CRNI Antineoplastic and Biologic Therapies 3

Question 1

Which complication is MOST specifically associated with rituximab infusion therapy?

Accepted Answer

Tumor lysis syndrome

Answer

Rituximab can cause tumor lysis syndrome, particularly in patients with high tumor burden, due to rapid destruction of B-cells.

Question 2

When priming IV tubing for vesicant chemotherapy administration, what solution should be used?

Accepted Answer

Compatible IV fluid without the drug

Answer

IV tubing should be primed with compatible IV fluid rather than the chemotherapy drug to avoid waste of expensive medication and reduce exposure risk.

Question 3

A patient receiving an antineoplastic infusion develops urticaria and wheezing. After stopping the infusion, what is the priority nursing action?

Accepted Answer

Administer prescribed emergency medications

Answer

Urticaria and wheezing indicate an anaphylactic reaction requiring immediate administration of emergency medications such as epinephrine per standing orders.

Question 4

Which vascular access device is MOST appropriate for a chemotherapy regimen requiring intermittent infusions over 6 months?

Accepted Answer

Implanted port

Answer

An implanted port is ideal for intermittent long-term chemotherapy as it provides reliable central venous access with lower infection rates between treatments.

Question 5

What is the nurse's responsibility regarding hazardous drug spill management during an infusion?

Accepted Answer

Activate the spill kit, contain the area, and follow facility protocol

Answer

Hazardous drug spills require use of a dedicated spill kit with proper PPE and containment procedures as outlined in facility protocol.

CRNI Exam Practice Test

CRNI Exam Practice Test

CRNI Antineoplastic and Biologic Therapies 3