CCRN Sepsis and MODS 3

Question 1

Multiple organ dysfunction syndrome (MODS) is best defined as:

Accepted Answer

Progressive dysfunction of two or more organ systems requiring intervention to maintain homeostasis

Answer

MODS involves altered function of two or more organ systems requiring support.

Question 2

Which organ system is typically the first to fail in the progression of MODS?

Accepted Answer

Pulmonary (lungs)

Answer

The lungs are often the first organ to fail, frequently presenting as ARDS.

Question 3

Sepsis-associated acute kidney injury is most directly indicated by which finding?

Accepted Answer

Rising creatinine with decreased urine output

Answer

AKI is marked by rising creatinine and oliguria reflecting reduced renal function.

Question 4

Which coagulation abnormality is a hallmark of disseminated intravascular coagulation (DIC) in severe sepsis?

Accepted Answer

Simultaneous bleeding and microvascular thrombosis

Answer

DIC produces both clotting and bleeding due to consumption of clotting factors.

Question 5

In sepsis-induced hepatic dysfunction, which laboratory finding is commonly seen?

Accepted Answer

Rising bilirubin and transaminases

Answer

Hepatic dysfunction raises bilirubin and liver enzymes and prolongs the INR.

CCRN Review Practice Test