CRNI Antineoplastic and Biologic Therapies 2

Question 1

Which vesicant chemotherapy agent requires immediate intervention if extravasation occurs during IV infusion?

Accepted Answer

Doxorubicin

Answer

Cyclophosphamide

Answer

Methotrexate

Answer

Bleomycin

Question 2

When administering biologic response modifiers, which nursing assessment is MOST critical during the first 30 minutes?

Accepted Answer

Monitoring for anaphylactic reactions

Answer

Blood pressure monitoring every 15 minutes

Answer

Assessing urine output

Answer

Checking blood glucose levels

Question 3

What is the recommended action when a patient receiving a cytotoxic infusion reports burning at the IV site?

Accepted Answer

Stop the infusion immediately and assess the site

Answer

Slow the infusion rate and continue monitoring

Answer

Apply a warm compress and continue the infusion

Answer

Flush the line with normal saline and resume

Question 4

Which personal protective equipment (PPE) is required when handling antineoplastic agents according to current INS standards?

Accepted Answer

Double chemotherapy-tested gloves, gown, and face shield

Answer

Sterile gloves only

Answer

Standard exam gloves and mask

Answer

Sterile gown and single pair of gloves

Question 5

A patient is prescribed a targeted therapy infusion. Which laboratory value should be monitored MOST closely during treatment?

Accepted Answer

Complete blood count with differential

Answer

Serum calcium levels

Answer

Serum albumin

Answer

Prothrombin time

Question 6

What is the maximum recommended time frame for use of a closed-system transfer device (CSTD) when preparing hazardous drugs?

Accepted Answer

Within the beyond-use date specified by the manufacturer

Answer

Use once and discard

Answer

Up to 24 hours after initial use

Answer

Until the device shows visible damage