CPhT Compounding 2

Question 1

Which beyond-use date (BUD) applies to an unpreserved aqueous oral solution compounded in a non-sterile environment under USP <795>?

Accepted Answer

14 days refrigerated

Answer

USP <795> assigns unpreserved aqueous oral solutions a BUD of 14 days when stored under refrigeration.

Question 2

When compounding a suppository base, cocoa butter is classified as what type of base?

Accepted Answer

Fatty (oleaginous) base

Answer

Cocoa butter is a classic fatty (oleaginous) suppository base that melts at body temperature.

Question 3

A pharmacy technician is preparing a 2% salicylic acid ointment using fusion. Which step is MOST critical to product uniformity?

Accepted Answer

Adding the drug to the fully melted base with constant stirring during cooling

Answer

Constant stirring while the mixture cools prevents drug particle settling and ensures uniform distribution.

Question 4

Which piece of equipment is used to measure small volumes of liquid (0.1–1 mL) most accurately during non-sterile compounding?

Accepted Answer

Syringe

Answer

Syringes are more accurate than graduates for volumes under 1 mL due to their narrow bore and precise graduations.

Question 5

In the context of compounding, what does 'levigation' mean?

Accepted Answer

Reducing particle size by triturating with a small amount of liquid

Answer

Levigation reduces particle size by triturating the powder with a levigating agent (e.g., glycerin) to form a smooth paste.

(CPhT) Certified Pharmacy Technician Practice Test