COT Study Guide 2026

Everything you need to pass the COT exam in one place: the exam format, every topic to study, real practice questions with explanations, flashcards, and full-length practice tests. Free, no sign-up needed.

📋 COT Exam Format at a Glance

200
Questions
180 min
Time Limit
72.00%
Passing Score

📚 COT Topics to Study (176)

✍️ Sample COT Questions & Answers

1. Which slit-lamp illumination technique is best for detecting corneal edema and stromal haze?
Sclerotic scatter

Sclerotic scatter illuminates the cornea via total internal reflection from the limbus, making stromal haze and edema visible as a glow against a dark background.

2. Which topical ophthalmic antibiotic is a fluoroquinolone commonly used to treat bacterial conjunctivitis and corneal ulcers?
Ciprofloxacin

Ciprofloxacin is a broad-spectrum fluoroquinolone antibiotic that inhibits bacterial DNA gyrase and is effective against both gram-positive and gram-negative organisms causing ocular infections.

3. The foveal avascular zone (FAZ) receives its oxygen supply primarily through which mechanism?
Diffusion from the underlying choriocapillaris

The FAZ is devoid of retinal capillaries by definition. The foveal photoreceptors — the most metabolically demanding cells in the retina — rely entirely on diffusion of oxygen and nutrients from the choriocapillaris across Bruch's membrane and the retinal pigment epithelium. This is why macular degeneration, which disrupts the choriocapillaris, is so devastating to central vision.

4. What is the focal length of a +4.00 D lens?
0.25 meters

Focal length (f) = 1 / power in diopters = 1 / 4.00 = 0.25 meters.

5. On a properly aligned A-scan, the retinal spike should be:
Sharp and perpendicular (90°) with high amplitude

A perpendicular, high-amplitude retinal spike indicates the probe is aligned along the visual axis and measurement is accurate.

6. If a spectacle Rx is −10.00 D at a vertex distance of 12 mm, what is the approximate contact lens power needed?
−9.00 D

For high minus lenses, moving the lens to the cornea reduces effective power; the CL power is approximately −9.00 D at the corneal plane.

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Your COT Study Path
1. Learn with Flashcards → 2. Drill Practice Tests → 3. Take the Full Exam Simulation
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