DAANCE Managing Systemic Diseases 4 — Questions and Answers
Question 1: A patient with poorly controlled type 2 diabetes presents for dental anesthesia. Which blood glucose range is generally considered acceptable for proceeding with elective sedation?
- Below 70 mg/dL
- 70–180 mg/dL (Correct answer)
- 180–250 mg/dL
- Above 250 mg/dL
Correct answer: 70–180 mg/dL
A fasting blood glucose of 70–180 mg/dL is generally accepted as safe for elective dental procedures under sedation.
Question 2: Which systemic condition most significantly increases the risk of laryngospasm during dental sedation due to airway hyperreactivity?
- Hypertension
- Asthma (Correct answer)
- Type 1 diabetes
- Hypothyroidism
Correct answer: Asthma
Asthma causes bronchial hyperreactivity, significantly raising the risk of laryngospasm and bronchospasm during sedation.
Question 3: A patient on warfarin for atrial fibrillation has an INR of 3.8 on the day of the procedure. What is the most appropriate action?
- Proceed with sedation as planned
- Administer vitamin K and proceed
- Postpone and consult with the patient's physician (Correct answer)
- Administer protamine sulfate
Correct answer: Postpone and consult with the patient's physician
An INR of 3.8 is supratherapeutic and poses significant bleeding risk; the procedure should be postponed pending physician guidance.
Question 4: During sedation, a patient with a known pheochromocytoma develops a sudden spike in blood pressure to 220/130 mmHg. Which drug is most appropriate for acute management?
- Metoprolol IV
- Phentolamine IV (Correct answer)
- Epinephrine IV
- Atropine IV
Correct answer: Phentolamine IV
Phentolamine, an alpha-adrenergic blocker, is the drug of choice for hypertensive crises caused by catecholamine excess from pheochromocytoma.
Question 5: A patient with end-stage renal disease on hemodialysis is scheduled for sedation. Which opioid is MOST SAFELY used due to inactive metabolites?
- Morphine
- Meperidine
- Fentanyl (Correct answer)
- Codeine
Correct answer: Fentanyl
Fentanyl is preferred in renal failure because its metabolites are inactive and do not accumulate to cause toxicity.
Question 6: Which ASA classification applies to a patient who has had a myocardial infarction within the past 30 days?
- ASA II
- ASA III
- ASA IV (Correct answer)
- ASA V
Correct answer: ASA IV
A recent myocardial infarction (within 30 days) represents a severe systemic disease with an immediate life threat, placing the patient in ASA IV.
Question 7: A patient with myasthenia gravis requires dental sedation. Which sedative/anesthetic interaction is of greatest concern?
- Benzodiazepines causing respiratory depression
- Ketamine causing bronchospasm
- Neuromuscular blocking agents causing prolonged paralysis (Correct answer)
- Nitrous oxide causing vitamin B12 depletion
Correct answer: Neuromuscular blocking agents causing prolonged paralysis
Patients with myasthenia gravis have abnormal neuromuscular junctions and are exquisitely sensitive to neuromuscular blocking agents, risking prolonged or profound paralysis.
A patient with poorly controlled type 2 diabetes presents for dental anesthesia.
Which blood glucose range is generally considered acceptable for proceeding with elective sedation?