BMAT Technology & Digital Applications 4

Question 1

CRISPR-Cas9 gene editing uses guide RNA (gRNA) to direct the Cas9 protein to a target DNA site. The gRNA is designed to be complementary to:

Accepted Answer

The specific DNA sequence to be cut

Answer

The gRNA is engineered with a sequence complementary to the target genomic DNA, guiding Cas9 to create a double-strand break at that precise location.

Question 2

In pharmacogenomics, cytochrome P450 (CYP) enzyme polymorphisms are clinically important because they affect:

Accepted Answer

Drug metabolism rates and optimal dosing

Answer

CYP enzyme variants cause patients to metabolize drugs at different rates, making genotyping essential for personalized dosing to avoid toxicity or treatment failure.

Question 3

Which technology generates three-dimensional anatomical models from CT or MRI data for pre-surgical planning?

Accepted Answer

3D printing / additive manufacturing

Answer

Patient-specific CT/MRI DICOM data can be segmented and converted into STL files for 3D printing of anatomical replicas used in surgical rehearsal.

Question 4

A smartphone application monitors a diabetic patient's glucose via a sensor patch and sends alerts when values fall below 70 mg/dL. This is an example of:

Accepted Answer

Continuous remote patient monitoring (RPM)

Answer

Remote patient monitoring uses connected sensors to continuously collect and transmit physiological data, enabling real-time alerts outside clinical settings.

Question 5

In machine learning applied to medical imaging, 'data augmentation' is used to:

Accepted Answer

Artificially expand the training dataset using image transformations

Answer

Data augmentation applies transforms such as rotation, flipping, and cropping to existing images to increase training set diversity and reduce overfitting.

BMAT - Assessment Practice Test

BMAT - Assessment Practice Test

BMAT Technology & Digital Applications 4