CRNI Antineoplastic and Biologic Therapies 3

Question 1

Which complication is MOST specifically associated with rituximab infusion therapy?

Accepted Answer

Tumor lysis syndrome

Answer

Hepatotoxicity

Answer

Peripheral neuropathy

Answer

Cardiotoxicity

Question 2

When priming IV tubing for vesicant chemotherapy administration, what solution should be used?

Accepted Answer

Compatible IV fluid without the drug

Answer

The chemotherapy drug itself

Answer

Sterile water for injection

Answer

Bacteriostatic normal saline

Question 3

A patient receiving an antineoplastic infusion develops urticaria and wheezing. After stopping the infusion, what is the priority nursing action?

Accepted Answer

Administer prescribed emergency medications

Answer

Document the reaction and notify the pharmacy

Answer

Obtain vital signs and call the physician

Answer

Restart the infusion at a slower rate

Question 4

Which vascular access device is MOST appropriate for a chemotherapy regimen requiring intermittent infusions over 6 months?

Accepted Answer

Implanted port

Answer

Peripheral IV catheter

Answer

Midline catheter

Answer

Short peripheral catheter with extension set

Question 5

What is the nurse's responsibility regarding hazardous drug spill management during an infusion?

Accepted Answer

Activate the spill kit, contain the area, and follow facility protocol

Answer

Clean the spill with standard cleaning supplies and document

Answer

Call environmental services and evacuate the room

Answer

Cover the spill with paper towels and continue the infusion

Question 6

When calculating the BSA-based dose of an antineoplastic agent, which patient measurement MUST be verified immediately before administration?

Accepted Answer

Current weight

Answer

Blood pressure

Answer

Oxygen saturation

Answer

Heart rate