CCP Drug Therapy Management 2

Question 1

An elderly patient with heart failure is prescribed spironolactone. Which monitoring parameter is most critical?

Accepted Answer

Serum potassium

Answer

Serum sodium

Answer

Blood glucose

Answer

Liver enzymes

Question 2

A consultant pharmacist identifies that a nursing home resident on warfarin has an INR of 4.8 with no signs of bleeding. What is the most appropriate initial intervention?

Accepted Answer

Hold warfarin and recheck INR in 1-2 days

Answer

Administer vitamin K 10 mg IV immediately

Answer

Continue current dose and recheck in 1 week

Answer

Discontinue warfarin permanently

Question 3

Which medication class is considered first-line therapy for reducing cardiovascular events in type 2 diabetes patients with established atherosclerotic cardiovascular disease?

Accepted Answer

GLP-1 receptor agonists or SGLT-2 inhibitors

Answer

Sulfonylureas

Answer

Alpha-glucosidase inhibitors

Answer

Thiazolidinediones

Question 4

A patient taking methotrexate for rheumatoid arthritis should receive supplementation with which vitamin to reduce toxicity?

Accepted Answer

Folic acid

Answer

Vitamin B12

Answer

Vitamin D

Answer

Vitamin C

Question 5

Which antibiotic class is associated with QT prolongation and should be used cautiously in patients on antipsychotics?

Accepted Answer

Fluoroquinolones

Answer

Penicillins

Answer

Tetracyclines

Answer

Aminoglycosides

Question 6

A long-term care resident on bisphosphonate therapy for osteoporosis reports new jaw pain following a dental procedure. What condition should be suspected?

Accepted Answer

Osteonecrosis of the jaw

Answer

Trigeminal neuralgia

Answer

Temporomandibular joint disorder

Answer

Pericoronitis

Question 7

Which pharmacokinetic change associated with aging most significantly affects the dosing of lipid-soluble drugs in elderly patients?

Accepted Answer

Increased volume of distribution due to increased body fat

Answer

Decreased volume of distribution due to decreased body fat

Answer

Increased renal clearance

Answer

Decreased protein binding