CCP Drug Therapy Management 2

Question 1

An elderly patient with heart failure is prescribed spironolactone. Which monitoring parameter is most critical?

Accepted Answer

Serum potassium

Answer

Spironolactone is a potassium-sparing diuretic that can cause hyperkalemia, which is especially dangerous in heart failure patients.

Question 2

A consultant pharmacist identifies that a nursing home resident on warfarin has an INR of 4.8 with no signs of bleeding. What is the most appropriate initial intervention?

Accepted Answer

Hold warfarin and recheck INR in 1-2 days

Answer

For supratherapeutic INR without serious bleeding, holding warfarin and rechecking the INR in 1-2 days is the standard approach per CHEST guidelines.

Question 3

Which medication class is considered first-line therapy for reducing cardiovascular events in type 2 diabetes patients with established atherosclerotic cardiovascular disease?

Accepted Answer

GLP-1 receptor agonists or SGLT-2 inhibitors

Answer

ADA guidelines recommend GLP-1 receptor agonists or SGLT-2 inhibitors with proven cardiovascular benefit as preferred add-on therapy in T2DM with ASCVD.

Question 4

A patient taking methotrexate for rheumatoid arthritis should receive supplementation with which vitamin to reduce toxicity?

Accepted Answer

Folic acid

Answer

Folic acid supplementation reduces methotrexate-associated adverse effects such as mucositis, nausea, and hepatotoxicity without reducing efficacy.

Question 5

Which antibiotic class is associated with QT prolongation and should be used cautiously in patients on antipsychotics?

Accepted Answer

Fluoroquinolones

Answer

Fluoroquinolones prolong the QT interval and can have an additive effect when combined with antipsychotics, increasing the risk of torsades de pointes.

(CCP) Certified Consultant Pharmacist Practice Test

(CCP) Certified Consultant Pharmacist Practice Test

CCP Drug Therapy Management 2