CETP Sterile Preparations Flashcards

What is the primary purpose of a laminar airflow workbench (LAFW) in sterile compounding?

Answer: To provide a sterile environment by directing HEPA-filtered air across the work surface

A laminar airflow workbench uses HEPA-filtered unidirectional airflow to maintain an ISO Class 5 sterile environment for preparing sterile products.

Which ISO classification is required for the critical zone in sterile compounding?

Answer: ISO Class 5

ISO Class 5 (≤3,520 particles ≥0.5 µm per cubic meter) is required for the critical zone where sterile preparations are made.

What is the beyond-use date (BUD) for a low-risk compounded sterile preparation stored at room temperature per USP ?

Answer: 48 hours

USP specifies that low-risk compounded sterile preparations have a BUD of 48 hours at controlled room temperature.

What is the correct technique for removing air bubbles from a syringe prior to injection?

Answer: Tap the syringe to collect bubbles at the tip, then expel them

Tapping the syringe consolidates air bubbles at the tip, which are then expelled to ensure accurate dose delivery.

What is the purpose of fingertip sampling in sterile compounding personnel qualification?

Answer: To evaluate the effectiveness of personnel aseptic technique

Fingertip sampling tests assess whether compounding personnel are maintaining proper aseptic technique during sterile preparation activities.

Which of the following medications is classified as a high-alert medication requiring extra precautions during sterile preparation?

Answer: Concentrated potassium chloride

Concentrated potassium chloride is an ISMP high-alert medication that can cause fatal cardiac arrhythmias if administered incorrectly or undiluted.