Chemotherapy Administration and Safety Flashcards
6 cards from real CPHON practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 6 Chemotherapy Administration and Safety flashcards as text
Which personal protective equipment (PPE) is MOST important when administering intravenous vesicant chemotherapy to a pediatric patient?
Answer: Double gloves and a gown
Double gloves and a gown are required when handling vesicant chemotherapy agents to protect the nurse from skin exposure.
A child receiving vincristine develops jaw pain and peripheral tingling. The nurse recognizes these as signs of:
Answer: Peripheral neuropathy
Vincristine is a known neurotoxin; jaw pain and peripheral tingling are hallmark signs of vinca alkaloid-induced peripheral neuropathy.
When preparing to administer intrathecal chemotherapy to a child, which action is MOST critical?
Answer: Verify the drug with a second licensed nurse
Intrathecal chemotherapy must be verified by two licensed nurses because errors can be immediately life-threatening.
A nurse notices swelling and burning at a child's IV site during doxorubicin infusion. The FIRST action should be:
Answer: Stop the infusion immediately and disconnect the IV
Stopping the infusion immediately and disconnecting the IV prevents further tissue exposure to the vesicant agent.
Which chemotherapy agent requires prehydration and mesna to prevent hemorrhagic cystitis?
Answer: Ifosfamide
Ifosfamide is metabolized to acrolein, which is toxic to the bladder; mesna binds acrolein and prehydration dilutes it.
A child on high-dose methotrexate has a serum methotrexate level of 10 micromol/L at 24 hours. The nurse should anticipate administering:
Answer: Leucovorin rescue
Leucovorin (folinic acid) is the rescue agent for methotrexate toxicity, bypassing the enzyme methotrexate inhibits.