CMT CMT Blood Banking and Transfusion Medicine 2

Question 1

A transfusion reaction presenting with fever, chills, and flank pain minutes after starting a transfusion most suggests:

Accepted Answer

Acute hemolytic transfusion reaction

Answer

Fever, chills, and flank pain (from renal involvement) occurring rapidly after transfusion onset are classic signs of an acute hemolytic transfusion reaction due to ABO incompatibility.

Question 2

Which test is performed to detect unexpected alloantibodies in a patient's plasma before transfusion?

Accepted Answer

Antibody screen (indirect antiglobulin test)

Answer

The antibody screen (indirect antiglobulin test) tests the patient's serum against reagent red cells expressing known antigens to detect unexpected alloantibodies.

Question 3

Cryoprecipitate is the product of choice for which deficiency?

Accepted Answer

Fibrinogen deficiency or von Willebrand disease

Answer

Cryoprecipitate is rich in fibrinogen, Factor VIII, von Willebrand factor, and Factor XIII, making it the preferred product for fibrinogen deficiency and vWD.

Question 4

Irradiation of blood products is performed primarily to prevent:

Accepted Answer

Transfusion-associated graft-versus-host disease (TA-GvHD)

Answer

Gamma irradiation inactivates donor T lymphocytes in blood products, preventing them from engrafting and attacking the immunocompromised recipient in TA-GvHD.

Question 5

The Kleihauer-Betke test is used to:

Accepted Answer

Detect fetal-maternal hemorrhage by quantifying fetal cells in maternal blood

Answer

The Kleihauer-Betke acid elution test differentiates fetal (HbF-containing) from adult red cells in maternal blood to estimate the degree of feto-maternal hemorrhage and guide Rh immunoglobulin dosing.

CMT - Certified Medical Technologist Practice Test

CMT - Certified Medical Technologist Practice Test

CMT CMT Blood Banking and Transfusion Medicine 2