CRP Study Guide 2026
Everything you need to pass the CRP exam in one place: the exam format, every topic to study, real practice questions with explanations, flashcards, and full-length practice tests. Free, no sign-up needed.
📋 CRP Exam Format at a Glance
📚 CRP Topics to Study (69)
✍️ Sample CRP Questions & Answers
1. In program evaluation, 'stakeholder engagement' is considered important primarily because it:
Engaging stakeholders throughout the evaluation improves relevance, builds buy-in, and makes it far more likely that findings will inform decisions and actions.
2. A multi-site clinical trial uses a central IRB (cIRB) for review. Under the 2018 Revised Common Rule, which of the following is TRUE regarding cIRB use for domestic sites?
The 2018 Revised Common Rule mandates that domestic sites cooperating in multi-site research rely on a single IRB unless an exception is granted.
3. The counterfactual in an impact evaluation refers to:
The counterfactual represents the unobserved state — what outcomes would have looked like without the intervention — which is estimated through comparison groups.
4. Under 21 CFR Part 312, sponsors must report unexpected fatal or life-threatening suspected adverse reactions (IND safety reports) within:
FDA regulations require sponsors to report unexpected fatal or life-threatening suspected adverse reactions within 7 calendar days of initial receipt of information.
5. A clinical investigator receives an honorarium from a pharmaceutical company whose drug they are studying. Under 21 CFR Part 54, this financial relationship must be:
21 CFR Part 54 requires sponsors to certify or disclose investigators' financial interests to the FDA to allow assessment of potential bias in study data.
6. A qualitative researcher is studying domestic violence survivors. Which recruitment strategy raises the greatest ethical concern?
Recruiting from closed support groups can breach the confidentiality of members and may expose them to undue risk of identification.