Mixed Deck — All CETP Topics Flashcards

What is the correct technique when withdrawing medication from a vial using a needle and syringe?

Answer: Inject air equal to the volume to be withdrawn, then withdraw the medication

Injecting air equal to the desired withdrawal volume creates positive pressure inside the vial, facilitating smooth and accurate medication withdrawal.

A patient taking methotrexate for rheumatoid arthritis requires antibiotic therapy. Which antibiotic combination carries the highest risk of serious methotrexate toxicity?

Answer: Trimethoprim-sulfamethoxazole (TMP-SMX)

TMP-SMX inhibits renal tubular secretion of methotrexate (raising its levels) and also inhibits dihydrofolate reductase synergistically with methotrexate, dramatically increasing bone marrow suppression toxicity.

What is informed consent in the context of Canadian Entry To Practice?

Answer: Ensuring all parties understand and agree to terms before proceeding

Informed consent means providing all relevant information so that parties can make knowledgeable decisions. It requires clear communication of risks, benefits, alternatives, and procedures.

Digoxin toxicity risk increases significantly when which electrolyte imbalance is caused by a concomitant medication?

Answer: Hypokalemia

Hypokalemia increases the binding of digoxin to Na+/K+-ATPase and enhances its toxic effects; loop and thiazide diuretics can precipitate this interaction by causing potassium wasting.

Which USP chapter provides the standards for sterile compounding in pharmacy practice?

Answer: USP

USP establishes the standards for compounded sterile preparations including environmental requirements, beyond-use dates, and personnel competency.

Which approach is most effective for mastering compounding in Canadian Entry To Practice?

Answer: Combining theoretical study with practical application and regular review

The most effective approach combines theoretical understanding with practical application, reinforced by regular review and assessment, enabling deeper comprehension and long-term retention.

Which of the following is a main principle of the Canada Health Act?

Answer: Eligible Canadians should receive accessible health care.

One of the Canada Health Act's goals was to provide accessible health care to eligible Canadians.

In Canadian Entry To Practice, what role does continuing education play in pharmacology?

Answer: To keep professionals current with evolving standards, technologies, and best practices

Continuing education ensures professionals stay current with new developments, evolving standards, and emerging best practices in their field, maintaining competence throughout their careers.

What is the primary objective of quality assurance in Canadian Entry To Practice?

Answer: To ensure competence and proficiency in core quality assurance concepts

The primary objective of quality assurance knowledge is to ensure practitioners have the competence and proficiency needed to perform effectively and safely in their professional roles.

What is the consequence of non-compliance with regulations in Canadian Entry To Practice?

Answer: Potential penalties including fines, license revocation, and legal liability

Non-compliance can result in serious consequences including financial penalties, loss of professional licensure, legal liability, reputational damage, and in some cases criminal prosecution.

Which management approach in Canadian Entry To Practice emphasizes continuous improvement through small, incremental changes?

Answer: Kaizen methodology

Kaizen is a Japanese management philosophy that focuses on continuous improvement through small, incremental changes involving all employees, leading to sustained improvement over time.

How is the holistic model of health described?

Answer: It is a model that considers all parts of the person.

The holistic model of health considers all parts of the person. For example, when a client has newly diagnosed hypertension, health professionals will consider weight, risk behaviors, diet, stress and ability to follow a medication regime.

How should cytotoxic waste generated during sterile compounding be disposed of?

Answer: In designated yellow chemotherapy waste containers per institutional protocols

Cytotoxic waste must be placed in designated chemotherapy waste containers following regulatory guidelines to protect personnel and minimize environmental contamination.

In 1834, William Kelly deduced which public health principle?

Answer: Sanitation and disease are related

William Kelly suspected a relationship between sanitation and disease and deduced that water might be a source of contamination

What is a pharmacy manager's primary responsibility when a drug recall notice is received?

Answer: Identify and quarantine all affected product lots, notify affected patients if required, and document all actions taken

Upon receiving a recall notice, the pharmacy manager must immediately identify, quarantine, and return affected products and notify patients when required by the recall class.

In Canadian Entry To Practice, what is the primary purpose of regulatory compliance?

Answer: To ensure adherence to laws, rules, and standards that govern the profession

Regulatory compliance ensures that organizations and professionals follow all applicable laws, regulations, and standards, protecting the public and maintaining professional integrity.

What is the primary objective of pharmacology in Canadian Entry To Practice?

Answer: To ensure competence and proficiency in core pharmacology concepts

The primary objective of pharmacology knowledge is to ensure practitioners have the competence and proficiency needed to perform effectively and safely in their professional roles.

In Canadian Entry To Practice, what role does an audit serve in regulatory compliance?

Answer: To systematically examine and verify compliance with regulations and standards

Audits provide systematic, independent examination of processes, records, and activities to verify compliance with applicable regulations, standards, and internal policies.

Which enzyme system is primarily responsible for metabolizing the majority of drugs, making it the most common site of pharmacokinetic drug-drug interactions?

Answer: Cytochrome P450 (CYP) system

The cytochrome P450 enzyme system in the liver metabolizes approximately 70-80% of all drugs, making it the most frequent source of clinically significant drug-drug interactions.

Dopamine antagonists (e.g., metoclopramide, haloperidol) reduce the therapeutic efficacy of which medication used in Parkinson's disease?

Answer: Levodopa/carbidopa

Dopamine antagonists block dopamine receptors in the striatum, directly opposing the mechanism of levodopa, thereby reducing its antiparkinsonian effects.