CCI Cardiac Pharmacology and Hemodynamic Monitoring 2

Question 1

Which invasive hemodynamic measurement is obtained by the thermodilution technique using a pulmonary artery (Swan-Ganz) catheter?

Accepted Answer

Cardiac output

Answer

Thermodilution cardiac output is measured by injecting cold saline into the right atrium and detecting the temperature change downstream in the pulmonary artery to calculate flow.

Question 2

In the Fick method for cardiac output calculation, what three variables are required?

Accepted Answer

Oxygen consumption, arterial O₂ content, and mixed venous O₂ content

Answer

The Fick principle states CO = VO₂ / (CaO₂ – CvO₂), requiring whole-body oxygen consumption, arterial oxygen content, and mixed venous oxygen content.

Question 3

Which pharmacologic agent is a phosphodiesterase-3 inhibitor used for short-term IV support in decompensated heart failure?

Accepted Answer

Milrinone

Answer

Milrinone inhibits phosphodiesterase-3, increasing cAMP, leading to positive inotropy and vasodilation (inodilator), used for short-term support in acute decompensated heart failure.

Question 4

What is the primary indication for using adenosine during cardiac catheterization for fractional flow reserve (FFR) measurement?

Accepted Answer

To induce maximal coronary hyperemia for accurate pressure gradient measurement

Answer

Adenosine induces maximal coronary hyperemia by maximally dilating the coronary microvasculature, which is required to accurately calculate FFR from the pressure gradient across a stenosis.

Question 5

Which hemodynamic profile best describes cardiogenic shock?

Accepted Answer

High PCWP, high SVR, low cardiac output

Answer

Cardiogenic shock presents with elevated PCWP (congestion), compensatory high SVR (vasoconstriction), and low cardiac output reflecting pump failure.

CCI - Cardiovascular Credentialing International Practice Test

CCI - Cardiovascular Credentialing International Practice Test

CCI Cardiac Pharmacology and Hemodynamic Monitoring 2