Any white patch of the oral mucosa that cannot be wiped off and cannot be diagnosed as any other disease

Answer

Leukoplakia is a clinical term for a white patch that cannot be rubbed off and cannot be characterized as any other definable disease, requiring biopsy for definitive diagnosis.

Question 3

Ameloblastoma is most commonly located in which area of the jaw?

Accepted Answer

Posterior mandible (molar-ramus region)

Answer

Approximately 80% of ameloblastomas occur in the mandible, with the majority in the posterior molar-ramus region.

Question 4

Which condition is characterized by numerous odontogenic keratocysts, basal cell carcinomas of the skin, and skeletal anomalies?

Accepted Answer

Gorlin syndrome (Nevoid basal cell carcinoma syndrome)

Answer

Gorlin syndrome (NBCCS) is caused by PTCH1 mutations and classically presents with multiple OKCs, basal cell carcinomas, calcified falx cerebri, and bifid ribs.

Question 5

Which virus is most strongly associated with hairy leukoplakia of the lateral tongue in immunocompromised patients?

Accepted Answer

Epstein-Barr virus (EBV)

Answer

Hairy leukoplakia is caused by EBV replication in superficial epithelial cells and is a marker of significant immune suppression, especially in HIV-positive patients.

DDS - Doctor of Dental Surgery Practice Test

DDS - Doctor of Dental Surgery Practice Test

DDS Oral Pathology and Oral Medicine