ASPS ASPS Wound Healing & Tissue Management 1

Question 1

Which phase of wound healing is characterized by the formation of granulation tissue and angiogenesis?

Accepted Answer

Proliferative

Answer

The proliferative phase involves fibroblast activity, collagen deposition, and new blood vessel formation (angiogenesis) to build granulation tissue.

Question 2

What is the primary cell type responsible for wound contraction during healing?

Accepted Answer

Myofibroblast

Answer

Myofibroblasts, differentiated from fibroblasts, contain actin filaments that contract to reduce wound size.

Question 3

Which collagen type predominates in mature scar tissue remodeling?

Accepted Answer

Type I

Answer

Type I collagen, which is stronger and more organized, gradually replaces the Type III collagen deposited during early wound healing.

Question 4

A patient develops a raised, itchy scar that stays within wound borders 6 months post-op. This is best classified as:

Accepted Answer

Hypertrophic scar

Answer

Hypertrophic scars are elevated but remain within wound boundaries, unlike keloids which extend beyond the original wound margins.

Question 5

Which growth factor is most critical in initiating the wound healing cascade immediately after injury?

Accepted Answer

PDGF

Answer

Platelet-derived growth factor (PDGF), released from platelets during hemostasis, is among the first signals that recruit inflammatory cells and initiate healing.

(ASPS) American Society of Plastic Surgeons Practice Test

(ASPS) American Society of Plastic Surgeons Practice Test

ASPS ASPS Wound Healing & Tissue Management 1