Practice Test GeeksCCTN - Certified Clinical Transplant Nurse Practice Test
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Transplant Complications and Clinical Management Flashcards

6 cards from real CCTN practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.

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  1. A kidney transplant patient presents with fever, graft tenderness, and rising serum creatinine 10 days post-transplant. What is the most likely diagnosis?

    Answer: Acute cellular rejection

    Fever, graft tenderness, and rising creatinine in the first weeks post-transplant are classic signs of acute cellular rejection requiring biopsy confirmation.

  2. Post-transplant lymphoproliferative disorder (PTLD) is most strongly associated with which viral infection?

    Answer: Epstein-Barr Virus (EBV)

    PTLD is most strongly associated with Epstein-Barr Virus (EBV), particularly in EBV-naive recipients receiving organs from EBV-seropositive donors.

  3. BK virus nephropathy in renal transplant recipients is managed primarily by which intervention?

    Answer: Reducing immunosuppression to allow immune control of the virus

    BK nephropathy is managed by reducing immunosuppression to allow the recipient's immune system to control BK virus replication and limit nephropathy progression.

  4. Which complication is indicated by a sudden cessation of urine output, graft pain, and hematuria in an early post-kidney-transplant patient?

    Answer: Renal vein thrombosis

    Sudden anuria with graft pain and hematuria in the early post-transplant period suggests renal vein thrombosis, a surgical emergency requiring immediate intervention.

  5. What is the recommended prophylaxis for Pneumocystis jirovecii pneumonia (PJP) in solid organ transplant recipients?

    Answer: Trimethoprim-sulfamethoxazole (TMP-SMX)

    TMP-SMX (Bactrim) is the first-line prophylaxis for PJP in transplant recipients and also provides coverage against Toxoplasma and some urinary tract pathogens.

  6. A transplant patient on tacrolimus and TMP-SMX develops hyperkalemia. What is the most likely cause?

    Answer: Combined effect of tacrolimus and TMP-SMX on renal potassium excretion

    Both tacrolimus and TMP-SMX reduce renal potassium excretion through different mechanisms, and their combination commonly causes hyperkalemia in transplant recipients.

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