CPhT Compounding 5

Question 1

Which type of water is required for reconstituting parenteral preparations in sterile compounding?

Accepted Answer

Sterile Water for Injection USP

Answer

Sterile Water for Injection (SWFI) USP is the standard diluent for parenteral products because it is both purified and rendered sterile and pyrogen-free.

Question 2

A compounded transdermal gel is prepared using PLO (pluronic lecithin organogel). The purpose of PLO is to:

Accepted Answer

Enhance penetration of the drug through the skin

Answer

PLO is a lipophilic gel base that facilitates transdermal drug absorption by improving drug penetration through the stratum corneum.

Question 3

Before discarding a returned or unused compounded hazardous drug preparation, the pharmacy technician should:

Accepted Answer

Dispose of it via an EPA-compliant pharmaceutical waste vendor or reverse distributor

Answer

Hazardous drug waste must be disposed of through regulated channels (e.g., Pharmaceutical Waste Rule-compliant containers and vendors) to protect public and environmental health.

Question 4

Osmolarity is a critical parameter when compounding ophthalmic preparations because:

Accepted Answer

Solutions outside the isotonic range (approximately 285–310 mOsm/L) cause irritation or damage to ocular tissue

Answer

Ophthalmic preparations must be near isotonic (approximately 285–310 mOsm/L) to avoid pain, irritation, and cellular damage to the delicate eye tissues.

Question 5

Which of the following represents a correct first-air principle when working inside a laminar airflow workbench (LAFW)?

Accepted Answer

Never allow any object to interrupt the unidirectional airflow path between the HEPA filter and an open critical site

Answer

First-air is the uncontaminated air directly from the HEPA filter; no object, including hands, should block this air from reaching an open vial, needle, or syringe tip.

(CPhT) Certified Pharmacy Technician Practice Test

(CPhT) Certified Pharmacy Technician Practice Test

CPhT Compounding 5