CRP Cheat Sheet 2026

The 30 highest-yield CRP facts, distilled from real exam questions. Print it, save it as a PDF, or study it here — free, no sign-up.

1. How should a Certified Research Professional professional handle situations beyond their expertise? → Refer to a qualified specialist and communicate transparently with the client
2. In a longitudinal study tracking children's reading ability over 10 years, what is the primary concern with attrition? → Selection bias in the remaining sample
3. Which entity typically has authority to establish practice standards? → State licensing boards and professional regulatory bodies
4. Which principle ensures that research participants are treated as autonomous agents capable of making their own decisions? → Respect for Persons
5. Which research approach is characterized by generating theory from data collected in the field, rather than testing a pre-existing hypothesis? → Grounded theory
6. Which standard specifically governs the protection of personally identifiable information (PII) in federally funded research in the United States? → HIPAA Privacy Rule and the Common Rule (45 CFR 46)
7. In data documentation, 'contemporaneous' means the record should be made: → At the time the observation or action occurs
8. Which of the following is a common dissemination method? → Academic journal publication
9. Which GCP requirement is addressed by maintaining a 'delegation log' at a clinical research site? → Documenting which qualified staff members are authorized to perform specific trial tasks
10. What is the significance of professional networking in the Certified Research Professional field? → It facilitates knowledge exchange, referrals, and collaborative problem-solving
11. Who are typical audiences for research dissemination? → Academics, policy-makers, and the public
12. Which statistical measure is used to assess the internal consistency of a multi-item scale? → Cronbach's alpha
13. Which FDA form is used by sponsors and manufacturers to mandatorily report serious adverse events for marketed drugs? → MedWatch Form 3500A (Mandatory Reporting)
14. Under 21 CFR 312.32, a non-fatal, non-life-threatening unexpected serious adverse drug reaction must be reported to the FDA within: → 15 calendar days
15. A researcher conducting online surveys notices some respondents are completing surveys in unusually short times. The ethical response is to: → Flag and investigate these responses, removing confirmed speeders from analysis
16. Which Good Clinical Practice principle requires that all persons involved in conducting a trial be qualified by education, training, and experience? → The principle of qualified personnel
17. Which of the following BEST describes 'external validity'? → The extent to which findings can be generalized beyond the study sample
18. Which of the following best describes 'broad consent' as added by the 2018 Common Rule revision? → Consent for future unspecified research using stored biospecimens or data
19. In cost-benefit analysis, the 'net present value' (NPV) is used to: → Account for the time value of money when comparing future costs and benefits
20. What is the primary reason for maintaining source documents in clinical research? → To provide original records that verify the accuracy of data entered in the CRF
21. A client pressures a CRP to omit statistically significant but unfavorable findings from the final report. The researcher should: → Report all significant findings fully, regardless of client preference
22. How should risks be prioritized? → Based on probability of occurrence and potential impact
23. Which evaluation framework emphasizes the intended use by intended users as the primary criterion for evaluation design? → Utilization-focused evaluation
24. Which documentation practice best supports legal defensibility? → Objective, factual entries with specific measurements and timestamps
25. Which of the following scenarios represents a violation of research confidentiality? → Sharing a participant's identified responses with their employer
26. A researcher submits findings to a government agency without formal peer review. This type of document is known as: → Grey literature
27. Which research approach is most appropriate when the goal is to develop theory grounded in the systematic collection and analysis of qualitative data? → Grounded theory
28. Which principle from the Belmont Report directly underpins the informed consent requirement? → Respect for Persons
29. A researcher wants to use existing biobank samples without re-contacting donors. Under what condition is this ethically permissible without new consent? → The samples are fully de-identified per HIPAA Safe Harbor standards
30. When must a researcher submit a continuing review application to the IRB? → At intervals appropriate to the degree of risk, but at least annually