DAANCE Anesthetic Pharmacology 2

Question 1

Midazolam is preferred over diazepam for IV sedation primarily because it:

Accepted Answer

Causes superior amnesia and has a shorter half-life

Answer

Has a longer duration of action

Answer

Does not cause respiratory depression

Answer

Is reversible with naloxone

Question 2

Flumazenil (Romazicon) reverses benzodiazepine sedation by:

Accepted Answer

Competitively blocking GABA-A receptor benzodiazepine sites

Answer

Stimulating endorphin release in the CNS

Answer

Inhibiting serotonin reuptake

Answer

Activating mu-opioid receptors

Question 3

Which opioid is most commonly used for IV conscious sedation in the dental office due to its rapid onset and short duration?

Accepted Answer

Fentanyl

Answer

Morphine

Answer

Meperidine (Demerol)

Answer

Codeine

Question 4

Nitrous oxide exerts its clinical effects primarily through:

Accepted Answer

NMDA receptor antagonism and endogenous opioid release

Answer

GABA-A receptor potentiation only

Answer

Alpha-2 adrenergic receptor agonism

Answer

Muscarinic acetylcholine receptor blockade

Question 5

A patient receiving IV ketamine for sedation is most likely to exhibit which distinctive clinical finding?

Accepted Answer

Dissociative anesthesia with preserved airway reflexes

Answer

Deep unconsciousness with absent reflexes

Answer

Respiratory depression requiring assisted ventilation

Answer

Profound bradycardia and hypotension

Question 6

The maximum recommended dose of epinephrine in a local anesthetic for a healthy adult per appointment is:

Accepted Answer

0.2 mg (200 mcg)

Answer

0.04 mg (40 mcg)

Answer

1.0 mg (1000 mcg)

Answer

2.0 mg (2000 mcg)