CRNI Antineoplastic and Biologic Therapies 2

Question 1

Which vesicant chemotherapy agent requires immediate intervention if extravasation occurs during IV infusion?

Accepted Answer

Doxorubicin

Answer

Doxorubicin is a vesicant that can cause severe tissue necrosis if extravasation occurs, requiring immediate intervention including stopping the infusion and applying cold compresses.

Question 2

When administering biologic response modifiers, which nursing assessment is MOST critical during the first 30 minutes?

Accepted Answer

Monitoring for anaphylactic reactions

Answer

Biologic agents such as monoclonal antibodies carry the highest risk of infusion reactions and anaphylaxis during the first 30 minutes of administration.

Question 3

What is the recommended action when a patient receiving a cytotoxic infusion reports burning at the IV site?

Accepted Answer

Stop the infusion immediately and assess the site

Answer

Burning at the IV site during cytotoxic infusion suggests possible extravasation, requiring immediate cessation of the infusion and thorough site assessment.

Question 4

Which personal protective equipment (PPE) is required when handling antineoplastic agents according to current INS standards?

Accepted Answer

Double chemotherapy-tested gloves, gown, and face shield

Answer

Current standards require double gloving with chemotherapy-tested gloves, a protective gown, and face/eye protection when handling antineoplastic agents to prevent occupational exposure.

Question 5

A patient is prescribed a targeted therapy infusion. Which laboratory value should be monitored MOST closely during treatment?

Accepted Answer

Complete blood count with differential

Answer

Targeted therapies frequently cause myelosuppression, making CBC with differential essential for monitoring neutropenia, thrombocytopenia, and anemia.

CRNI Exam Practice Test

CRNI Exam Practice Test

CRNI Antineoplastic and Biologic Therapies 2