BCPS BCPS Cardiovascular & Specialty Pharmacotherapy 3

Question 1

Which drug used for osteoporosis works by inhibiting RANK ligand, thereby reducing osteoclast activity?

Accepted Answer

Denosumab (RANK-L inhibitor)

Answer

Denosumab is a monoclonal antibody that inhibits RANK ligand, preventing osteoclast differentiation and reducing bone resorption.

Question 2

A patient with gout has a uric acid level of 9.8 mg/dL despite dietary changes. Which urate-lowering agent is first-line for chronic gout prevention?

Accepted Answer

Allopurinol

Answer

Allopurinol, a xanthine oxidase inhibitor, is the first-line urate-lowering therapy for chronic gout with a target serum uric acid <6 mg/dL.

Question 3

Which inhaled medication is the preferred first-line controller therapy for mild persistent asthma in adults?

Accepted Answer

Inhaled corticosteroid (ICS) such as fluticasone

Answer

Inhaled corticosteroids are the cornerstone of asthma controller therapy and are first-line for all persistent asthma due to their anti-inflammatory efficacy.

Question 4

A patient with COPD and frequent exacerbations (≥2/year) despite LAMA monotherapy should have which agent added to their regimen?

Accepted Answer

LABA + ICS combination

Answer

For COPD patients with frequent exacerbations on LAMA monotherapy, adding LABA + ICS (triple therapy) reduces exacerbation frequency per GOLD guidelines.

Question 5

Which pain management approach is recommended first-line for mild-to-moderate osteoarthritis pain before considering opioids or COX-2 inhibitors?

Accepted Answer

Acetaminophen or topical NSAIDs

Answer

Acetaminophen and topical NSAIDs are recommended first-line for mild-to-moderate osteoarthritis pain due to their favorable safety profiles.

(BCPS) Board Certified Pharmacotherapy Specialist Practice Test

(BCPS) Board Certified Pharmacotherapy Specialist Practice Test

BCPS BCPS Cardiovascular & Specialty Pharmacotherapy 3