CETP Sterile Preparations Flashcards

What is the purpose of end-product sterility testing in sterile compounding?

Answer: To confirm the absence of viable microbial contamination in the final product

End-product sterility testing confirms that the compounded sterile preparation is free from viable microorganisms before it reaches the patient.

What is the correct aseptic transfer technique when adding medication to an intravenous bag?

Answer: Wipe the port with 70% IPA, allow it to dry, then inject the medication

Wiping the injection port with 70% IPA and allowing it to air-dry before injection removes surface contaminants and reduces microbial transfer risk.

What is the primary safety concern when preparing parenteral nutrition (PN) solutions?

Answer: Risk of chemical precipitation and microbial contamination

Parenteral nutrition solutions risk calcium-phosphate precipitation and support microbial growth due to their nutrient-rich composition.

How should cytotoxic waste generated during sterile compounding be disposed of?

Answer: In designated yellow chemotherapy waste containers per institutional protocols

Cytotoxic waste must be placed in designated chemotherapy waste containers following regulatory guidelines to protect personnel and minimize environmental contamination.

Which USP chapter provides the standards for sterile compounding in pharmacy practice?

Answer: USP

USP establishes the standards for compounded sterile preparations including environmental requirements, beyond-use dates, and personnel competency.

What is the recommended hand hygiene procedure before beginning sterile compounding activities?

Answer: Wash hands for at least 30 seconds with soap and water, then apply 70% IPA

At least 30 seconds of soap-and-water handwashing followed by 70% IPA application provides both mechanical removal and chemical kill of microorganisms.